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We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

Low-light image enhancement is a classical computer vision problem aiming to recover normal-exposure images from low-light images. However, convolutional neural networks commonly used in this field are good at sampling low-frequency local…

Computer Vision and Pattern Recognition · Computer Science 2022-09-19 Yunliang Zhuang , Zhuoran Zheng , Chen Lyu

We aim to generate high resolution shallow depth-of-field (DoF) images from a single all-in-focus image with controllable focal distance and aperture size. To achieve this, we propose a novel neural network model comprised of a depth…

Computer Vision and Pattern Recognition · Computer Science 2018-10-19 Lijun Wang , Xiaohui Shen , Jianming Zhang , Oliver Wang , Zhe Lin , Chih-Yao Hsieh , Sarah Kong , Huchuan Lu

Low-light image enhancement aims to restore the visibility of images captured by visual sensors in dim environments by addressing their inherent signal degradations, such as luminance attenuation and structural corruption. Although numerous…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Yicui Shi , Yuhan Chen , Xiangfei Huang , Zhenguo Wang , Wenxuan Yu , Ying Fang

We propose a compact snapshot monocular depth estimation technique that relies on an engineered point spread function (PSF). Traditional approaches used in microscopic super-resolution imaging such as the Double-Helix PSF (DHPSF) are…

Image and Video Processing · Electrical Eng. & Systems 2022-08-05 Bhargav Ghanekar , Vishwanath Saragadam , Dushyant Mehra , Anna-Karin Gustavsson , Aswin Sankaranarayanan , Ashok Veeraraghavan

Wide-angle portraits often enjoy expanded views. However, they contain perspective distortions, especially noticeable when capturing group portrait photos, where the background is skewed and faces are stretched. This paper introduces the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-29 Jing Tan , Shan Zhao , Pengfei Xiong , Jiangyu Liu , Haoqiang Fan , Shuaicheng Liu

Deep learning methods have witnessed the great progress in image restoration with specific metrics (e.g., PSNR, SSIM). However, the perceptual quality of the restored image is relatively subjective, and it is necessary for users to control…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Wei Wang , Ruiming Guo , Yapeng Tian , Wenming Yang

Volumetric imaging by fluorescence microscopy is often limited by anisotropic spatial resolution from inferior axial resolution compared to the lateral resolution. To address this problem, here we present a deep-learning-enabled…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Hyoungjun Park , Myeongsu Na , Bumju Kim , Soohyun Park , Ki Hean Kim , Sunghoe Chang , Jong Chul Ye

Recently, Deep Unfolding Networks (DUNs) have achieved impressive reconstruction quality in the field of image Compressive Sensing (CS) by unfolding iterative optimization algorithms into neural networks. The reconstruction quality of DUNs…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Chen Liao , Yan Shen , Dan Li , Zhongli Wang

Large-scale astronomical surveys can capture numerous images of celestial objects, including galaxies and nebulae. Analysing and processing these images can reveal intricate internal structures of these objects, allowing researchers to…

Instrumentation and Methods for Astrophysics · Physics 2023-11-02 Peng Jia , Jiameng Lv , Runyu Ning , Yu Song , Nan Li , Kaifan Ji , Chenzhou Cui , Shanshan Li

Image deblurring is a classical computer vision problem that aims to recover a sharp image from a blurred image. To solve this problem, existing methods apply the Encode-Decode architecture to design the complex networks to make a good…

Image and Video Processing · Electrical Eng. & Systems 2021-10-13 Wenbin Zou , Mingchao Jiang , Yunchen Zhang , Liang Chen , Zhiyong Lu , Yi Wu

Optical focusing at depths in tissue is the Holy Grail of biomedical optics that may bring revolutionary advancement to the field. Wavefront shaping is a widely accepted approach to solve this problem, but most implementations thus far have…

Applied Physics · Physics 2019-09-04 Yunqi Luo , Suxia Yan , Huanhao Li , Puxiang Lai , Yuanjin Zheng

We propose a dual-domain cascade of U-nets (i.e. a "W-net") operating in both the spatial frequency and image domains to enhance low-dose CT (LDCT) images without the need for proprietary x-ray projection data. The central slice theorem…

Image and Video Processing · Electrical Eng. & Systems 2020-05-28 Kevin J. Chung , Roberto Souza , Richard Frayne , Ting-Yim Lee

Pansharpening refers to the fusion of a panchromatic image with a high spatial resolution and a multispectral image with a low spatial resolution, aiming to obtain a high spatial resolution multispectral image. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Tian-Jing Zhang , Liang-Jian Deng , Ting-Zhu Huang , Jocelyn Chanussot , Gemine Vivone

Fluorescent molecules are versatile nanoscale emitters that enable detailed observations of biophysical processes with nanoscale resolution. Because they are well-approximated as electric dipoles, imaging systems can be designed to…

Optics · Physics 2024-03-26 Tingting Wu , Matthew D. Lew

Change detection in remote sensing imagery plays a vital role in various engineering applications, such as natural disaster monitoring, urban expansion tracking, and infrastructure management. Despite the remarkable progress of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Xiaoyang Zhang , Guodong Fan , Guang-Yong Chen , Zhen Hua , Jinjiang Li , Min Gan , C. L. Philip Chen

Automatic medical image segmentation has wide applications for disease diagnosing. However, it is much more challenging than natural optical image segmentation due to the high-resolution of medical images and the corresponding huge…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Ziqiang Li , Rentuo Tao , Qianrun Wu , Bin Li

Light-field microscopes are able to capture spatial and angular information of incident light rays. This allows reconstructing 3D locations of neurons from a single snap-shot.In this work, we propose a model-inspired deep learning approach…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Pingfan Song , Herman Verinaz Jadan , Carmel L. Howe , Peter Quicke , Amanda J. Foust , Pier Luigi Dragotti

Deconvolution is the most commonly used image processing method to remove the blur caused by the point-spread-function (PSF) in optical imaging systems. While this method has been successful in deblurring, it suffers from several…

Image and Video Processing · Electrical Eng. & Systems 2019-10-10 Huangxuan Zhao , Ziwen Ke , Ningbo Chen , Ke Li , Lidai Wang , Xiaojing Gong , Wei Zheng , Liang Song , Zhicheng Liu , Dong Liang , Chengbo Liu

Identifying and characterizing brain fiber bundles can help to understand many diseases and conditions. An important step in this process is the estimation of fiber orientations using Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI).…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Mateus Oliveira da Silva , Caio Pinheiro Santana , Diedre Santos do Carmo , Letícia Rittner