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The ab initio calculation of exact quantum reaction rate constants comes at a high cost due to the required dynamics of reactants on multidimensional potential energy surfaces. In turn, this impedes the rapid design of the kinetics for…

Chemical Physics · Physics 2020-09-23 Evan Komp , Stéphanie Valleau

Inferring parameters of macro-kinetic growth models, typically represented by Ordinary Differential Equations (ODE), from the experimental data is a crucial step in bioprocess engineering. Conventionally, estimates of the parameters are…

Machine Learning · Computer Science 2023-12-07 Maxim Borisyak , Stefan Born , Peter Neubauer , Mariano Nicolas Cruz-Bournazou

The discrete chemical master equation (dCME) provides a fundamental framework for studying stochasticity in mesoscopic networks. Because of the multi-scale nature of many networks where reaction rates have large disparity, directly solving…

Quantitative Methods · Quantitative Biology 2017-07-27 Youfang Cao , Anna Terebus , Jie Liang

Tin (Sn) plays a crucial role in studying the dynamic mechanical responses of ductile metals under shock loading. Atomistic simulations serves to unveil the nano-scale mechanisms for critical behaviors of dynamic responses. However,…

Materials Science · Physics 2025-05-20 Yixin Chen , Xiaoyang Wang , Wanghui Li , Mohan Chen , Han Wang

Neural networks are one tool for approximating non-linear differential equations used in scientific computing tasks such as surrogate modeling, real-time predictions, and optimal control. PDE foundation models utilize neural networks to…

Machine Learning · Computer Science 2025-02-11 Elisa Negrini , Yuxuan Liu , Liu Yang , Stanley J. Osher , Hayden Schaeffer

This research gauges the ability of deep reinforcement learning (DRL) techniques to assist the control of conjugate heat transfer systems governed by the coupled Navier--Stokes and heat equations. It uses a novel, "degenerate" version of…

Fluid Dynamics · Physics 2021-03-25 Elie Hachem , Hassan Ghraieb , Jonathan Viquerat , Aurélien Larcher , Philippe Meliga

Owing to the remarkable development of deep learning technology, there have been a series of efforts to build deep learning-based climate models. Whereas most of them utilize recurrent neural networks and/or graph neural networks, we design…

Machine Learning · Computer Science 2021-11-12 Jeehyun Hwang , Jeongwhan Choi , Hwangyong Choi , Kookjin Lee , Dongeun Lee , Noseong Park

The development of machine learning sheds new light on the problem of statistical thermodynamics in multicomponent alloys. However, a data-driven approach to construct the effective Hamiltonian requires sufficiently large data sets, which…

Materials Science · Physics 2020-01-01 Xianglin Liu , Jiaxin Zhang , Markus Eisenbach , Yang Wang

This work presents a physics-based machine learning framework to predict and analyze oxides of nitrogen (NOx) emissions from compression-ignition engine-powered vehicles using on-board diagnostics (OBD) data as input. Accurate NOx…

Machine Learning · Computer Science 2025-03-10 Harish Panneer Selvam , Bharat Jayaprakash , Yan Li , Shashi Shekhar , William F. Northrop

The fast simulation of dynamical systems is a key challenge in many scientific and engineering applications, such as weather forecasting, disease control, and drug discovery. With the recent success of deep learning, there is increasing…

Machine Learning · Computer Science 2024-10-02 Zezheng Song , Jiaxin Yuan , Haizhao Yang

Scientific machine learning is an emerging field that broadly describes the combination of scientific computing and machine learning to address challenges in science and engineering. Within the context of differential equations, this has…

Machine Learning · Computer Science 2026-04-03 Laurens R. Lueg , Victor Alves , Daniel Schicksnus , John R. Kitchin , Carl D. Laird , Lorenz T. Biegler

Path-like collective variables can be very effective for accurately modeling complex biomolecular processes in molecular dynamics simulations. Recently, we introduced DeepLNE, a machine learning-based path-like CV that provides a…

Chemical Physics · Physics 2024-07-08 Thorben Fröhlking , Valerio Rizzi , Simone Aureli , Francesco Luigi Gervasio

Exploiting low-precision computations has become a standard strategy in deep learning to address the growing computational costs imposed by ever larger models and datasets. However, naively performing all computations in low precision can…

Machine Learning · Computer Science 2026-05-01 Elena Celledoni , Brynjulf Owren , Lars Ruthotto , Tianjiao Nicole Yang

Recent years have witnessed a growth in mathematics for deep learning--which seeks a deeper understanding of the concepts of deep learning with mathematics and explores how to make it more robust--and deep learning for mathematics, where…

Machine Learning · Computer Science 2023-10-31 Derick Nganyu Tanyu , Jianfeng Ning , Tom Freudenberg , Nick Heilenkötter , Andreas Rademacher , Uwe Iben , Peter Maass

Fuels with high-knock resistance enable modern spark-ignition engines to achieve high efficiency and thus low CO2 emissions. Identification of molecules with desired autoignition properties indicated by a high research octane number and a…

We introduce a novel algorithm for gradient-based optimization of stochastic objective functions. The method may be seen as a variant of SGD with momentum equipped with an adaptive learning rate automatically adjusted by an 'energy'…

Optimization and Control · Mathematics 2022-03-24 Hailiang Liu , Xuping Tian

Differential equations (DE) constrained optimization plays a critical role in numerous scientific and engineering fields, including energy systems, aerospace engineering, ecology, and finance, where optimal configurations or control…

Machine Learning · Computer Science 2024-10-03 Vincenzo Di Vito , Mostafa Mohammadian , Kyri Baker , Ferdinando Fioretto

In this paper, we propose a deep learning-based method, deep Euler method (DEM) to solve ordinary differential equations. DEM significantly improves the accuracy of the Euler method by approximating the local truncation error with deep…

Numerical Analysis · Mathematics 2020-03-24 Xing Shen , Xiaoliang Cheng , Kewei Liang

Autoignition delay times have been measured in a rapid compression machine at Lille at temperatures after compression from 630 to 840 K, pressures from 8 to 14 bar, \Phi = 1 and for a iso octane/1 hexene mixture containing 82% iso-octane…

We combine density-functional tight-binding (DFTB) with deep tensor neural networks (DTNN) to maximize the strengths of both approaches in predicting structural, energetic, and vibrational molecular properties. The DTNN is used to learn a…

Chemical Physics · Physics 2020-06-19 Martin Stöhr , Leonardo Medrano Sandonas , Alexandre Tkatchenko
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