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We present AURA-net, a convolutional neural network (CNN) for the segmentation of phase-contrast microscopy images. AURA-net uses transfer learning to accelerate training and Attention mechanisms to help the network focus on relevant image…

Image and Video Processing · Electrical Eng. & Systems 2021-02-03 Ethan Cohen , Virginie Uhlmann

The advancements in deep learning technologies have produced immense contributions to biomedical image analysis applications. With breast cancer being the common deadliest disease among women, early detection is the key means to improve…

Image and Video Processing · Electrical Eng. & Systems 2022-02-04 Narinder Singh Punn , Sonali Agarwal

Synthetic PET images are valuable for quantitative imaging workflow development, scalable virtual imaging trials, and deep learning model training, but conventional physics-based simulation approaches are computationally intensive, limited…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Suya Li , Kaushik Dutta , Debojyoti Pal , Jingqin Luo , Kooresh I. Shoghi

Magnetic resonance imaging (MRI) and positron emission tomography (PET) are increasingly used in multimodal analysis of neurodegenerative disorders. While MRI is broadly utilized in clinical settings, PET is less accessible. Many studies…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Minhui Yu , Mengqi Wu , Ling Yue , Andrea Bozoki , Mingxia Liu

We propose a novel attention gate (AG) model for medical imaging that automatically learns to focus on target structures of varying shapes and sizes. Models trained with AGs implicitly learn to suppress irrelevant regions in an input image…

MRI and PET are important modalities and can provide complementary information for the diagnosis of brain diseases because MRI can provide structural information of brain and PET can obtain functional information of brain. However, PET is…

Multimedia · Computer Science 2023-04-18 Taofeng Xie , Chentao Cao , Zhuoxu Cui , Fanshi Li , Zidong Wei , Yanjie Zhu , Ye Li , Dong Liang , Qiyu Jin , Guoqing Chen , Haifeng Wang

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Diagnosing dementia, particularly for Alzheimer's Disease (AD) and frontotemporal dementia (FTD), is complex due to overlapping symptoms. While magnetic resonance imaging (MRI) and positron emission tomography (PET) data are critical for…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Yitong Li , Morteza Ghahremani , Youssef Wally , Christian Wachinger

Image representations are commonly learned from class labels, which are a simplistic approximation of human image understanding. In this paper we demonstrate that transferable representations of images can be learned without manual…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Richard Droste , Yifan Cai , Harshita Sharma , Pierre Chatelain , Lior Drukker , Aris T. Papageorghiou , J. Alison Noble

Recently, Visual Transformer (ViT) has been widely used in various fields of computer vision due to applying self-attention mechanism in the spatial domain to modeling global knowledge. Especially in medical image segmentation (MIS), many…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Jiacheng Ruan , Mingye Xie , Suncheng Xiang , Ting Liu , Yuzhuo Fu

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that predominantly affects the elderly population and currently has no cure. Magnetic Resonance Imaging (MRI), as a non-invasive imaging technique, is essential for the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Xinyue Yang , Meiliang Liu , Yunfang Xu , Xiaoxiao Yang , Zhengye Si , Zijin Li , Zhiwen Zhao

Although supervised convolutional neural networks (CNNs) often outperform conventional alternatives for denoising positron emission tomography (PET) images, they require many low- and high-quality reference PET image pairs. Herein, we…

Medical Physics · Physics 2021-09-29 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Hiroyuki Ohba , Ryosuke Ota , Etsuji Yoshikawa , Yasuomi Ouchi

Magnetic resonance imaging (MRI) is highly sensitive for lesion detection in the breasts. Sequences obtained with different settings can capture the specific characteristics of lesions. Such multi-parameter MRI information has been shown to…

Image and Video Processing · Electrical Eng. & Systems 2023-02-06 Tianyu Zhang , Tao Tan , Luyi Han , Xin Wang , Yuan Gao , Jonas Teuwen , Regina Beets-Tan , Ritse Mann

Tumor segmentation in PET-CT images is challenging due to the dual nature of the acquired information: low metabolic information in CT and low spatial resolution in PET. U-Net architecture is the most common and widely recognized approach…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Simone Bendazzoli , Mehdi Astaraki

Positron emission tomography (PET) offers powerful functional imaging but involves radiation exposure. Efforts to reduce this exposure by lowering the radiotracer dose or scan time can degrade image quality. While using magnetic resonance…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Yingkai Zhang , Shuang Chen , Ye Tian , Yunyi Gao , Jianyong Jiang , Ying Fu

Medical imaging datasets are inherently high dimensional with large variability and low sample sizes that limit the effectiveness of deep learning algorithms. Recently, generative adversarial networks (GANs) with the ability to synthesize…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Apoorva Sikka , Skand Peri , Jitender Singh Virk , Usma Niyaz , Deepti R. Bathula

In this work, an image translation model is implemented to produce synthetic amyloid-beta PET images from structural MRI that are quantitatively accurate. Image pairs of amyloid-beta PET and structural MRI were used to train the model. We…

Image and Video Processing · Electrical Eng. & Systems 2023-09-04 Fernando Vega , Abdoljalil Addeh , M. Ethan MacDonald

Synthesizing medical images, such as PET, is a challenging task due to the fact that the intensity range is much wider and denser than those in photographs and digital renderings and are often heavily biased toward zero. Above all,…

Positron Emission Tomography (PET) imaging is a vital tool in medical diagnostics, offering detailed insights into molecular processes within the human body. However, PET images often suffer from complicated noise, which can obscure…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Xuehua Ye , Hongxu Yang , Adam J. Schwarz