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Deep latent-variable models learn representations of high-dimensional data in an unsupervised manner. A number of recent efforts have focused on learning representations that disentangle statistically independent axes of variation by…

Radiogenomics is an emerging field in cancer research that combines medical imaging data with genomic data to predict patients clinical outcomes. In this paper, we propose a multivariate sparse group lasso joint model to integrate imaging…

Methodology · Statistics 2022-06-06 Tiantian Zeng , Md Selim , Jie Zhang , Arnold Stromberg , Jin Chen , Chi Wang

Real-world datasets are often biased with respect to key demographic factors such as race and gender. Due to the latent nature of the underlying factors, detecting and mitigating bias is especially challenging for unsupervised machine…

Machine Learning · Computer Science 2020-07-01 Kristy Choi , Aditya Grover , Trisha Singh , Rui Shu , Stefano Ermon

An extension of the latent class model is presented for clustering categorical data by relaxing the classical "class conditional independence assumption" of variables. This model consists in grouping the variables into inter-independent and…

Computation · Statistics 2015-10-01 Matthieu Marbac , Christophe Biernacki , Vincent Vandewalle

The ability to manipulate complex systems, such as the brain, to modify specific outcomes has far-reaching implications, particularly in the treatment of psychiatric disorders. One approach to designing appropriate manipulations is to…

Machine Learning · Statistics 2024-09-05 Austin Talbot , Corey J Keller , David E Carlson , Alex V Kotlar

Noisy labels are both inevitable and problematic in machine learning methods, as they negatively impact models' generalization ability by causing overfitting. In the context of learning with noise, the transition matrix plays a crucial role…

Machine Learning · Computer Science 2025-03-26 Jiahui Li , Tai-Wei Chang , Kun Kuang , Ximing Li , Long Chen , Jun Zhou

Person re-identification (re-id) remains challenging due to significant intra-class variations across different cameras. Recently, there has been a growing interest in using generative models to augment training data and enhance the…

Computer Vision and Pattern Recognition · Computer Science 2021-05-20 Zhedong Zheng , Xiaodong Yang , Zhiding Yu , Liang Zheng , Yi Yang , Jan Kautz

Most causal discovery algorithms find causal structure among a set of observed variables. Learning the causal structure among latent variables remains an important open problem, particularly when using high-dimensional data. In this paper,…

Machine Learning · Computer Science 2020-09-09 Jonathan D. Young , Bryan Andrews , Gregory F. Cooper , Xinghua Lu

We study the problem of learning latent variables in Gaussian graphical models. Existing methods for this problem assume that the precision matrix of the observed variables is the superposition of a sparse and a low-rank component. In this…

Machine Learning · Statistics 2017-07-12 Mohammadreza Soltani , Chinmay Hegde

Latent or unobserved phenomena pose a significant difficulty in data analysis as they induce complicated and confounding dependencies among a collection of observed variables. Factor analysis is a prominent multivariate statistical modeling…

Methodology · Statistics 2020-06-22 Armeen Taeb , Venkat Chandrasekaran

Variable selection, also known as feature selection in machine learning, plays an important role in modeling high dimensional data and is key to data-driven scientific discoveries. We consider here the problem of detecting influential…

Methodology · Statistics 2014-09-24 Bo Jiang , Jun S. Liu

Unobserved confounding is one of the main challenges when estimating causal effects. We propose a causal reduction method that, given a causal model, replaces an arbitrary number of possibly high-dimensional latent confounders with a single…

Machine Learning · Statistics 2023-02-24 Maximilian Ilse , Patrick Forré , Max Welling , Joris M. Mooij

Recommendation systems (RS) aim to provide personalized content, but they face a challenge in unbiased learning due to selection bias, where users only interact with items they prefer. This bias leads to a distorted representation of user…

Machine Learning · Computer Science 2025-06-10 Shuqiang Zhang , Yuchao Zhang , Jinkun Chen , Haochen Sui

We consider applying Bayesian Variable Selection Regression, or BVSR, to genome-wide association studies and similar large-scale regression problems. Currently, typical genome-wide association studies measure hundreds of thousands, or…

Applications · Statistics 2011-10-28 Yongtao Guan , Matthew Stephens

Generative modeling of high-dimensional data is a key problem in machine learning. Successful approaches include latent variable models and autoregressive models. The complementary strengths of these approaches, to model global and local…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Thomas Lucas , Jakob Verbeek

Convolutional neural network (CNN) and its variants have led to many state-of-art results in various fields. However, a clear theoretical understanding about them is still lacking. Recently, multi-layer convolutional sparse coding (ML-CSC)…

Machine Learning · Computer Science 2020-07-22 Zhiyang Zhang , Shihua Zhang

A standard approach for assessing the performance of partition models is to create synthetic data sets with a prespecified clustering structure, and assess how well the model reveals this structure. A common format is that subjects are…

Methodology · Statistics 2025-07-08 Michail Papathomas

Time series data is prevalent in a wide variety of real-world applications and it calls for trustworthy and explainable models for people to understand and fully trust decisions made by AI solutions. We consider the problem of building…

Machine Learning · Computer Science 2020-11-25 Tsung-Yu Hsieh , Suhang Wang , Yiwei Sun , Vasant Honavar

One important problem in genome science is to determine sets of co-regulated genes based on measurements of gene expression levels across samples, where the quantification of expression levels includes substantial technical and biological…

Applications · Statistics 2013-10-18 Chuan Gao , Christopher D Brown , Barbara E Engelhardt

Latent Class Analysis (LCA) is widely used to identify unobserved subgroups in social and behavioural sciences. A long-standing challenge for LCA is the interpretability of the latent classes, due to the high complexity of the estimated…

Methodology · Statistics 2026-05-20 Yuxuan Xu , Lea Kaufmann , Yunxiao Chen , Maria Kateri , Irini Moustaki
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