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Microwave-based breast cancer detection has been proposed as a complementary approach to compensate for some drawbacks of existing breast cancer detection techniques. Among the existing microwave breast cancer detection methods, machine…

Machine Learning · Statistics 2017-02-27 Hongchao Song , Yunpeng Li , Mark Coates , Aidong Men

Many lives can be saved if tumors are detected in early stages, which can result in a bigger chance for recovery. Many patients find it irritating to get regular checkups due to the fact that the majority of the monitoring systems are…

Signal Processing · Electrical Eng. & Systems 2018-09-21 Hamad AlShehhi , Mariam Alzarouni , Noura AlYammahi , Raed Shubair , Nazar Ali

Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…

Recent ultrasound imaging modalities based on ultrasound computed tomography indicate a huge potential to detect pathologies is tissue due to altered biomechanical properties. Especially the imaging of speed-of-sound (SoS) distribution in…

Medical Physics · Physics 2021-07-05 Richard Rau , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

Recent advances in high-resolution biomedical imaging focusing on morphological, electrical, and biochemical properties of cells and tissues, scaling from cell clusters down to the molecular level, have improved cancer diagnosis. Multiscale…

Medical Physics · Physics 2023-04-21 Phat K. Huynh , Dang Nguyen , Grace Binder , Sharad Ambardar , Trung Q. Le , Dmitri V. Voronine

Molecular phenotyping by gene expression profiling is common in contemporary cancer research and in molecular diagnostics. However, molecular profiling remains costly and resource intense to implement, and is just starting to be introduced…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Philippe Weitz , Yinxi Wang , Kimmo Kartasalo , Lars Egevad , Johan Lindberg , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Accurate segmentation of tumors and adjacent normal tissues in medical images is essential for surgical planning and tumor staging. Although foundation models generally perform well in segmentation tasks, they often struggle to focus on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Kai Han , Siqi Ma , Chengxuan Qian , Jun Chen , Chongwen Lyu , Yuqing Song , Zhe Liu

Accurate detection of brain tumors could save lots of lives and increasing the accuracy of this binary classification even as much as a few percent has high importance. Neural Gas Networks (NGN) is a fast, unsupervised algorithm that could…

Image and Video Processing · Electrical Eng. & Systems 2023-01-31 S. Muhammad Hossein Mousavi

Prostate cancer is a major cause of cancer-related deaths in men, where early detection greatly improves survival rates. Although MRI-TRUS fusion biopsy offers superior accuracy by combining MRI's detailed visualization with TRUS's…

Cancer detection is one of the key research topics in the medical field. Accurate detection of different cancer types is valuable in providing better treatment facilities and risk minimization for patients. This paper deals with the…

Quantitative Methods · Quantitative Biology 2022-05-31 Yasamin Kowsari , Sanaz Nakhodchi , Davoud Gholamiangonabadi

Phase microscopy is an invaluable tool in the biosciences and in clinical diagnostics. The sensitivity of current phase microscopy techniques is optimized for one specific mean phase value and varies significantly across a given sample.…

Optics · Physics 2019-08-30 Thomas Juffmann , Andrés de los Ríos Sommer , Sylvain Gigan

This work demonstrates an application of near field indirect microwave holography for the detection of malignant tissues in the human breast in an effective way. The holograms are recorded by two directive antennas aligned along each…

Ultrasound (US) is widely used for clinical imaging applications thanks to its real-time and non-invasive nature. However, its lesion detectability is often limited in many applications due to the phase aberration artefact caused by…

Image and Video Processing · Electrical Eng. & Systems 2022-02-18 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

Breast cancer is in the most common malignant tumor in women. It accounted for 30% of new malignant tumor cases. Although the incidence of breast cancer remains high around the world, the mortality rate has been continuously reduced. This…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Liuhua Zhang

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

Parkinsons disease (PD) is considered one of the most frequent neurological diseases in the world. There is a need to study the early and efficient biomarkers of Parkinsons, such as changes in structural disorders like DNA and chromatin,…

Neurofibromatosis Type 1 is a genetic disorder characterized by the development of neurofibromas (NFs), which exhibit significant variability in size, morphology, and anatomical location. Accurate and automated segmentation of these tumors…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Georgii Kolokolnikov , Marie-Lena Schmalhofer , Lennart Well , Said Farschtschi , Victor-Felix Mautner , Inka Ristow , Rene Werner

As Kaplan-Meier (KM) analysis is limited to single unidirectional endpoints, most advanced cancer randomized clinical trials (RCTs) are powered for either progression free survival (PFS) or overall survival (OS). This discards efficacy…

Methodology · Statistics 2024-06-25 Utkarsh Chauhan , Daylen Mackey , John R. Mackey

Understanding the nanoscale structural changes can provide the physical state of cells/tissues. It has been now shown that increases in nanoscale structural alterations are associated with the progress of carcinogenesis in most of the…

Biological Physics · Physics 2019-09-09 Prakash Adhikari , Mehedi Hasan , Vijayalakshmi Sridhar , Debarshi Roy , Prabhakar Pradhan

Molecular phenotyping is central in cancer precision medicine, but remains costly and standard methods only provide a tumour average profile. Microscopic morphological patterns observable in histopathology sections from tumours are…

Image and Video Processing · Electrical Eng. & Systems 2020-09-21 Yinxi Wang , Kimmo Kartasalo , Masi Valkonen , Christer Larsson , Pekka Ruusuvuori , Johan Hartman , Mattias Rantalainen