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Traumatic Brain Injury (TBI) poses a significant global public health challenge, contributing to high morbidity and mortality rates and placing a substantial economic burden on healthcare systems worldwide. The diagnosis of TBI relies on…

Image and Video Processing · Electrical Eng. & Systems 2024-01-12 Hanem Ellethy , Shekhar S. Chandra , Viktor Vegh

Existing methods to characterise the evolving condition of traumatic brain injury (TBI) patients in the intensive care unit (ICU) do not capture the context necessary for individualising treatment. Here, we integrate all heterogenous data…

Traumatic brain injury (TBI) presents a significant public health challenge, often resulting in mortality or lasting disability. Predicting outcomes such as mortality and Functional Status Scale (FSS) scores can enhance treatment strategies…

Machine Learning · Computer Science 2024-10-29 Lucas Steinmetz , Shivam Maheshwari , Garik Kazanjian , Abigail Loyson , Tyler Alexander , Venkat Margapuri , C. Nataraj

The accurate prognosis for traumatic brain injury (TBI) patients is difficult yet essential to inform therapy, patient management, and long-term after-care. Patient characteristics such as age, motor and pupil responsiveness, hypoxia and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Margherita Rosnati , Eyal Soreq , Miguel Monteiro , Lucia Li , Neil S. N. Graham , Karl Zimmerman , Carlotta Rossi , Greta Carrara , Guido Bertolini , David J. Sharp , Ben Glocker

Patients with traumatic brain injury (TBI) often experience pathological increases in intracranial pressure (ICP), leading to intracranial hypertension (tIH), a common and serious complication. Early warning of an impending rise in ICP…

Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction…

Quantitative Methods · Quantitative Biology 2025-05-23 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Traumatic brain injury (TBI) is intrinsically heterogeneous, and typical clinical outcome measures like the Glasgow Coma Scale complicate this diversity. The large variability in severity and patient outcomes render it difficult to link…

Understanding the association between injury severity and patients' potential for recovery is crucial to providing better care for patients with traumatic brain injury (TBI). Estimation of this relationship requires clinical information on…

Methodology · Statistics 2020-05-19 Mingyang Shan , Kali Thomas , Roee Gutman

Traumatic brain injury (TBI) is a complex injury that is hard to predict and diagnose, with many studies focused on associating head kinematics to brain injury risk. Recently, there has been a push towards using computationally expensive…

Traumatic Brain Injuries (TBIs) resulting from Road Traffic Crashes (RTCs) can have fatal and disabling effects on patients. In this study, we evaluated the TBIs outcomes of patients involved in RTCs and identify key contributing factors…

Applications · Statistics 2024-11-05 Azka Rodoshi Oishi , Md Jamil Ahsan , Azka Sejuti , B M Tazbiul Hassan Anik

Mild traumatic brain injury (mTBI) is a growing public health problem with an estimated incidence of one million people annually in US. Neurocognitive tests are used to both assess the patient condition and to monitor the patient progress.…

Computer Vision and Pattern Recognition · Computer Science 2018-02-16 Shervin Minaee , Siyun Wang , Yao Wang , Sohae Chung , Xiuyuan Wang , Els Fieremans , Steven Flanagan , Joseph Rath , Yvonne W. Lui

Despite the impressive advancements achieved using deep-learning for functional brain activity analysis, the heterogeneity of functional patterns and scarcity of imaging data still pose challenges in tasks such as prediction of future onset…

Image and Video Processing · Electrical Eng. & Systems 2023-12-25 Wenhui Cui , Haleh Akrami , Ganning Zhao , Anand A. Joshi , Richard M. Leahy

Traumatic Brain Injury (TBI) presents a broad spectrum of clinical presentations and outcomes due to its inherent heterogeneity, leading to diverse recovery trajectories and varied therapeutic responses. While many studies have delved into…

Machine Learning · Computer Science 2024-08-22 Hamid Ghaderi , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Constantin Ulrich , Tassilo Wald , Fabian Isensee , Klaus H. Maier-Hein

Background: Ventilator-associated pneumonia (VAP) in traumatic brain injury (TBI) patients poses a significant mortality risk and imposes a considerable financial burden on patients and healthcare systems. Timely detection and…

Machine Learning · Computer Science 2024-08-05 Negin Ashrafi , Armin Abdollahi , Maryam Pishgar

Brain network analysis for traumatic brain injury (TBI) patients is critical for its consciousness level assessment and prognosis evaluation, which requires the segmentation of certain consciousness-related brain regions. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2022-08-15 Xiangyu Zhao , Di Zang , Sheng Wang , Zhenrong Shen , Kai Xuan , Zeyu Wei , Zhe Wang , Ruizhe Zheng , Xuehai Wu , Zheren Li , Qian Wang , Zengxin Qi , Lichi Zhang

In this paper, we introduce a new dataset in the medical field of Traumatic Brain Injury (TBI), called TBI-IT, which includes both electronic medical records (EMRs) and head CT images. This dataset is designed to enhance the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Jie Li , Jiaying Wen , Tongxin Yang , Fenglin Cai , Miao Wei , Zhiwei Zhang , Li Jiang

Brain stroke remains one of the principal causes of death and disability worldwide, yet most tabular-data prediction models still hover below the 95% accuracy threshold, limiting real-world utility. Addressing this gap, the present work…

Quantitative Methods · Quantitative Biology 2026-05-22 Yousuf Islam , Md. Jalal Uddin Chowdhury , Sumon Chandra Das

Aim: This in silico study sought to identify specific biomarkers for mild traumatic brain injury (mTBI) through the analysis of publicly available gene and miRNA databases, hypothesizing their influence on neuronal structure, axonal…

Genomics · Quantitative Biology 2025-05-02 Mahnaz Tajik , Michael D Noseworthy

When a patient is admitted to the intensive care unit (ICU) after a traumatic brain injury (TBI), an early prognosis is essential for baseline risk adjustment and shared decision making. TBI outcomes are commonly categorised by the Glasgow…

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