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Readiness potential is a widely observed brain activity in several species including crayfish before the spontaneous behavioral initiation. However, it is poorly understood how this spontaneous activity is generated. The hypothesis that…

Neurons and Cognition · Quantitative Biology 2024-08-05 Katsushi Kagaya , Tomoyuki Kubota , Kohei Nakajima

Larval zebrafish exhibit a variety of complex undulatory swimming patterns. This repertoire is controlled by the 300 neurons projecting from brain into spinal cord. Understanding how descending control signals shape the output of spinal…

Neurons and Cognition · Quantitative Biology 2007-05-23 Scott A. Hill , Xiao-Ping Liu , Melissa A. Borla , Jorge V. Jose , Donald M. O'Malley

Animals chain movements into long-lived motor strategies, exhibiting variability across scales that reflects the interplay between internal states and environmental cues. To reveal structure in such variability, we build Markov models of…

Epileptic seizures are characterised by abnormal brain dynamics at multiple scales, engaging single neurons, neuronal ensembles and coarse brain regions. Key to understanding the cause of such emergent population dynamics, is capturing the…

Neurons and Cognition · Quantitative Biology 2022-12-13 Dominic RW Burrows

Brain activity is characterized by brain-wide spatiotemporal patterns which emerge from synapse-mediated interactions between individual neurons. Calcium imaging provides access to in vivo recordings of whole-brain activity at single-neuron…

Neurons and Cognition · Quantitative Biology 2023-09-13 Richard E. Rosch , Dominic R. W. Burrows , Christopher W. Lynn , Arian Ashourvan

Data-driven benchmarks have led to significant progress in key scientific modeling domains including weather and structural biology. Here, we introduce the Zebrafish Activity Prediction Benchmark (ZAPBench) to measure progress on the…

Jellyfish nerve nets provide insight into the origins of nervous systems, as both their taxonomic position and their evolutionary age imply that jellyfish resemble some of the earliest neuron-bearing, actively-swimming animals. Here we…

Neurons and Cognition · Quantitative Biology 2020-02-25 Fabian Pallasdies , Sven Goedeke , Wilhelm Braun , Raoul-Martin Memmesheimer

Cyborg in the brain-machine interface field has attracted more attention in recent years. To control a creature via a machine called cyborg method, three stages are considerable: stimulation of neurons, neural response, and the behavioral…

Biological Physics · Physics 2019-05-01 Mohammad Jamali , Yousef Jamali , Mehdi Golshani

Individual computations and social interactions underlying collective behavior in groups of animals are of great ethological, behavioral, and theoretical interest. While complex individual behaviors have successfully been parsed into small…

Neurons and Cognition · Quantitative Biology 2022-06-08 Roy Harpaz , Gašper Tkačik , Elad Schneidman

Progress has led to a detailed understanding of the neural mechanisms that underlie decision making in primates. However, less is known about why such mechanisms are present in the first place. Theory suggests that primate decision making…

Neurons and Cognition · Quantitative Biology 2026-01-21 Nathan J. Wispinski , Scott A. Stone , Anthony Singhal , Patrick M. Pilarski , Craig S. Chapman

Neural dynamics underlie behaviors from memory to sleep, yet identifying mechanisms for higher-order phenomena (e.g., social interaction) is experimentally challenging. Existing whole-brain models often fail to scale to single-neuron…

Neurons and Cognition · Quantitative Biology 2025-11-03 Sam Fatehmanesh Vegas , Matt Thomson , James Gornet , David Prober

Zebrafish pretectal neurons exhibit specificities for large-field optic flow patterns associated with rotatory or translatory body motion. We investigate the hypothesis that these specificities reflect the input statistics of natural optic…

Neurons and Cognition · Quantitative Biology 2018-10-10 Gerrit A. Ecke , Fabian A. Mikulasch , Sebastian A. Bruijns , Thede Witschel , Aristides B. Arrenberg , Hanspeter A. Mallot

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

Neurons and Cognition · Quantitative Biology 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

An effective evasion strategy allows prey to survive encounters with predators. Prey are generally thought to escape in a direction that is either random or serves to maximize the minimum distance from the predator. Here we introduce a…

Quantitative Methods · Quantitative Biology 2023-02-22 Yusheng Jiao , Brendan Colvert , Yi Man , Matthew J. McHenry , Eva Kanso

Larval zebrafish hunting provides a tractable setting to study how ecological and energetic constraints shape adaptive behavior in both biological brains and artificial agents. Here we develop a minimal agent-based model, training recurrent…

Neurons and Cognition · Quantitative Biology 2025-10-07 Raaghav Malik , Satpreet H. Singh , Sonja Johnson-Yu , Nathan Wu , Roy Harpaz , Florian Engert , Kanaka Rajan

Most living organisms show highly conserved physiological changes following a 24-hour cycle which goes by the name of circadian rhythm. Among experimental models, the effects of light-dark cycle have been recently investigated in the larval…

One of goals in soft robotics is to achive spontaneous behavior like real organisms. To gain a clue to achieve this, we examined the long (16-hour) spontaneous exploratory locomotion of snails. The active forager snail, Tegula nigerrima,…

Other Quantitative Biology · Quantitative Biology 2024-10-29 Katsushi Kagaya , Tomoyuki Nakano , Ryo Nakayama

Collective behaviour in living systems is observed across many scales, from bacteria to insects, to fish shoals. Zebrafish have emerged as a model system amenable to laboratory study. Here we report a three-dimensional study of the…

Statistical Mechanics · Physics 2024-05-16 Yushi Yang , Francesco Turci , Erika Kague , Chrissy L. Hammond , John Russo , C. Patrick Royall

While moving, animals must frequently make decisions about their future travel direction, whether they are alone or in a group. Here we investigate this process for zebrafish (Danio rerio), which naturally move in cohesive groups. Employing…

Biological Physics · Physics 2023-05-09 Lital Oscar , Liang Li , Dan Gorbonos , Iain D. Couzin , Nir S. Gov

During embryonic morpho-genesis, a collection of individual neurons turns into a functioning network with unique capabilities. Only recently has this most staggering example of emergent process in the natural world, began to be studied.…

Condensed Matter · Physics 2007-05-23 Ronen Segev , Eshel Ben-Jacob
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