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Carotid artery vessel wall thickness measurement is an essential step in the monitoring of patients with atherosclerosis. This requires accurate segmentation of the vessel wall, i.e., the region between an artery's lumen and outer wall, in…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Dieuwertje Alblas , Christoph Brune , Jelmer M. Wolterink

Diabetic retinopathy (DR) is a leading cause of vision loss worldwide, and early diagnosis through automated retinal image analysis can significantly reduce the risk of blindness. This paper presents a robust deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Faisal Ahmed

The utilisation of deep learning segmentation algorithms that learn complex organs and tissue patterns and extract essential regions of interest from the noisy background to improve the visual ability for medical image diagnosis has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-03 Yanming Guo

The precise detection of blood vessels in retinal images is crucial to the early diagnosis of the retinal vascular diseases, e.g., diabetic, hypertensive and solar retinopathies. Existing works often fail in predicting the abnormal areas,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Jun Wang , Yang Zhao , Linglong Qian , Xiaohan Yu , Yongsheng Gao

Diabetic Retinopathy (DR) is a constantly deteriorating disease, being one of the leading causes of vision impairment and blindness. Subtle distinction among different grades and existence of many significant small features make the task of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Sheikh Muhammad Saiful Islam , Md Mahedi Hasan , Sohaib Abdullah

Purpose: To investigate the impact of optic nerve tortuosity (ONT), and the interaction of globe proptosis and globe size on retinal ganglion cell (RGC) thickness, using Retinal Nerve Fiber Layer (RNFL) thickness, across general, glaucoma,…

Segmentation of macro and microvascular structures in fundoscopic retinal images plays a crucial role in the detection of multiple retinal and systemic diseases, yet it is a difficult problem to solve. Most neural network approaches face…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Shikhar Mohan , Saumik Bhattacharya , Sayantari Ghosh

Diabetic retinopathy is a severe eye condition caused by diabetes where the retinal blood vessels get damaged and can lead to vision loss and blindness if not treated. Early and accurate detection is key to intervention and stopping the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Shamim Rahim Refat , Ziyan Shirin Raha , Shuvashis Sarker , Faika Fairuj Preotee , MD. Musfikur Rahman , Tashreef Muhammad , Mohammad Shafiul Alam

Structural changes in retinal blood vessels are critical biomarkers for the onset and progression of glaucoma and other ocular diseases. However, current vessel segmentation approaches largely rely on supervised learning and extensive…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Cheng Huang , Weizheng Xie , Fan Gao , Yutong Liu , Ruoling Wu , Zeyu Han , Jingxi Qiu , Xiangxiang Wang , Zhenglin Yang , Hao Wang , Yongbin Yu

We present CaravelMetrics, a computational framework for automated cerebrovascular analysis that models vessel morphology through skeletonization-derived graph representations. The framework integrates atlas-based regional parcellation,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Daniele Falcetta , Liane S. Canas , Lorenzo Suppa , Matteo Pentassuglia , Jon Cleary , Marc Modat , Sébastien Ourselin , Maria A. Zuluaga

Diabetic Retinopathy (DR) is a leading cause of vision loss globally. Yet despite its prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for assessing their condition. This can…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Alexandros Papadopoulos , Fotis Topouzis , Anastasios Delopoulos

Blindness in diabetic patients caused by retinopathy (characterized by an increase in the diameter and new branches of the blood vessels inside the retina) is a grave concern. Many efforts have been made for the early detection of the…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Debojyoti Mallick , Kundan Kumar , Sumanshu Agarwal

Automatic segmentation of retina vessels plays a pivotal role in clinical diagnosis of prevalent eye diseases, such as, Diabetic Retinopathy or Age-related Macular Degeneration. Due to the complex construction of blood vessels, with…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Benjamin Hou

Diabetic retinopathy (DR) is a severe complication of diabetes that can cause permanent blindness. Timely diagnosis and treatment of DR are critical to avoid total loss of vision. Manual diagnosis is time consuming and error-prone. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 Ramya Bygari , Rachita Naik , Uday Kumar P

Cardiovascular disease (CVD) is the leading cause of mortality yet largely preventable, but the key to prevention is to identify at-risk individuals before adverse events. For predicting individual CVD risk, carotid intima-media thickness…

Computer Vision and Pattern Recognition · Computer Science 2017-06-05 Jae Y. Shin , Nima Tajbakhsh , R. Todd Hurst , Christopher B. Kendall , Jianming Liang

One of the fundamental challenges in drawing causal inferences from observational studies is that the assumption of no unmeasured confounding is not testable from observed data. Therefore, assessing sensitivity to this assumption's…

Methodology · Statistics 2024-06-25 Md Abdul Basit , Mahbub A. H. M. Latif , Abdus S Wahed

As a non-invasive imaging modality, optical coherence tomography (OCT) can provide micrometer-resolution 3D images of retinal structures. Therefore it is commonly used in the diagnosis of retinal diseases associated with edema in and under…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Morgan Heisler , Sieun Lee , Gavin Ding , Marinko V. Sarunic , Mirza Faisal Beg

We present a fully automatic, graph-based technique for extracting the retinal vascular topology -- that is, how different vessels are connected to each other -- given a single color fundus image. Determining this connectivity is very…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Aashis Khanal , Saeid Motevali , Rolando Estrada

Retinal vessel segmentation is crucial for intelligent ophthalmic diagnosis, yet it faces three major challenges: insufficient multi-scale feature fusion, disruption of contextual continuity, and noise interference. This study proposes a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Xinran Xu , Yuliang Ma , Sifu Cai , Ming Meng , Qiang Lv , Ruoyan Shi

Automatic extraction of retinal vascular biomarkers from color fundus images (CFI) is crucial for large-scale studies of the retinal vasculature. We present VascX, an open-source Python toolbox that extracts biomarkers from CFI artery-vein…