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Medical large language model (LLM) evaluations rely on simplified, exam-style benchmarks that rarely reflect the ambiguity of real-world medical inquiries. We introduce the CLinical Evaluation of Ambiguity and Reliability (CLEAR) framework,…

Computation and Language · Computer Science 2026-05-12 Kevin H. Guo , Chao Yan , Avinash Baidya , Katherine Brown , Xiang Gao , Juming Xiong , Zhijun Yin , Bradley A. Malin

Supervised contrastive learning (SupCon) has proven to be a powerful alternative to the standard cross-entropy loss for classification of multi-class balanced datasets. However, it struggles to learn well-conditioned representations of…

Machine Learning · Computer Science 2025-03-24 David Mildenberger , Paul Hager , Daniel Rueckert , Martin J Menten

We introduce estimation and test procedures through divergence minimiza- tion for models satisfying linear constraints with unknown parameter. These procedures extend the empirical likelihood (EL) method and share common features with…

Statistics Theory · Mathematics 2016-11-25 Michel Broniatowski , Amor Keziou

We introduce a kernel-based goodness-of-fit test for censored data, where observations may be missing in random time intervals: a common occurrence in clinical trials and industrial life-testing. The test statistic is straightforward to…

Methodology · Statistics 2018-10-11 Tamara Fernández , Arthur Gretton

There has been concern in the literature about the methodology of using secondary calibration timepoints when estimating evolutionary divergence dates. Such timepoints are divergence time estimates that have been derived from one molecular…

Populations and Evolution · Quantitative Biology 2010-01-21 David A. Morrison

The constant development of new data analysis methods in many fields of research is accompanied by an increasing awareness that these new methods often perform better in their introductory paper than in subsequent comparison studies…

Methodology · Statistics 2024-01-17 Christina Nießl , Sabine Hoffmann , Theresa Ullmann , Anne-Laure Boulesteix

In this paper, I develop a refinement of stability for matching markets with incomplete information. I introduce Information-Credible Pairwise Stability (ICPS), a solution concept in which deviating pairs can use credible, costly tests to…

Theoretical Economics · Economics 2025-10-28 Kaibalyapati Mishra

Knowledge about existence, strength, and dominant direction of causal influences is of paramount importance for understanding complex systems. With limited amounts of realistic data, however, current methods for investigating causal links…

Data Analysis, Statistics and Probability · Physics 2020-10-20 Erik Laminski , Klaus R. Pawelzik

We investigate a new setting for foreign language learning, where learners infer the meaning of unfamiliar words in a multimodal context of a sentence describing a paired image. We conduct studies with human participants using different…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yufei Wang , Adriana Kovashka , Loretta Fernández , Marc N. Coutanche , Seth Wiener

In a standard classification framework a set of trustworthy learning data are employed to build a decision rule, with the final aim of classifying unlabelled units belonging to the test set. Therefore, unreliable labelled observations,…

Applications · Statistics 2019-11-20 Andrea Cappozzo , Francesca Greselin , Thomas Brendan Murphy

Modern statisticians are often presented with hundreds or thousands of hypothesis testing problems to evaluate at the same time, generated from new scientific technologies such as microarrays, medical and satellite imaging devices, or flow…

Applications · Statistics 2008-12-18 Bradley Efron

A new method based on the rejection sampling for finding statistical tests is proposed. This method is conceptually intuitive, easy to implement, and applicable for arbitrary dimension. To illustrate its potential applicability, three…

Methodology · Statistics 2026-03-11 Markku Kuismin

Calibration refers to the estimation of unknown parameters which are present in computer experiments but not available in physical experiments. An accurate estimation of these parameters is important because it provides a scientific…

Methodology · Statistics 2019-03-21 Chih-Li Sung , Ying Hung , William Rittase , Cheng Zhu , C. F. Jeff Wu

The consideration of predictive uncertainty in medical imaging with deep learning is of utmost importance. We apply estimation of both aleatoric and epistemic uncertainty by variational Bayesian inference with Monte Carlo dropout to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-27 Max-Heinrich Laves , Sontje Ihler , Jacob F. Fast , Lüder A. Kahrs , Tobias Ortmaier

Two-sample inference for the difference of population means typically relies upon a Central Limit Theorem approximation. When data are drawn from a Negative Binomial distribution, previous work of Shilane et al. (2010) showed that a Normal…

Methodology · Statistics 2012-03-06 David Shilane , Derek Bean

Ratios of universal enumerable semimeasures corresponding to hypotheses are investigated as a solution for statistical composite hypotheses testing if an unbounded amount of computation time can be assumed. Influence testing for discrete…

Statistics Theory · Mathematics 2009-12-15 Bruno Bauwens

We consider Bayesian multiple statistical classification problem in the case where the unknown source distributions are estimated from the labeled training sequences, then the estimates are used as nominal distributions in a robust…

Information Theory · Computer Science 2021-10-11 Hüseyin Afşer

In the presence of weak overall correlation, it may be useful to investigate if the correlation is significantly and substantially more pronounced over a subpopulation. Two different testing procedures are compared. Both are based on the…

Machine Learning · Statistics 2015-04-22 Stephen Bamattre , Rex Hu , Joseph S. Verducci

This research addresses the challenge of conducting interpretable causal inference between a binary treatment and its resulting outcome when not all confounders are known. Confounders are factors that have an influence on both the treatment…

Machine Learning · Computer Science 2023-10-24 Sohaib Kiani , Jared Barton , Jon Sushinsky , Lynda Heimbach , Bo Luo

Recommender systems often suffer from selection bias as users tend to rate their preferred items. The datasets collected under such conditions exhibit entries missing not at random and thus are not randomized-controlled trials representing…

Information Retrieval · Computer Science 2024-03-05 Wonbin Kweon , Hwanjo Yu
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