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Learning individualized treatment rules (ITRs) is an important topic in precision medicine. Current literature mainly focuses on deriving ITRs from a single source population. We consider the observational data setting when the source…

Machine Learning · Statistics 2023-07-04 Rui Chen , Jared D. Huling , Guanhua Chen , Menggang Yu

Estimating treatment effects from observational data is of central interest across numerous application domains. Individual treatment effect offers the most granular measure of treatment effect on an individual level, and is the most useful…

Machine Learning · Statistics 2024-08-06 Hengrui Cai , Huaqing Jin , Lexin Li

A treatment regime is a deterministic function that dictates personalized treatment based on patients' individual prognostic information. There is a fast-growing interest in finding optimal treatment regimes to maximize expected long-term…

Statistics Theory · Mathematics 2016-11-25 Runchao Jiang , Wenbin Lu , Rui Song , Marie Davidian

Randomized trials typically estimate average relative treatment effects, but decisions on the benefit of a treatment are possibly better informed by more individualized predictions of the absolute treatment effect. In case of a binary…

Methodology · Statistics 2021-08-20 J Hoogland , J IntHout , M Belias , MM Rovers , RD Riley , FE Harrell , KGM Moons , TPA Debray , JB Reitsma

Public service programs often allocate limited resources under uncertainty about their benefits, creating a need for randomization to support credible evaluation. In practice, however, applicants commonly enter waitlists where resources are…

Machine Learning · Computer Science 2026-05-26 JungHo Lee , Johnna Sundberg , Pim Welle , Bryan Wilder

Data augmentation is one of the most effective techniques to improve the generalization performance of deep neural networks. Yet, despite often facing limited data availability in medical image analysis, it is frequently underutilized. This…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Adam Tupper , Christian Gagné

Despite dropout's ubiquity in machine learning, its effectiveness as a form of data augmentation remains under-explored. We address two key questions: (i) When is dropout effective as an augmentation strategy? (ii) Is dropout uniquely…

Machine Learning · Computer Science 2025-06-02 Rickard Brüel-Gabrielsson , Tongzhou Wang , Manel Baradad , Justin Solomon

Hypergraphs provide an effective abstraction for modeling multi-way group interactions among nodes, where each hyperedge can connect any number of nodes. Different from most existing studies which leverage statistical dependencies, we study…

Machine Learning · Computer Science 2022-07-12 Jing Ma , Mengting Wan , Longqi Yang , Jundong Li , Brent Hecht , Jaime Teevan

Estimation and evaluation of individualized treatment rules have been studied extensively, but real-world treatment resource constraints have received limited attention in existing methods. We investigate a setting in which treatment is…

Methodology · Statistics 2022-11-24 Hongxiang Qiu , Marco Carone , Alex Luedtke

The ability to predict individualized treatment effects (ITEs) based on a given patient's profile is essential for personalized medicine. We propose a hypothesis testing approach to choosing between two potential treatments for a given…

Methodology · Statistics 2020-08-11 Tianxi Cai , Tony Cai , Zijian Guo

We discuss training techniques, objectives and metrics toward personalization of deep learning models. In machine learning, personalization addresses the goal of a trained model to target a particular individual by optimizing one or more…

Machine Learning · Computer Science 2020-03-11 Johannes Schneider , Michail Vlachos

As machine learning applications grow increasingly ubiquitous and complex, they face an increasing set of requirements beyond accuracy. The prevalent approach to handle this challenge is to aggregate a weighted combination of requirement…

Machine Learning · Computer Science 2026-01-07 Aneesh Barthakur , Luiz F. O. Chamon

Uplift models support decision-making in marketing campaign planning. Estimating the causal effect of a marketing treatment, an uplift model facilitates targeting communication to responsive customers and efficient allocation of marketing…

Machine Learning · Computer Science 2019-11-21 Robin M. Gubela , Stefan Lessmann , Szymon Jaroszewicz

Selecting causal inference models for estimating individualized treatment effects (ITE) from observational data presents a unique challenge since the counterfactual outcomes are never observed. The problem is challenged further in the…

Machine Learning · Computer Science 2021-02-15 Trent Kyono , Ioana Bica , Zhaozhi Qian , Mihaela van der Schaar

In personalised decision making, evidence is required to determine whether an action (treatment) is suitable for an individual. Such evidence can be obtained by modelling treatment effect heterogeneity in subgroups. The existing…

Methodology · Statistics 2022-06-24 Jiuyong Li , Lin Liu , Shisheng Zhang , Saisai Ma , Thuc Duy Le , Jixue Liu

AUC (Area under the ROC curve) is an important performance measure for applications where the data is highly imbalanced. Learning to maximize AUC performance is thus an important research problem. Using a max-margin based surrogate loss…

Artificial Intelligence · Computer Science 2016-12-28 Vishal Kakkar , Shirish K. Shevade , S Sundararajan , Dinesh Garg

In this work we explore Unsupervised Domain Adaptation (UDA) of pretrained language models for downstream tasks. We introduce UDALM, a fine-tuning procedure, using a mixed classification and Masked Language Model loss, that can adapt to the…

Computation and Language · Computer Science 2021-04-16 Constantinos Karouzos , Georgios Paraskevopoulos , Alexandros Potamianos

F-measures are popular performance metrics, particularly for tasks with imbalanced data sets. Algorithms for learning to maximize F-measures follow two approaches: the empirical utility maximization (EUM) approach learns a classifier having…

Machine Learning · Computer Science 2012-06-22 Ye Nan , Kian Ming Chai , Wee Sun Lee , Hai Leong Chieu

Policy learning can be used to extract individualized treatment regimes from observational data in healthcare, civics, e-commerce, and beyond. One big hurdle to policy learning is a commonplace lack of overlap in the data for different…

Machine Learning · Statistics 2020-12-04 Nathan Kallus

In unsupervised combinatorial optimization (UCO), during training, one aims to have continuous decisions that are promising in a probabilistic sense for each training instance, which enables end-to-end training on initially discrete and…

Machine Learning · Computer Science 2025-06-23 Fanchen Bu , Kijung Shin
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