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Choroidal neovascularization (CNV), a primary characteristic of wet age-related macular degeneration (wet AMD), represents a leading cause of blindness worldwide. In clinical practice, optical coherence tomography angiography (OCTA) is…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Tao Chen , Dan Zhang , Da Chen , Huazhu Fu , Kai Jin , Shanshan Wang , Laurent D. Cohen , Yitian Zhao , Quanyong Yi , Jiong Zhang

In the medical image analysis field, precise quantification of curve tortuosity plays a critical role in the auxiliary diagnosis and pathological assessment of various diseases. In this study, we propose a novel framework for tortuosity…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Kesheng Wang , Xiaoyu Chen , Chunlei He , Fenfen Li , Xinxin Yu , Dexing Kong , Shoujun Huang , Qi Dai

Tuberculosis (TB) remains a global health problem, and is the leading cause of death from an infectious disease. A crucial step in the treatment of tuberculosis is screening high risk populations and the early detection of the disease, with…

Image and Video Processing · Electrical Eng. & Systems 2021-04-15 Alexander Wong , James Ren Hou Lee , Hadi Rahmat-Khah , Ali Sabri , Amer Alaref

Retinal vessel information is helpful in retinal disease screening and diagnosis. Retinal vessel segmentation provides useful information about vessels and can be used by physicians during intraocular surgery and retinal diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2018-02-23 M. Hajabdollahi , R. Esfandiarpoor , S. M. R. Soroushmehr , N. Karimi , S. Samavi , K. Najarian

Vessel segmentation is crucial in many medical image applications, such as detecting coronary stenoses, retinal vessel diseases and brain aneurysms. However, achieving high pixel-wise accuracy, complete topology structure and robustness to…

Computer Vision and Pattern Recognition · Computer Science 2023-05-11 Tianyi Shi , Xiaohuan Ding , Wei Zhou , Feng Pan , Zengqiang Yan , Xiang Bai , Xin Yang

Elderly ICU patients with coexisting diabetes mellitus and heart failure experience markedly elevated short-term mortality, yet few predictive models are tailored to this high-risk group. Diabetes mellitus affects nearly 30% of U.S. adults…

Applications · Statistics 2025-06-19 Junyi Fan , Shuheng Chen , Li Sun , Yong Si , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Optical coherence tomography (OCT) is used for non-invasive diagnosis of diabetic macular edema assessing the retinal layers. In this paper, we propose a new fully convolutional deep architecture, termed ReLayNet, for end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Abhijit Guha Roy , Sailesh Conjeti , Sri Phani Krishna Karri , Debdoot Sheet , Amin Katouzian , Christian Wachinger , Nassir Navab

Early detection of cardiovascular disease risk factors is essential to alter the course of the disease. Previous studies showed that deep learning can successfully be used to detect such risk factors from retinal images. This study uses…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Andrea Prenner

The comorbidities of hypertension impose a heavy burden on patients and society. Early identification is necessary to prompt intervention, but it remains a challenging task. This study aims to address this challenge by combining joint graph…

Machine Learning · Computer Science 2025-06-13 Leming Zhou , Zuo Wang , Zhixuan Duan

Patient-specific computational modeling is a popular, non-invasive method to answer medical questions. Medical images are used to extract geometric domains necessary to create these models, providing a predictive tool for clinicians.…

Accurate estimation of shape thickness from medical images is crucial in clinical applications. For example, the thickness of myocardium is one of the key to cardiac disease diagnosis. While mathematical models are available to obtain…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Qiaoying Huang , Eric Z. Chen , Hanchao Yu , Yimo Guo , Terrence Chen , Dimitris Metaxas , Shanhui Sun

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

Retinal vessel segmentation is a crucial step in diagnosing and screening various diseases, including diabetes, ophthalmologic diseases, and cardiovascular diseases. In this paper, we propose an effective and efficient method for vessel…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Zhun Fan , Jiajie Mo , Benzhang Qiu , Wenji Li , Guijie Zhu , Chong Li , Jianye Hu , Yibiao Rong , Xinjian Chen

Vasculature is known to be of key biological significance, especially in the study of cancer. As such, considerable effort has been focused on the automated measurement and analysis of vasculature in medical and pre-clinical images. In…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Russell Bates , Benjamin Irving , Bostjan Markelc , Jakob Kaeppler , Ruth Muschel , Vicente Grau , Julia A. Schnabel

Retinal lesions play a vital role in the accurate classification of retinal abnormalities. Many researchers have proposed deep lesion-aware screening systems that analyze and grade the progression of retinopathy. However, to the best of our…

Computer Vision and Pattern Recognition · Computer Science 2020-08-17 Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

Extracting blood vessels from retinal fundus images plays a decisive role in diagnosing the progression in pertinent diseases. In medical image analysis, vessel extraction is a semantic binary segmentation problem, where blood vasculature…

Image and Video Processing · Electrical Eng. & Systems 2022-03-21 Kundan Kumar , Sumanshu Agarwal

The prevalence of diabetic retinopathy (DR) has reached 34.6% worldwide and is a major cause of blindness among middle-aged diabetic patients. Regular DR screening using fundus photography helps detect its complications and prevent its…

Image and Video Processing · Electrical Eng. & Systems 2022-11-09 Fahman Saeed , Muhammad Hussain , Hatim A Aboalsamh , Fadwa Al Adel , Adi Mohammed Al Owaifeer

Shape graphs are complex geometrical structures commonly found in biological and anatomical systems. A shape graph is a collection of nodes, some connected by curvilinear edges with arbitrary shapes. Their high complexity stems from the…

Computation · Statistics 2024-09-17 Benjamin Beaudett , Anuj Srivastava

Retinal fundus images can be an invaluable diagnosis tool for screening epidemic diseases like hypertension or diabetes. And they become especially useful when the arterioles and venules they depict are clearly identified and annotated.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Angel Victor Juanco Muller , Joao F. C. Mota , Keith A. Goatman , Corne Hoogendoorn

Purpose: To assess whether the three-dimensional (3D) structural configuration of the central retinal vessel trunk and its branches (CRVT&B) could be used as a diagnostic marker for glaucoma. Method: We trained a deep learning network to…