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The reuse of historical clinical trial data has significant potential to accelerate medical research and drug development. However, interoperability challenges, particularly with missing medical codes, hinders effective data integration…

Machine Learning · Computer Science 2025-03-14 Nabeel Seedat , Caterina Tozzi , Andrea Hita Ardiaca , Mihaela van der Schaar , James Weatherall , Adam Taylor

Unsupervised pretraining is an integral part of many natural language processing systems, and transfer learning with language models has achieved remarkable results in many downstream tasks. In the clinical application of medical code…

Computation and Language · Computer Science 2022-06-03 Shaoxiong Ji , Matti Hölttä , Pekka Marttinen

Background and Objective: Code assignment is of paramount importance in many levels in modern hospitals, from ensuring accurate billing process to creating a valid record of patient care history. However, the coding process is tedious and…

Computation and Language · Computer Science 2019-10-03 Jinmiao Huang , Cesar Osorio , Luke Wicent Sy

In recent years, multi-label classification problem has become a controversial issue. In this kind of classification, each sample is associated with a set of class labels. Ensemble approaches are supervised learning algorithms in which an…

Machine Learning · Computer Science 2018-01-09 Amirreza Mahdavi-Shahri , Mahboobeh Houshmand , Mahdi Yaghoobi , Mehrdad Jalali

This paper investigates novel classifier ensemble techniques for uncertainty calibration applied to various deep neural networks for image classification. We evaluate both accuracy and calibration metrics, focusing on Expected Calibration…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Michael Schulze , Nikolas Ebert , Laurenz Reichardt , Oliver Wasenmüller

The use of Electronic Health Records (EHRs) has increased dramatically in the past 15 years, as, it is considered an important source of managing data od patients. The EHRs are primary sources of disease diagnosis and demographic data of…

Machine Learning · Computer Science 2024-04-02 Bushra F. Alsaqer , Alaa F. Alsaqer , Amna Asif

Cell imaging and analysis are fundamental to biomedical research because cells are the basic functional units of life. Among different cell-related analysis, cell counting and detection are widely used. In this paper, we focus on one common…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Haoyi Liang , Aijaz Naik , Cedric L. Williams , Jaideep Kapur , Daniel S. Weller

Chemotherapeutic response of cancer cells to a given compound is one of the most fundamental information one requires to design anti-cancer drugs. Recent advances in producing large drug screens against cancer cell lines provided an…

Genomics · Quantitative Biology 2018-07-17 Mehmet Tan , Ozan Fırat Özgül , Batuhan Bardak , Işıksu Ekşioğlu , Suna Sabuncuoğlu

A large volume of research has considered the creation of predictive models for clinical data; however, much existing literature reports results using only a single source of data. In this work, we evaluate the performance of models trained…

Machine Learning · Computer Science 2018-12-07 Alistair E. W. Johnson , Tom J. Pollard , Tristan Naumann

Recent deep learning research based on Transformer model architectures has demonstrated state-of-the-art performance across a variety of domains and tasks, mostly within the computer vision and natural language processing domains. While…

Machine Learning · Computer Science 2021-11-11 Benjamin Shickel , Patrick J. Tighe , Azra Bihorac , Parisa Rashidi

Uncertainty quantification in automated image analysis is highly desired in many applications. Typically, machine learning models in classification or segmentation are only developed to provide binary answers; however, quantifying the…

The task of automatically coding the International Classification of Diseases (ICD) in the medical field has been well-established and has received much attention. Automatic coding of the ICD in the medical field has been successful in…

Computation and Language · Computer Science 2026-03-11 Xinxin You , Xien Liu , Xue Yang , Ziyi Wang , Ji Wu

Obesity is a critical global health issue driven by dietary, physiological, and environmental factors, and is strongly associated with chronic diseases such as diabetes, cardiovascular disorders, and cancer. Machine learning has emerged as…

Machine Learning · Computer Science 2026-05-11 Towhidul Islam , Md Sumon Ali

ICD(International Classification of Diseases) coding involves assigning ICD codes to patients visit based on their medical notes. Considering ICD coding as a multi-label text classification task, researchers have developed sophisticated…

Computation and Language · Computer Science 2024-10-21 Bin Zhang , Junli Wang

This technical report introduces a Named Clinical Entity Recognition Benchmark for evaluating language models in healthcare, addressing the crucial natural language processing (NLP) task of extracting structured information from clinical…

Identification of key variables such as medications, diseases, relations from health records and clinical notes has a wide range of applications in the clinical domain. n2c2 2022 provided shared tasks on challenges in natural language…

Computation and Language · Computer Science 2025-07-01 Shouvon Sarker , Xishuang Dong , Lijun Qian

Substantial increase in the use of Electronic Health Records (EHRs) has opened new frontiers for predictive healthcare. However, while EHR systems are nearly ubiquitous, they lack a unified code system for representing medical concepts.…

Machine Learning · Computer Science 2022-03-21 Kyunghoon Hur , Jiyoung Lee , Jungwoo Oh , Wesley Price , Young-Hak Kim , Edward Choi

Forecasts of the trajectory of an infectious agent can help guide public health decision making. A traditional approach to forecasting fits a computational model to structured data and generates a predictive distribution. However, human…

Existing Clinical Decision Support Systems (CDSSs) largely depend on the availability of structured patient data and Electronic Health Records (EHRs) to aid caregivers. However, in case of hospitals in developing countries, structured…

Computation and Language · Computer Science 2019-11-27 Gokul S Krishnan , Sowmya Kamath S

A number of labeling systems based on text have been proposed to help monitor work on the United Nations (UN) Sustainable Development Goals (SDGs). Here, we present a systematic comparison of systems using a variety of text sources and show…

Computation and Language · Computer Science 2023-02-02 Dirk U. Wulff , Dominik S. Meier , Rui Mata