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With the rapid development of computer software and hardware technologies, more and more healthcare data are becoming readily available from clinical institutions, patients, insurance companies and pharmaceutical industries, among others.…

Machine Learning · Computer Science 2020-08-24 Jie Xu , Benjamin S. Glicksberg , Chang Su , Peter Walker , Jiang Bian , Fei Wang

The sharing of patient-level data necessary for covariate-adjusted survival analysis between medical institutions is difficult due to privacy protection restrictions. We propose a privacy-preserving framework that estimates balanced…

Deep Learning has established in the latest years as a successful approach to address a great variety of tasks. Healthcare is one of the most promising field of application for Deep Learning approaches since it would allow to help…

Machine Learning · Computer Science 2021-10-05 Edoardo Giacomello , Michele Cataldo , Daniele Loiacono , Pier Luca Lanzi

The increasing need for sharing healthcare data and collaborating on clinical research has raised privacy concerns. Health information leakage due to malicious attacks can lead to serious problems such as misdiagnoses and patient…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Shiyi Jiang , Farshad Firouzi , Krishnendu Chakrabarty

Background: In the context of ongoing debate over data confidentiality versus shared use of research data, as raised following the new EU General Data Protection Regulation, we seek to find alternate techniques that can balance these two…

Applications · Statistics 2016-06-20 Paramita Saha-Chaudhuri , Clarice Weinberg

In this paper, we propose a data collaboration analysis method for distributed datasets. The proposed method is a centralized machine learning while training datasets and models remain distributed over some institutions. Recently, data…

Machine Learning · Computer Science 2019-02-21 Akira Imakura , Tetsuya Sakurai

This paper proposes a data privacy protection framework based on federated learning, which aims to realize effective cross-domain data collaboration under the premise of ensuring data privacy through distributed learning. Federated learning…

Machine Learning · Computer Science 2025-04-02 Yiwei Zhang , Jie Liu , Jiawei Wang , Lu Dai , Fan Guo , Guohui Cai

With increasing concerns over privacy in healthcare, especially for sensitive medical data, this research introduces a federated learning framework that combines local differential privacy and secure aggregation using Secure Multi-Party…

Machine Learning · Computer Science 2024-12-03 Mohamad Haj Fares , Ahmed Mohamed Saad Emam Saad

A large amount of data and applications need to be shared with various parties and stakeholders in the cloud environment for storage, computation, and data utilization. Since a third party operates the cloud platform, owners cannot fully…

Cryptography and Security · Computer Science 2022-12-26 Ashutosh Kumar Singh , Rishabh Gupta

Federated learning (FL) has been proposed to allow collaborative training of machine learning (ML) models among multiple parties where each party can keep its data private. In this paradigm, only model updates, such as model weights or…

Machine Learning · Computer Science 2021-06-18 Runhua Xu , Nathalie Baracaldo , Yi Zhou , Ali Anwar , James Joshi , Heiko Ludwig

Objective: The proper handling of missing values is critical to delivering reliable estimates and decisions, especially in high-stakes fields such as clinical research. The increasing diversity and complexity of data have led many…

Privacy protection and uncertainty quantification are increasingly important in data-driven decision making. Conformal prediction provides finite-sample marginal coverage, but existing private approaches often rely on data splitting,…

Machine Learning · Statistics 2026-03-10 Young Hyun Cho , Jordan Awan

Huge volume of data from domain specific applications such as medical, financial, library, telephone, shopping records and individual are regularly generated. Sharing of these data is proved to be beneficial for data mining application. On…

Databases · Computer Science 2013-06-07 Hitesh Chhinkaniwala , Sanjay Garg

Private synthetic data sharing is preferred as it keeps the distribution and nuances of original data compared to summary statistics. The state-of-the-art methods adopt a select-measure-generate paradigm, but measuring large domain…

Cryptography and Security · Computer Science 2023-10-11 Meifan Zhang , Dihang Deng , Lihua Yin

Feature selection is the process of sieving features, in which informative features are separated from the redundant and irrelevant ones. This process plays an important role in machine learning, data mining and bioinformatics. However,…

Cryptography and Security · Computer Science 2020-08-19 Javad Rahimipour Anaraki , Saeed Samet

Integrative analysis of datasets generated by multiple cohorts is a widely-used approach for increasing sample size, precision of population estimators, and generalizability of analysis results in epidemiological studies. However, often…

Privacy preserving multi-party computation has many applications in areas such as medicine and online advertisements. In this work, we propose a framework for distributed, secure machine learning among untrusted individuals. The framework…

Cryptography and Security · Computer Science 2018-11-27 Yunhui Long , Tanmay Gangwani , Haris Mughees , Carl Gunter

This paper investigates the privacy-preserving distributed optimization problem, aiming to protect agents' private information from potential attackers during the optimization process. Gradient tracking, an advanced technique for improving…

Machine Learning · Computer Science 2025-09-24 Furan Xie , Bing Liu , Li Chai

In multicenter biomedical research, integrating data from multiple decentralized sites provides more robust and generalizable findings due to its larger sample size and the ability to account for the between-site heterogeneity. However,…

Methodology · Statistics 2025-12-29 Xiaokang Liu , Yuchen Yang , Yifei Sun , Jiang Bian , Yanyuan Ma , Raymond J. Carroll , Yong Chen

Digital agriculture leverages technology to enhance crop yield, disease resilience, and soil health, playing a critical role in agricultural research. However, it raises privacy concerns such as adverse pricing, price discrimination, higher…

Machine Learning · Computer Science 2024-09-12 Osama Zafar , Rosemarie Santa Gonzalez , Gabriel Wilkins , Alfonso Morales , Erman Ayday