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Unbalanced optimal transport (UOT) provides a principled framework for modeling single-cell transitions and birth-death dynamics, but its high computational cost limits scalability to large-scale datasets. Although single-cell data often…

Machine Learning · Computer Science 2026-05-19 Qiangwei Peng , Lezhi Chen , Peijie Zhou

The accurate and stable simulation of viscoelastic flows remains a significant computational challenge, exacerbated for flows in non-trivial and practical geometries. Here we present a new high-order meshless approach with variable…

Fluid Dynamics · Physics 2024-05-01 Jack R. C. King , Steven J. Lind

Estimating density ratios between pairs of intractable data distributions is a core problem in probabilistic modeling, enabling principled comparisons of sample likelihoods under different data-generating processes across conditions and…

Machine Learning · Computer Science 2026-03-02 Egor Antipov , Alessandro Palma , Lorenzo Consoli , Stephan Günnemann , Andrea Dittadi , Fabian J. Theis

We study analytically the dynamics and the micro-structural changes of a host medium caused by a driven tracer particle moving in a confined, quiescent molecular crowding environment. Imitating typical settings of active micro-rheology…

Statistical Mechanics · Physics 2016-03-17 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

Optical flow is a fundamental technique for motion estimation, widely applied in video stabilization, interpolation, and object tracking. Traditional optical flow estimation methods rely on restrictive assumptions like brightness constancy…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Yu-Hsi Chen , Chin-Tien Wu

Machine Learning (ML) models in Robotic Assembly Sequence Planning (RASP) need to be introspective on the predicted solutions, i.e. whether they are feasible or not, to circumvent potential efficiency degradation. Previous works need both…

We develop a stochastic model for the programmed frameshift of ribosomes synthesizing a protein while moving along a mRNA template. Normally the reading frame of a ribosome decodes successive triplets of nucleotides on the mRNA in a…

Biological Physics · Physics 2017-06-01 Bhavya Mishra , Gunter M. Schütz , Debashish Chowdhury

Amorphous elastomers exhibit significant rate-stiffening and unique viscous flow characteristics across a wide range of strain rates, often undergoing glass transition above a strain rate threshold. We have developed a…

Soft Condensed Matter · Physics 2026-05-26 Bibekananda Datta , Sushan Nakarmi , Nitin P. Daphalapurkar

The totally asymmetric simple exclusion process (TASEP) is a paradigmatic lattice model for one-dimensional particle transport subject to excluded-volume interactions. Solving the inhomogeneous TASEP in which particles' hopping rates vary…

Statistical Mechanics · Physics 2023-10-31 Luca Ciandrini , Richmond L. Crisostomo , Juraj Szavits-Nossan

The totally asymmetric exclusion process (TASEP) with periodic boundaries is considered as traffic flow model. The large-L approximation of the stationary state is used for the derivation of the time-headway distribution (an important…

Statistical Mechanics · Physics 2018-01-08 Pavel Hrabák , Milan Krbálek

Flow matching has recently emerged as a powerful framework for continuous-time generative modeling. However, when applied to long-tailed distributions, standard flow matching suffers from majority bias, producing minority modes with low…

Machine Learning · Computer Science 2025-10-01 Hyunsoo Song , Minjung Gim , Jaewoong Choi

We propose Delta Rectified Flow Sampling (DRFS), a novel inversion-free, path-aware editing framework within rectified flow models for text-to-image editing. DRFS is a distillation-based method that explicitly models the discrepancy between…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Gaspard Beaudouin , Minghan Li , Jaeyeon Kim , Sung-Hoon Yoon , Mengyu Wang

Under certain cellular conditions, transcription and mRNA translation in prokaryotes appear to be "coupled," in which the formation of mRNA transcript and production of its associated protein are temporally correlated. Such…

Subcellular Processes · Quantitative Biology 2026-05-12 Xiangting Li , Tom Chou

Transcription is a complex phenomenon that permits the conversion of genetic information into phenotype by means of an enzyme called RNA polymerase, which erratically moves along and scans the DNA template. We perform Bayesian inference…

Biological Physics · Physics 2023-07-18 Massimo Cavallaro , Yuexuan Wang , Daniel Hebenstreit , Ritabrata Dutta

Interactions between an internal flow and wall deformation occur in many biological systems. Such interactions can involve a complex and rich dynamical behavior and a number of peculiarities which depend on the flow parameter range. The aim…

Fluid Dynamics · Physics 2019-03-11 Mustapha Amaouche , Giuseppe Di Labbio

Tensor decomposition is an important technique for capturing the high-order interactions among multiway data. Multi-linear tensor composition methods, such as the Tucker decomposition and the CANDECOMP/PARAFAC (CP), assume that the complex…

Machine Learning · Statistics 2016-11-04 Bin Liu , Zenglin Xu , Yingming Li

We introduce a multi-species lattice gas model for motor protein driven collective cargo transport on cellular filaments. We use this model to describe and analyze the collective motion of interacting vesicle cargoes being carried by…

Statistical Mechanics · Physics 2010-09-10 Sudipto Muhuri , Ignacio Pagonabarraga

Diversified distribution matching (DDM) finds a unified translation function mapping a diverse collection of conditional source distributions to their target counterparts. DDM was proposed to resolve content misalignment issues in unpaired…

Machine Learning · Computer Science 2025-11-11 Sagar Shrestha , Xiao Fu

Encoder-decoder models have achieved remarkable success in speech and text tasks, yet efficiently adapting these models to diverse uni/multi-modal scenarios remains an open challenge. In this paper, we propose Whisper-UT, a unified and…

Boltzmann generators approach the sampling problem in many-body physics by combining a normalizing flow and a statistical reweighting method to generate samples of a physical system's equilibrium density. The equilibrium distribution is…

Computational Physics · Physics 2020-12-02 Manuel Dibak , Leon Klein , Frank Noé
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