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We present a latent variable model for classification that provides a novel probabilistic interpretation of neural network softmax classifiers. We derive a variational objective to train the model, analogous to the evidence lower bound…

Machine Learning · Computer Science 2024-01-10 Shehzaad Dhuliawala , Mrinmaya Sachan , Carl Allen

Generative adversarial networks (GANs) form a generative modeling approach known for producing appealing samples, but they are notably difficult to train. One common way to tackle this issue has been to propose new formulations of the GAN…

Machine Learning · Computer Science 2020-09-01 Gauthier Gidel , Hugo Berard , Gaëtan Vignoud , Pascal Vincent , Simon Lacoste-Julien

We develop a novel probabilistic generative model based on the variational autoencoder approach. Notable aspects of our architecture are: a novel way of specifying the latent variables prior, and the introduction of an ordinality enforcing…

Machine Learning · Statistics 2018-12-20 Joel Jaskari , Jyri J. Kivinen

The core principle of Variational Inference (VI) is to convert the statistical inference problem of computing complex posterior probability densities into a tractable optimization problem. This property enables VI to be faster than several…

Machine Learning · Computer Science 2023-10-25 Ankush Ganguly , Sanjana Jain , Ukrit Watchareeruetai

Residual-based adaptive strategies are widely used in scientific machine learning but remain largely heuristic. We introduce a unifying variational framework that formalizes these methods by integrating convex transformations of the…

Machine Learning · Computer Science 2025-09-29 Juan Diego Toscano , Daniel T. Chen , Vivek Oommen , Jérôme Darbon , George Em Karniadakis

Bayesian analyses combine information represented by different terms in a joint Bayesian model. When one or more of the terms is misspecified, it can be helpful to restrict the use of information from suspect model components to modify…

Methodology · Statistics 2022-06-27 Xuejun Yu , David J. Nott , Michael Stanley Smith

Models with a large number of latent variables are often used to fully utilize the information in big or complex data. However, they can be difficult to estimate using standard approaches, and variational inference methods are a popular…

Methodology · Statistics 2021-04-20 Rubén Loaiza-Maya , Michael Stanley Smith , David J. Nott , Peter J. Danaher

Advances in generative modeling based on GANs has motivated the community to find their use beyond image generation and editing tasks. In particular, several recent works have shown that GAN representations can be re-purposed for…

Computer Vision and Pattern Recognition · Computer Science 2022-05-02 Oindrila Saha , Zezhou Cheng , Subhransu Maji

We propose a probabilistic framework for developing computational models of biological neural systems. In this framework, physiological recordings are viewed as discrete-time partial observations of an underlying continuous-time stochastic…

Neurons and Cognition · Quantitative Biology 2026-02-10 Ahmed ElGazzar , Marcel van Gerven

Protein fitness optimization involves finding a protein sequence that maximizes desired quantitative properties in a combinatorially large design space of possible sequences. Recent advances in steering protein generative models (e.g.,…

Biomolecules · Quantitative Biology 2025-10-22 Jason Yang , Wenda Chu , Daniel Khalil , Raul Astudillo , Bruce J. Wittmann , Frances H. Arnold , Yisong Yue

We introduce a novel one-parameter variational objective that lower bounds the data evidence and enables the estimation of approximate fractional posteriors. We extend this framework to hierarchical construction and Bayes posteriors,…

Machine Learning · Computer Science 2026-03-31 Kian Ming A. Chai , Edwin V. Bonilla

We discuss a general technique that can be used to form a differentiable bound on the optima of non-differentiable or discrete objective functions. We form a unified description of these methods and consider under which circumstances the…

Machine Learning · Statistics 2012-12-21 Joe Staines , David Barber

Many problems in machine learning are naturally expressed in the language of undirected graphical models. Here, we propose black-box learning and inference algorithms for undirected models that optimize a variational approximation to the…

Machine Learning · Computer Science 2017-11-20 Volodymyr Kuleshov , Stefano Ermon

In this paper we consider the problem of learning variational models in the context of supervised learning via risk minimization. Our goal is to provide a deeper understanding of the two approaches of learning of variational models via…

Machine Learning · Statistics 2023-09-07 Christoph Brauer , Niklas Breustedt , Timo de Wolff , Dirk A. Lorenz

Deep learning approaches process data in a layer-by-layer way with intermediate (or latent) features. We aim at designing a general solution to optimize the latent manifolds to improve the performance on classification, segmentation,…

Machine Learning · Computer Science 2025-06-03 Yida Wang , David Joseph Tan , Nassir Navab , Federico Tombari

Evolutionary model merging provides a powerful framework for the automated, training-free composition of LLMs through parameter-space search. However, existing methods predominantly rely on stochastic, hand-crafted operators that overlook…

Neural and Evolutionary Computing · Computer Science 2026-05-29 Tao Jiang , Xinmeng Yu , Chenhao Yi , Yiling Wu , Yan Li , Ran Cheng , Dongmei Jiang , Jianguo Zhang

We study the problem of learning latent variables in Gaussian graphical models. Existing methods for this problem assume that the precision matrix of the observed variables is the superposition of a sparse and a low-rank component. In this…

Machine Learning · Statistics 2017-07-12 Mohammadreza Soltani , Chinmay Hegde

Reliable training of generative adversarial networks (GANs) typically require massive datasets in order to model complicated distributions. However, in several applications, training samples obey invariances that are \textit{a priori}…

The effective planning and allocation of resources in modern breeding programs is a complex task. Breeding program design and operational management have a major impact on the success of a breeding program and changing parameters such as…

Quantitative Methods · Quantitative Biology 2024-07-25 Azadeh Hassanpour , Johannes Geibel , Henner Simianer , Antje Rohde , Torsten Pook

Variational approximation methods have proven to be useful for scaling Bayesian computations to large data sets and highly parametrized models. Applying variational methods involves solving an optimization problem, and recent research in…

Methodology · Statistics 2017-01-13 Victor M. -H. Ong , David J. Nott , Michael S. Smith
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