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Time is a fundamental factor during stroke treatments. A fast, automatic approach that segments the ischemic regions helps treatment decisions. In clinical use today, a set of color-coded parametric maps generated from computed tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Luca Tomasetti , Mahdieh Khanmohammadi , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz

A key challenge in ischemic stroke diagnosis using medical imaging is the accurate localization of the occluded vessel. Current machine learning methods in focus primarily on lesion segmentation, with limited work on vessel localization. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Mohamed Hamad , Muhammad Khan , Tamer Khattab , Mohamed Mabrok

Stroke is known as a major global health problem, and for stroke survivors it is key to monitor the recovery levels. However, traditional stroke rehabilitation assessment methods (such as the popular clinical assessment) can be subjective…

Signal Processing · Electrical Eng. & Systems 2022-12-27 Xi Chen , Yu Guan , Jian Qing Shi , Xiu-Li Du , Janet Eyre

Intracranial hemorrhage occurs when blood vessels rupture or leak within the brain tissue or elsewhere inside the skull. It can be caused by physical trauma or by various medical conditions and in many cases leads to death. The treatment…

Computer Vision and Pattern Recognition · Computer Science 2021-05-14 Kimmo Kärkkäinen , Shayan Fazeli , Majid Sarrafzadeh

Accurate and generalisable segmentation of stroke lesions from magnetic resonance imaging (MRI) is essential for advancing clinical research, prognostic modelling, and personalised interventions. Although deep learning has improved…

Quantitative Methods · Quantitative Biology 2026-02-11 Tammar Truzman , Matthew A. Lambon Ralph , Ajay D. Halai

Recovery after stroke is often incomplete, but rehabilitation training may potentiate recovery by engaging endogenous neuroplasticity. In preclinical models of stroke, high doses of rehabilitation training are required to restore functional…

Signal Processing · Electrical Eng. & Systems 2020-06-22 Aakash Kaku , Avinash Parnandi , Anita Venkatesan , Natasha Pandit , Heidi Schambra , Carlos Fernandez-Granda

A stroke is defined as a neurologic deficit arising from an interruption in blood supply to the brain. According to the World Health Organization, over 15 million people suffer from strokes annually, of which almost 70% die or are…

Quantitative Methods · Quantitative Biology 2022-03-29 Rohan Kalahasty , Lakshmi Sritan Motati

Background: The brain's functional network constantly adapts to external changes. However, the mechanisms underlying this dynamic adaptive behavior in stroke patients with motor injuries and its role in post-stroke motor recovery remain…

Neurons and Cognition · Quantitative Biology 2024-01-18 Kaichao Wu , Beth Jelfs , Katrina Neville , Qiang Fang

The volume of stroke lesion is the gold standard for predicting the clinical outcome of stroke patients. However, the presence of stroke lesion may cause neural disruptions to other brain regions, and these potentially damaged regions may…

Image and Video Processing · Electrical Eng. & Systems 2020-07-01 Po-Yu Kao , Jefferson W. Chen , B. S. Manjunath

Introduction: Approximately 23 million or 30% of epilepsy patients worldwide suffer from drug-resistant epilepsy (DRE). The unpredictability of seizure occurrences, which causes safety issues as well as social concerns, restrict the…

Machine Learning · Computer Science 2024-10-10 Shriya Jaddu , Sidh Jaddu , Camilo Gutierrez , Quincy K. Tran

Stroke is among the top three causes of death worldwide, and accurate identification of ischemic stroke lesion boundaries from imaging is critical for diagnosis and treatment. The main imaging modalities used include magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Juampablo E. Heras Rivera , Hitender Oswal , Tianyi Ren , Yutong Pan , William Henry , Caitlin M. Neher , Mehmet Kurt

More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Luca Tomasetti , Kjersti Engan , Mahdieh Khanmohammadi , Kathinka Dæhli Kurz

Ischemic Stroke Lesion Segmentation challenge (ISLES 2022) offers a platform for researchers to compare their solutions to 3D segmentation of ischemic stroke regions from 3D MRIs. In this work, we describe our solution to ISLES 2022…

Image and Video Processing · Electrical Eng. & Systems 2022-09-22 Md Mahfuzur Rahman Siddique , Dong Yang , Yufan He , Daguang Xu , Andriy Myronenko

In the realm of medical imaging, precise segmentation of stroke lesions from brain MRI images stands as a critical challenge with significant implications for patient diagnosis and treatment. Addressing this, our study introduces an…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Mario Pascual González

As one of the leading causes of mortality and disability worldwide, Acute Ischemic Stroke (AIS) occurs when the blood supply to the brain is suddenly interrupted because of a blocked artery. Within seconds of AIS onset, the brain cells…

Image and Video Processing · Electrical Eng. & Systems 2022-11-17 Mohsen Soltanpour , Muhammad Yousefnezhad , Russ Greiner , Pierre Boulanger , Brian Buck

The preservation of the corticospinal tract (CST) is key to good motor recovery after stroke. The gold standard method of assessing the CST with imaging is diffusion tensor tractography. However, this is not available for most intracerebral…

Background and Purpose: We aimed to develop and evaluate an automatic acute ischemic stroke-related (AIS) detection system involving a two-stage deep learning model. Methods: We included 238 cases from two different institutions.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Mizuho Nishio , Sho Koyasu , Shunjiro Noguchi , Takao Kiguchi , Kanako Nakatsu , Thai Akasaka , Hiroki Yamada , Kyo Itoh

Ischemic stroke lesion segmentation from Computed Tomography Perfusion (CTP) images is important for accurate diagnosis of stroke in acute care units. However, it is challenged by low image contrast and resolution of the perfusion parameter…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Guotai Wang , Tao Song , Qiang Dong , Mei Cui , Ning Huang , Shaoting Zhang

Stroke is the second leading cause of disability worldwide. In order to minimize disability, the goal of stroke treatment is to preserve tissue in the area where blood supply is decreased but sufficient to stave off cell death. Thrombectomy…

Lesions that appear hyperintense in both Fluid Attenuated Inversion Recovery (FLAIR) and T2-weighted magnetic resonance images (MRIs) of the human brain are common in the brains of the elderly population and may be caused by ischemia or…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Hans E. Atlason , Askell Love , Sigurdur Sigurdsson , Vilmundur Gudnason , Lotta M. Ellingsen