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Measurements are generally collected as unilateral or bilateral data in clinical trials or observational studies. For example, in ophthalmologic studies, statistical tests are often based on one or two eyes of an individual. For bilateral…

Methodology · Statistics 2020-10-08 Chang-Xing Ma , Kejia Wang

The classical theory for the meta-analysis of $p$-values is based on the assumption that if the overall null hypothesis is true, then all $p$-values used in a chosen combined test statistic are genuine, i.e., are observations from…

Computation · Statistics 2024-10-08 Rui Santos , M. Fátima Brilhante , Sandra Mendonça

Small study effects occur when smaller studies show different, often larger, treatment effects than large ones, which may threaten the validity of systematic reviews and meta-analyses. The most well-known reasons for small study effects…

The problem of detecting changes in covariance for a single pair of features has been studied in some detail, but may be limited in importance or general applicability. In contrast, testing equality of covariance matrices of a {\it set} of…

Methodology · Statistics 2017-12-12 Yi-Hui Zhou

Testing for a mediation effect is important in many disciplines, but is made difficult - even asymptotically - by the influence of nuisance parameters. Classical tests such as likelihood ratio (LR) and Wald (Sobel) tests have very poor…

Econometrics · Economics 2024-03-05 Grant Hillier , Kees Jan van Garderen , Noud van Giersbergen

Items in a test are often used as a basis for making decisions and such tests are therefore required to have good psychometric properties, like unidimensionality. In many cases the sum score is used in combination with a threshold to decide…

Methodology · Statistics 2020-07-14 Lourens Waldorp , Maarten Marsman , Denny Borsboom

We investigate the likelihood ratio test for a large block-diagonal covariance matrix with an increasing number of blocks under the null hypothesis. While so far the likelihood ratio statistic has only been studied for normal populations,…

Statistics Theory · Mathematics 2024-08-01 Nina Dörnemann

Scoring rules are aimed at evaluation of the quality of predictions, but can also be used for estimation of parameters in statistical models. We propose estimating parameters of multivariate spatial models by maximising the average…

Methodology · Statistics 2024-08-23 Helga Kristin Olafsdottir , Holger Rootzén , David Bolin

Limit distributions of likelihood ratio statistics are well-known to be discontinuous in the presence of nuisance parameters at the boundary of the parameter space, which lead to size distortions when standard critical values are used for…

Econometrics · Economics 2025-07-29 Giuseppe Cavaliere , Adam McCloskey , Rasmus S. Pedersen , Anders Rahbek

The problem of testing changes in covariance has received increasing attention in recent years, especially in the context of high-dimensional testing. A number of approaches have been proposed, all limited to the two-sample problem and…

Methodology · Statistics 2016-09-06 Yi-Hui Zhou

New tests are developed for two-way ANOVA models with heterogeneous error variances. The testing problems are considered for testing the significant interaction effects, simple effects, and treatment effects. The likelihood ratio tests…

Methodology · Statistics 2026-03-02 Anjana Mondal , Somesh Kumar

This paper introduces a likelihood ratio (LR)-type test that possesses the robustness properties of \(C(\alpha)\)-type procedures in an extremum estimation setting. The test statistic is constructed by applying separate adjustments to the…

Econometrics · Economics 2025-10-21 Jean-Marie Dufour , Purevdorj Tuvaandorj

We consider the problem of testing for a dose-related effect based on a candidate set of (typically nonlinear) dose-response models using likelihood-ratio tests. For the considered models this reduces to assessing whether the slope…

Methodology · Statistics 2015-10-22 Georg Gutjahr , Björn Bornkamp

For high-dimensional small sample size data, Hotelling's T2 test is not applicable for testing mean vectors due to the singularity problem in the sample covariance matrix. To overcome the problem, there are three main approaches in the…

Methodology · Statistics 2020-03-11 Zongliang Hu , Tiejun Tong , Marc G. Genton

Two parties observe independent copies of a $d$-dimensional vector and a scalar. They seek to test if their data is correlated or not, namely they seek to test if the norm $\|\rho\|_2$ of the correlation vector $\rho$ between their…

Information Theory · Computer Science 2020-05-22 K. R. Sahasranand , Himanshu Tyagi

The ROC curve is a statistical tool that analyses the accuracy of a diagnostic test in which a variable is used to decide whether an individual is healthy or not. Along with that diagnostic variable it is usual to have information of some…

The e-value is swiftly rising in prominence in many applications of hypothesis testing and multiple testing, yet its relationship to classical testing theory remains elusive. We unify e-values and classical testing into a single 'continuous…

Statistics Theory · Mathematics 2025-05-12 Nick W. Koning

In this work, we are motivated by the recent work of Zhang et al. (2019) and study a new invariant test for equality of two large scale covariance matrices. Two modified likelihood ratio tests (LRTs) by Zhang et al. (2019) are based on the…

Statistics Theory · Mathematics 2019-11-15 Taehyeon Koo , Seonghun Cho , Johan Lim

The standard paired-sample testing approach in the multidimensional setting applies multiple univariate tests on the individual features, followed by p-value adjustments. Such an approach suffers when the data carry numerous features. A…

Machine Learning · Statistics 2023-09-29 Ioannis Bargiotas , Argyris Kalogeratos , Nicolas Vayatis

We consider the hypothesis testing problem of deciding whether an observed high-dimensional vector has independent normal components or, alternatively, if it has a small subset of correlated components. The correlated components may have a…

Statistics Theory · Mathematics 2012-06-04 Ery Arias-Castro , Sébastien Bubeck , Gábor Lugosi