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Quantitative photoacoustic computed tomography (qPACT) is an emerging medical imaging modality that carries the promise of high-contrast, fine-resolution imaging of clinically relevant quantities like hemoglobin concentration and…

Medical Physics · Physics 2024-10-15 Evan Scope Crafts , Mark A. Anastasio , Umberto Villa

This work studies the inverse problem of photoacoustic tomography (more precisely, the acoustic subproblem) as the identification of a space-dependent source parameter. The model consists of a wave equation involving a time-fractional…

Numerical Analysis · Mathematics 2025-04-29 Phuoc-Truong Huynh , Barbara Kaltenbacher

The standard approach for photoacoustic imaging with variable speed of sound is time reversal, which consists in solving a well-posed final-boundary value problem for the wave equation backwards in time. This paper investigates the…

Optimization and Control · Mathematics 2016-03-17 Zakaria Belhachmi , Thomas Glatz , Otmar Scherzer

Numerical approximation of quantum states via convex combinations of states with positive partial transposes (bi-PPT state) in multipartite systems constitutes a fundamental challenge in quantum information science. We reformulate this…

Mathematical Physics · Physics 2025-09-24 Jingwen Fan , Deren Han , Lin Chen

In photoacoustic imaging the objective is to determine the optical properties of biological tissue from boundary measurement of the generated acoustic wave. Here, we propose a restriction to piecewise constant media parameters. Precisely we…

Analysis of PDEs · Mathematics 2024-07-09 Yavar Kian , Faouzi Triki

Photoacoustic tomography is a contrast agent-free imaging technique capable of visualizing blood vessels and tumor-associated vascularization in breast tissue. While sophisticated breast imaging systems have been recently developed, there…

The goal of \emph{photoacoustic tomography} (PAT) is to estimate an \emph{initial pressure function} $\varphi$ from pressure data measured at a boundary surrounding the object of interest. This paper is concerned with a time reversal method…

Analysis of PDEs · Mathematics 2014-02-19 Richard Kowar

Electrical Impedance Tomography (EIT) is a powerful imaging technique with diverse applications, e.g., medical diagnosis, industrial monitoring, and environmental studies. The EIT inverse problem is about inferring the internal conductivity…

Machine Learning · Computer Science 2023-10-31 Derick Nganyu Tanyu , Jianfeng Ning , Andreas Hauptmann , Bangti Jin , Peter Maass

The image reconstruction of partially coherent light is interpreted as the quantum state reconstruction. The efficient method based on maximum-likelihood estimation is proposed to acquire information from registered intensity measurements…

Optics · Physics 2011-07-22 M. Jezek , Z. Hradil

Quantum tomography is a process of quantum state reconstruction using data from multiple measurements. An essential goal for a quantum tomography algorithm is to find measurements that will maximize the useful information about an unknown…

Quantum Physics · Physics 2020-08-05 A. D. Moiseevskiy , G. I. Struchalin , S. S. Straupe , S. P. Kulik

PAT is the best-known example of a hybrid imaging method. In this article, we define a Radon-type transform arising in a version of PAT that uses integrating circle detectors and describe how the Radon transform integrating over all circles…

Functional Analysis · Mathematics 2014-12-09 Sunghwan Moon

Increasing the imaging speed is a central aim in photoacoustic tomography. This issue is especially important in the case of sequential scanning approaches as applied for most existing optical detection schemes. In this work we address this…

Numerical Analysis · Mathematics 2016-11-23 Markus Haltmeier , Thomas Berer , Sunghwan Moon , Peter Burgholzer

Optical absorption is a primary, label-defining contrast across biology, pathology, and materials science, yet three-dimensional quantitative absorption imaging has remained largely inaccessible to the brightfield microscopes used in…

In the mathematical analysis of photoacoustic imaging, it is usually assumed that the acoustic pressure (Dirichlet data) is measured on a detection surface. However, actual ultrasound detectors gather data of a different type. In this…

Analysis of PDEs · Mathematics 2020-07-01 Sebastian Acosta

An inverse problem of the determination of an initial condition in a hyperbolic equation from the lateral Cauchy data is considered. This problem has applications to the thermoacoustic tomography, as well as to linearized coefficient…

Mathematical Physics · Physics 2007-12-04 Michael V Klibanov , Sergey I Kabanikhin , Dmitriy V Nechaev , Andrey V Kuzhuget

In this paper, we consider two types of damped wave equations: the weakly damped equation and the strongly damped equation. We recover the initial velocity from the trace of the solution on a space-time cylinder. This inverse problem is…

Analysis of PDEs · Mathematics 2024-04-30 Seongyeon Kim , Sunghwan Moon , Ihyeok Seo

Quantitative tissue information, like the light scattering properties, is considered as a key player in the detection of cancerous cells in medical diagnosis. A promising method to obtain these data is optical coherence tomography (OCT). In…

Numerical Analysis · Mathematics 2023-06-21 Leopold Veselka , Peter Elbau , Leonidas Mindrinos , Lisa Krainz , Wolfgang Drexler

Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…

Medical Physics · Physics 2024-02-23 Leopold Veselka , Lisa Krainz , Leonidas Mindrinos , Wolfgang Drexler , Peter Elbau

Image reconstruction in photoacoustic tomography relies on an accurate knowledge of the speed of sound in the target. However, the speed of sound distribution is not generally known, which may result in artefacts in the reconstructed…

Medical Physics · Physics 2025-11-06 Miika Suhonen , Felix Lucka , Aki Pulkkinen , Simon Arridge , Ben Cox , Tanja Tarvainen

Iterative image reconstruction algorithms for optoacoustic tomography (OAT), also known as photoacoustic tomography, have the ability to improve image quality over analytic algorithms due to their ability to incorporate accurate models of…

Analysis of PDEs · Mathematics 2015-06-05 Kun wang , Richard Su , Alexander A. Oraevsky , Mark A. Anastasio