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Markov state models (MSMs) have been successful in computing metastable states, slow relaxation timescales and associated structural changes, and stationary or kinetic experimental observables of complex molecules from large amounts of…

Chemical Physics · Physics 2015-06-17 Frank Noe , Hao Wu , Jan-Hendrik Prinz , Nuria Plattner

Hidden Markov models with observations in a Euclidean space play an important role in signal and image processing. Previous work extending to models where observations lie in Riemannian manifolds based on the Baum-Welch algorithm suffered…

Machine Learning · Computer Science 2022-07-05 Quinten Tupker , Salem Said , Cyrus Mostajeran

People are living longer than ever before, and with this arises new complications and challenges for humanity. Among the most pressing of these challenges is of understanding the role of aging in the development of dementia. This paper is…

Methodology · Statistics 2018-08-07 Jonathan P Williams , Curtis B Storlie , Terry M Therneau , Clifford R Jack , Jan Hannig

Data representation techniques have made a substantial contribution to advancing data processing and machine learning (ML). Improving predictive power was the focus of previous representation techniques, which unfortunately perform rather…

Machine Learning · Computer Science 2022-05-24 Qiyou Duan , Hadi Ghauch , Taejoon Kim

Nature, as far as we know, evolves continuously through space and time. Yet the ubiquitous hidden Markov model (HMM)--originally developed for discrete time and space analysis in natural language processing--remains a central tool in…

Biomolecules · Quantitative Biology 2025-06-09 Max Schweiger , Ayush Saurabh , Steve Pressé

Recurrent neural networks (RNNs) provide a powerful approach in neuroscience to infer latent dynamics in neural populations and to generate hypotheses about the neural computations underlying behavior. However, past work has focused on…

Machine Learning · Computer Science 2025-10-30 Elia Torre , Michele Viscione , Lucas Pompe , Benjamin F Grewe , Valerio Mante

The hidden Markov model (HMM) is a classic modeling tool with a wide swath of applications. Its inception considered observations restricted to a finite alphabet, but it was quickly extended to multivariate continuous distributions. In this…

Methodology · Statistics 2022-05-30 Adam B Kashlak , Prachi Loliencar , Giseon Heo

Industrial processes generate a massive amount of monitoring data that can be exploited to uncover hidden time losses in the system. This can be used to enhance the accuracy of maintenance policies and increase the effectiveness of the…

Applications · Statistics 2025-08-27 Fernando Miguelez , Josu Doncel , Maria Dolores Ugarte

We propose the segmented iHMM (siHMM), a hierarchical infinite hidden Markov model (iHMM) that supports a simple, efficient inference scheme. The siHMM is well suited to segmentation problems, where the goal is to identify points at which a…

Machine Learning · Statistics 2016-02-23 Ardavan Saeedi , Matthew Hoffman , Matthew Johnson , Ryan Adams

This paper presents a mathematical framework for causal nonlinear prediction in settings where observations are generated from an underlying hidden Markov model (HMM). Both the problem formulation and the proposed solution are motivated by…

Machine Learning · Computer Science 2026-03-16 Heng-Sheng Chang , Prashant G. Mehta

Pairwise Markov Models (PMMs) extend the wellknown Hidden Markov Models (HMMs). Being significantly more general, PMMs enable several types of processing, like Bayesian filtering or smoothing, similar to those used in HMMs. In this paper,…

Dynamical Systems · Mathematics 2024-02-13 Marc Escudier , Ikram Abdelkefi , Clément Fernandes , Wojciech Pieczynski

Estimating the difficulty of input questions as perceived by large language models (LLMs) is essential for accurate performance evaluation and adaptive inference. Existing methods typically rely on repeated response sampling, auxiliary…

Computation and Language · Computer Science 2025-09-17 Yubo Zhu , Dongrui Liu , Zecheng Lin , Wei Tong , Sheng Zhong , Jing Shao

The Continuous-Time Hidden Markov Model (CT-HMM) is an attractive approach to modeling disease progression due to its ability to describe noisy observations arriving irregularly in time. However, the lack of an efficient parameter learning…

In this work, we extend the idea of Quantum Markov chains [S. Gudder. Quantum Markov chains. J. Math. Phys., 49(7), 2008] in order to propose Quantum Hidden Markov Models (QHMMs). For that, we use the notions of Transition Operation…

Quantum Physics · Physics 2017-03-03 Michał Cholewa , Piotr Gawron , Przemysław Głomb , Dariusz Kurzyk

Logical hidden Markov models (LOHMMs) upgrade traditional hidden Markov models to deal with sequences of structured symbols in the form of logical atoms, rather than flat characters. This note formally introduces LOHMMs and presents…

Artificial Intelligence · Computer Science 2011-09-13 L. De Raedt , K. Kersting , T. Raiko

In this study, we address the interpretability issue in complex, black-box Machine Learning models applied to sequence data. We introduce the Model-Based tree Hidden Semi-Markov Model (MOB-HSMM), an inherently interpretable model aimed at…

Machine Learning · Computer Science 2023-10-31 Chan Hsu , Wei-Chun Huang , Jun-Ting Wu , Chih-Yuan Li , Yihuang Kang

Visual place recognition needs to be robust against appearance variability due to natural and man-made causes. Training data collection should thus be an ongoing process to allow continuous appearance changes to be recorded. However, this…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Anh-Dzung Doan , Yasir Latif , Tat-Jun Chin , Ian Reid

This paper studies the robustness of quasi-maximum-likelihood (QML) estimation in hidden Markov models (HMMs) when the regime-switching structure is misspecified. Specifically, we examine the case where the true data-generating process…

Econometrics · Economics 2026-01-14 Demian Pouzo , Martin Sola , Zacharias Psaradakis

Lane determination and lane sequence determination are important components for many Connected and Automated Vehicle (CAV) applications. Lane determination has been solved using Hidden Markov Model (HMM) among other methods. The existing…

Robotics · Computer Science 2025-05-13 Mike Stas , Wang Hu , Jay A. Farrell

We present an efficient exact algorithm for estimating state sequences from outputs (or observations) in imprecise hidden Markov models (iHMM), where both the uncertainty linking one state to the next, and that linking a state to its…

Artificial Intelligence · Computer Science 2012-10-08 Jasper De Bock , Gert de Cooman