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Guided by extensive numerical simulations, we propose a microfluidic device that can sort elastic capsules by their deformability. The device consists of a duct embedded with a semi-cylindrical obstacle, and a diffuser which further…

Fluid Dynamics · Physics 2014-09-18 Lailai Zhu , Cecilia Rorai , Dhrubaditya Mitra , Luca Brandt

Elastic capsules, prepared from droplets or bubbles attached to a capillary (as in a pendant drop tensiometer), can be deflated by suction through the capillary. We study this deflation and show that a combined analysis of the shape and…

Soft Condensed Matter · Physics 2013-10-21 Sebastian Knoche , Dominic Vella , Elodie Aumaitre , Patrick Degen , Heinz Rehage , Pietro Cicuta , Jan Kierfeld

Soft matters whose constituents are deformable are ubiquitous in nature especially in biological systems-including cells and their organelles-as well as in foams and emulsions. The capacity for deformation in these soft materials gives rise…

Soft Condensed Matter · Physics 2026-03-05 Padmanabha Bose , Smarajit Karmakar

The size- and fluorescence-based sorting of micro- and nano-scale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here we demonstrate…

Soft Condensed Matter · Physics 2015-02-16 Sukumar Rajauria , Christopher Axline , Claudia Gottstein , Andrew N. Cleland

We study experimentally the motion and deformation of individual capsules transported by a constant volume-flux flow of low Reynolds number, through the T-junction of a channel with rectangular cross-section. We use millimetric…

Soft Condensed Matter · Physics 2020-02-19 E. Häner , M. Heil , A. Juel

We present a deformation-dependent propulsion phenomenon for soft particles such as cells in microchannels. It is based on a broken time reversal symmetry generated by a fast forward and slow backward motion of a fluid which does not…

Soft Condensed Matter · Physics 2022-02-22 Winfried Schmidt , Andre Förtsch , Matthias Laumann , Walter Zimmermann

We study the rheology of a suspension of soft deformable droplets subjected to a pressure-driven flow. Through computer simulations, we measure the apparent viscosity as a function of droplet concentration and pressure gradient, and provide…

Soft Condensed Matter · Physics 2017-11-22 M. Foglino , A. N. Morozov , O. Henrich , D. Marenduzzo

In this fluid dynamics video, we compare the deformation of two flexible particles as they propagate through a sudden constriction of a liquid filled channel under constant-flux flow: a gas bubble, and a capsule formed by encapsulating a…

Fluid Dynamics · Physics 2013-10-11 Geoffrey Dawson , Anne Juel

We study numerically how multiple deformable capsules squeeze into a constriction. This situation is largely encountered in microfluidic chips designed to manipulate living cells, which are soft entities. We use fully three-dimensional…

Soft Condensed Matter · Physics 2021-12-15 Clément Bielinski , Othmane Aouane , Jens Harting , Badr Kaoui

Sorting and separation of microparticles is a challenging problem of interdisciplinary nature. Existing technologies can differentiate microparticles by their bulk properties, such as size, density, electric polarizability, etc. The next…

Soft Condensed Matter · Physics 2018-09-03 Chenhui Peng , Taras Turiv , Yubing Guo , Qi-Huo Wei , Oleg D. Lavrentovich

The shear-induced deformation of a capsule with a stiff nucleus, a model of eukaryotic cells, is studied numerically. The membrane of the cell and of its nucleus are modelled as a thin and impermeable elastic material obeying a Neo-Hookean…

Fluid Dynamics · Physics 2017-05-29 Arash Alizad Banaei , Jean-Christophe Loiseau , Iman Lashgari , Luca Brandt

A computational study of capsule ejection from a narrow channel into a reservoir is undertaken for a combination of varying deformable capsule sizes and channel dimensions. A mass spring membrane model is coupled to an Immersed Boundary…

Soft Condensed Matter · Physics 2019-07-02 Alessandro Coclite , Alberto Gambaruto

This paper deals with flow-induced shape transitions of elastic capsules. The state of the art concerning both theory and experiments is briefly reviewed starting with dynamically induced small deformation of initially spherical capsules…

Soft Condensed Matter · Physics 2011-04-25 Reimar Finken , Steffen Kessler , Udo Seifert

The deformation of an elastic micro-capsule in an infinite shear flow is studied numerically using a spectral method. The shape of the capsule and the hydrodynamic flow field are expanded into smooth basis functions. Analytic expressions…

Soft Condensed Matter · Physics 2008-09-03 S. Kessler , R. Finken , U. Seifert

Spatial segregation in the wall normal direction is investigated in suspensions containing a binary mixture of Neo-Hookean capsules subjected to pressure driven flow in a planar slit. The two components of the binary mixture have unequal…

Soft Condensed Matter · Physics 2011-12-30 Amit Kumar , Michael D. Graham

We investigate the inertial and non-inertial dynamics of three-dimensional elastic capsules flowing through a square channel presenting a sharp corner. Our study analyzes the trajectory, surface area, velocity and membrane stress of the…

Fluid Dynamics · Physics 2023-05-09 Damien P. Huet , Antoine Morente , Guodong Gai , Anthony Wachs

We study deformability-based sorting of same-size RBCs via DLD using an in-house integral equation solver. Our goal is to quantitatively characterize the physical mechanisms that enable the cell separation. To this end, we systematically…

Computational Physics · Physics 2018-11-30 Gokberk Kabacaoglu , George Biros

We present an experimental method to fabricate centimetric thin elastic capsules with highly uniform thickness and negligible bending stiffness using silicone elastomers. In our experiments, the capsules thickness is tunable at fabrication,…

Soft Condensed Matter · Physics 2026-03-05 Antonin Eddi , Stéphane Perrard , Jishen Zhang

A three-dimensional deformable capsule convected through a square duct with a corner is studied via numerical simulations. We develop an accelerated boundary integral implementation adapted to general geometries and boundary conditions. A…

Fluid Dynamics · Physics 2015-06-22 Lailai Zhu , Luca Brandt

Using dynamical density functional theory we calculate the speed of solidification fronts advancing into a quenched two-dimensional model fluid of soft-core particles. We find that solidification fronts can advance via two different…

Soft Condensed Matter · Physics 2014-10-22 A. J. Archer , M. C. Walters , U. Thiele , E. Knobloch
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