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Related papers: Peristaltic pumping in sub-wavelength channels

200 papers

Peristaltic pumping is hypothesized to drive fluid transport in several physiological systems, including cerebrospinal fluid flow through cerebral perivascular spaces (PVSs). Cerebral PVSs are unique in the context of peristaltic pumping…

Fluid Dynamics · Physics 2026-05-28 Shahaf Ella Salach , Ron Shnapp

A novel approach is adopted to model cerebrospinal fluid (CSF) flow in human perivascular spaces (PVSs) surrounding brain-penetrating arteries. It is proposed that the outer PVS boundary oscillates due to brain pulsations and the arterial…

Fluid Dynamics · Physics 2025-10-24 Gregory Holba , James P. Hague , Nigel Hoggard , Marc Pradas

Two-dimensional laminar flow of a viscous fluid induced by peristalsis due to a moving wall wave has been studied previously for a rectangular channel, a circular tube, and a concentric circular annulus. Here we study peristaltic flow in a…

Fluid Dynamics · Physics 2020-07-30 J. Brennen Carr , John H. Thomas , Jia Liu , Jessica K. Shang

Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to play a key role in brain solute transport and clearance. While various drivers for pulsatile flow, such as cardiac or respiratory pulsations, are…

Fluid Dynamics · Physics 2023-10-05 Ingeborg G. Gjerde , Marie E. Rognes , Antonio L. Sanchez

Previous studies on peristalsis, the pumping of fluid along a channel by wave-like displacements of the channel walls, have shown that the elastic properties of the channel and the peristaltic wave shape can influence the flow rate.…

Fluid Dynamics · Physics 2025-08-12 Avery Trevino , Thomas R. Powers , Roberto Zenit , Mauro Rodriguez

Flow of cerebrospinal fluid in perivascular spaces is a key mechanism underlying brain transport and clearance. In this paper, we present a mathematical and numerical formalism for reduced models of pulsatile viscous fluid flow in networks…

Fluid Dynamics · Physics 2021-11-25 Cécile Daversin-Catty , Ingeborg G. Gjerde , Marie E. Rognes

The flow of cerebrospinal fluid through the perivascular spaces of the brain is believed to play a crucial role in eliminating toxic waste proteins. While the driving forces of this flow have been enigmatic, experiments have shown that…

Analysis of PDEs · Mathematics 2024-01-02 Ingeborg G. Gjerde , Miroslav Kuchta , Marie E. Rognes , Barbara Wohlmuth

The paper deals with a theoretical investigation of the peristaltic transport of a physiological fluid in a porous asymmetric channel under the action of a magnetic field. The stream function, pressure gradient and axial velocity are…

Fluid Dynamics · Physics 2010-06-04 J. C. Misra , S. Maiti , G. C. Shit

Immersed nonlinear elements are prevalent in biological systems that require a preferential flow direction, such as the venous and the lymphatic system. We investigate here a certain class of models where the fluid is driven by peristaltic…

Fluid Dynamics · Physics 2024-11-20 Aaron Winn , Eleni Katifori

Of concern in this paper is an investigation of peristaltic transport of a physiological fluid in an asymmetric channel under long wave length and low-Reynolds number assumptions. The flow is assumed to be incompressible, viscous,…

Fluid Dynamics · Physics 2010-07-07 G. C. Shit , M. Roy , E. Y. K. Ng

Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…

Neurons and Cognition · Quantitative Biology 2025-02-13 Xinglin Zeng , Yiran Li , Lin Hua , Ruoxi Lu , Lucas Lemos Franco , Peter Kochunov , Shuo Chen , John A Detre , Ze Wang

Peristalsis is the driving mechanism behind a broad array of biological and engineered flows. In peristaltic pumping, a wave-like contraction of the tube wall produces local changes in volume which induce flow. Net flow arises due to…

Fluid Dynamics · Physics 2025-10-29 Aaron Winn , Eleni Katifori

Low Reynolds number flow near a poroelastic interface can be found across scales in biological and engineered systems. We develop a 2D model of peristaltic flow confined under a poroelastic solid. In this geometry, the lower boundary is an…

Fluid Dynamics · Physics 2026-04-07 Avery Trevino , Roberto Zenit , Mauro Rodriguez

The dynamic flow of cerebrospinal fluid (CSF) in brain ventricles exhibits flow features on several scales, both spatially and temporally. Most analysis of this complex flow and the accompanying transport has used instantaneous (Eulerian)…

Fluid Dynamics · Physics 2026-03-20 Halvor Herlyng , Shawn C. Shadden

Cerebrospinal fluid (CSF) plays a pivotal role in normal functioning of Brain. Intracranial compartments such as blood, brain and CSF are incompressible in nature. Therefore, if a volume imbalance in one of the aforenoted compartments is…

Numerical Analysis · Mathematics 2021-02-22 Muhammad Uzair-Ul-Haq , Ali Ahmed , Zartasha Mustansar , Arslan Shaukat , Lee Margetts , Asim Waris , Faizan Nadeem

This paper addresses the pulsating motion of cerebrospinal fluid in the aqueduct of Sylvius, a slender canal connecting the third and fourth ventricles of the brain. Specific attention is given to the relation between the instantaneous…

Fluid Dynamics · Physics 2022-01-20 S. Sincomb , W. Coenen , A. L. Sánchez , J. C. Lasheras

Numerous mathematical models have emerged in the medical literature over the past two decades attempting to characterize the pressure and volume dynamics the central nervous system compartment. These models have been used to study he…

Numerical Analysis · Mathematics 2025-10-20 James M. Drake , Sivabal Sivaloganathan , Guiseppe Tenti

The paper is devoted to a study of the peristaltic motion of blood in the micro-circulatory system. The vessel is considered to be of varying cross-section. The progressive peristaltic waves are taken to be of sinusoidal nature. Blood is…

Fluid Dynamics · Physics 2012-12-17 J. C. Misra , S. Maiti

Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently…

Computational Physics · Physics 2020-06-23 Hakan Başağaoğlu , Justin Blount , Sauro Succi , Christopher J. Freitas

This paper considers particle propagation in a cylindrical molecular communication channel, e.g. a simplified model of a blood vessel. Emitted particles are influenced by diffusion, flow, and a vertical force induced e.g. by gravity or…

Computational Physics · Physics 2019-02-26 Maximilian Schäfer , Wayan Wicke , Rudolf Rabenstein , Robert Schober
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