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Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Artificial Intelligence · Computer Science 2026-01-30 Abhijith Shaji , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Greg Ver Steeg , Paul M. Thompson , Jose-Luis Ambite

In this paper, we provide an extensive overview of machine learning techniques applied to structural magnetic resonance imaging (MRI) data to obtain clinical classifiers. We specifically address practical problems commonly encountered in…

Quantitative Methods · Quantitative Biology 2018-08-20 José María Mateos-Pérez , Mahsa Dadar , María Lacalle-Aurioles , Yasser Iturria-Medina , Yashar Zeighami , Alan C. Evans

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Machine learning (ML) has advanced quickly, particularly throughout the area of health care. The diagnosis of neurodevelopment problems using ML is a very important area of healthcare. Autism spectrum disorder (ASD) is one of the…

Machine Learning · Computer Science 2024-04-04 Trapti Shrivastava , Harshal Chaudhari , Vrijendra Singh

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

Computer Vision and Pattern Recognition · Computer Science 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu

Multimodal machine learning (MML) is rapidly reshaping the way mental-health disorders are detected, characterized, and longitudinally monitored. Whereas early studies relied on isolated data streams -- such as speech, text, or wearable…

Machine Learning · Computer Science 2025-06-25 Zahraa Al Sahili , Ioannis Patras , Matthew Purver

Understanding how large language models (LLMs) represent natural language is a central challenge in natural language processing (NLP) research. Many existing methods extract word embeddings from an LLM, visualise the embedding space via…

Computation and Language · Computer Science 2026-01-12 Thomas Fabian

Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor problems for people with a detrimental effect on the functioning of the nervous system. In order to diagnose MS, multiple screening methods have been…

Machine learning (ML) has shown great promise for revolutionizing a number of areas, including healthcare. However, it is also facing a reproducibility crisis, especially in medicine. ML models that are carefully constructed from and…

Machine Learning · Computer Science 2024-09-16 Rongguang Wang , Guray Erus , Pratik Chaudhari , Christos Davatzikos

Deep learning (DL) models for disease classification or segmentation from medical images are increasingly trained using transfer learning (TL) from unrelated natural world images. However, shortcomings and utility of TL for specialized…

Machine Learning · Statistics 2021-11-11 Sambuddha Ghosal , Pratik Shah

Dementia, a prevalent neurodegenerative condition, is a major manifestation of Alzheimer's disease (AD). As the condition progresses from mild to severe, it significantly impairs the individual's ability to perform daily tasks…

Machine Learning · Computer Science 2023-11-06 Md Gulzar Hussain , Ye Shiren

Machine learning (ML) has seen enormous consideration during the most recent decade. This success started in 2012 when an ML model accomplished a remarkable triumph in the ImageNet Classification, the world's most famous competition for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-18 Imran Ul Haq

Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

Computational Engineering, Finance, and Science · Computer Science 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Transfer learning refers to machine learning techniques that focus on acquiring knowledge from related tasks to improve generalization in the tasks of interest. In MRI, transfer learning is important for developing strategies that address…

Image and Video Processing · Electrical Eng. & Systems 2021-04-05 Juan Miguel Valverde , Vandad Imani , Ali Abdollahzadeh , Riccardo De Feo , Mithilesh Prakash , Robert Ciszek , Jussi Tohka

The purpose of this study is to present and compare three denoising diffusion probabilistic models (DDPMs) that generate 3D $T_1$-weighted MRI human brain images. Three DDPMs were trained using 80,675 image volumes from 42,406 subjects…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Samuel W. Remedios , Aaron Carass , Jerry L. Prince , Blake E. Dewey

What has happened in machine learning lately, and what does it mean for the future of medical image analysis? Machine learning has witnessed a tremendous amount of attention over the last few years. The current boom started around 2009 when…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Alexander Selvikvåg Lundervold , Arvid Lundervold

As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the…

Machine Learning · Computer Science 2022-04-12 Adrienne Kline , Hanyin Wang , Yikuan Li , Saya Dennis , Meghan Hutch , Zhenxing Xu , Fei Wang , Feixiong Cheng , Yuan Luo

This article is based on the first chapter of book Chung (2013), where brain and medical images are introduced. The most widely used brain imaging modalities are magnetic resonance images (MRI), functional-MRI (fMRI) and diffusion tensor…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Moo K. Chung