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In medical image analysis, regression plays a critical role in computer-aided diagnosis. It enables quantitative measurements such as age prediction from structural imaging, cardiac function quantification, and molecular measurement from…
Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two…
Accurate segmentation of laryngo-pharyngeal tumors is crucial for precise diagnosis and effective treatment planning. However, traditional single-modality imaging methods often fall short of capturing the complex anatomical and pathological…
Federated learning (FL) based magnetic resonance (MR) image reconstruction can facilitate learning valuable priors from multi-site institutions without violating patient's privacy for accelerating MR imaging. However, existing methods rely…
Accurate modeling of cognitive decline in Alzheimer's disease is essential for early stratification and personalized management. While tabular predictors provide robust markers of global risk, their ability to capture subtle brain changes…
Brain transcriptomics provides insights into the molecular mechanisms by which the brain coordinates its functions and processes. However, existing multimodal methods for predicting Alzheimer's disease (AD) primarily rely on imaging and…
Advances in deep learning (DL)-based models for brain image analysis have significantly enhanced the accuracy of Alzheimer's disease (AD) diagnosis, allowing for more timely interventions. Despite these advancements, most current DL models…
The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…
The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…
Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby…
Accurately detecting Alzheimer's disease (AD) and predicting mini-mental state examination (MMSE) score are important tasks in elderly health by magnetic resonance imaging (MRI). Most of the previous methods on these two tasks are based on…
Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…
Multimodal learning aims to imitate human beings to acquire complementary information from multiple modalities for various downstream tasks. However, traditional aggregation-based multimodal fusion methods ignore the inter-modality…
Deep learning approaches, together with neuroimaging techniques, play an important role in psychiatric disorders classification. Previous studies on psychiatric disorders diagnosis mainly focus on using functional connectivity matrices of…
This paper presents a general framework for obtaining interpretable multivariate discriminative models that allow efficient statistical inference for neuroimage analysis. The framework, termed generative discriminative machine (GDM),…
Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…
Alzheimer's disease (AD) is one of the most common public health issues the world is facing today. This disease has a high prevalence primarily in the elderly accompanying memory loss and cognitive decline. AD detection is a challenging…
Cognitive impairment detection through spontaneous speech is a promising avenue for early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI), where timely intervention can significantly improve patient outcomes. The…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely impairs cognitive function and quality of life. Timely intervention in AD relies heavily on early and precise diagnosis, which remains challenging due to the…
Alzheimer's Disease (AD) is marked by significant inter-individual variability in its progression, complicating accurate prognosis and personalized care planning. This heterogeneity underscores the critical need for predictive models…