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Related papers: A Contrast Synthesized Thalamic Nuclei Segmentatio…

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A cascaded multi-planar scheme with a modified residual U-Net architecture was used to segment thalamic nuclei on conventional and white-matter-nulled (WMn) magnetization prepared rapid gradient echo (MPRAGE) data. A single network was…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Mohammad S Majdi , Mahesh B Keerthivasan , Brian K Rutt , Natalie M Zahr , Jeffrey J Rodriguez , Manojkumar Saranathan

The human thalamus is a highly connected subcortical grey-matter structure within the brain. It comprises dozens of nuclei with different function and connectivity, which are affected differently by disease. For this reason, there is…

Purpose: Thalamic nuclei are largely invisible in conventional MRI due to poor contrast. Thalamus Optimized Multi-Atlas Segmentation (THOMAS) provides automatic segmentation of 12 thalamic nuclei using white-matter-nulled (WMn) MPRAGE…

Image and Video Processing · Electrical Eng. & Systems 2020-06-30 Ritobrato Datta , Micky K. Bacchus , Dushyant Kumar , Mark A. Elliott , Aditya Rao , Sudipto Dolui , Ravinder Reddy , Brenda L Banwell , Manojkumar Saranathan

The thalamus is a subcortical gray matter structure that plays a key role in relaying sensory and motor signals within the brain. Its nuclei can atrophy or otherwise be affected by neurological disease and injuries including mild traumatic…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Chang Yan , Muhan Shao , Zhangxing Bian , Anqi Feng , Yuan Xue , Jiachen Zhuo , Rao P. Gullapalli , Aaron Carass , Jerry L. Prince

Thalamic alterations are relevant to many neurological disorders including Alzheimer's disease, Parkinson's disease and multiple sclerosis. Routine interventions to improve symptom severity in movement disorders, for example, often consist…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Veronica Corona , Jan Lellmann , Peter Nestor , Carola-Bibiane Schoenlieb , Julio Acosta-Cabronero

Accurate segmentation of thalamic nuclei from magnetic resonance images is important due to the distinct roles of these nuclei in overall brain function and to their differential involvement in neurological and psychiatric disorders.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Anqi Feng , Zhangxing Bian , Samuel W. Remedios , Savannah P. Hays , Blake E. Dewey , Alexa Colinco , Jiachen Zhuo , Dan Benjamini , Jerry L. Prince

Accurate segmentation of thalamic nuclei, crucial for understanding their role in healthy cognition and in pathologies, is challenging to achieve on standard T1-weighted (T1w) magnetic resonance imaging (MRI) due to poor image contrast.…

Image and Video Processing · Electrical Eng. & Systems 2023-04-17 Julie P. Vidal , Lola Danet , Patrice Péran , Jérémie Pariente , Meritxell Bach Cuadra , Natalie M. Zahr , Emmanuel J. Barbeau , Manojkumar Saranathan

The thalamus is a subcortical structure of central importance to brain function, which is organized in smaller nuclei with specialized roles. Despite significant functional and clinical relevance, locating and distinguishing the different…

Accurate segmentation of thalamic nuclei is important for better understanding brain function and improving disease treatment. Traditional segmentation methods often rely on a single T1-weighted image, which has limited contrast in the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Anqi Feng , Zhangxing Bian , Blake E. Dewey , Alexa Gail Colinco , Jiachen Zhuo , Jerry L. Prince

The thalamus consists of several histologically and functionally distinct nuclei increasingly implicated in brain pathology and important for treatment, motivating the need for development of fast and accurate thalamic segmentation. The…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Charles Iglehart , Martin Monti , Joshua Cain , Thomas Tourdias , Manojkumar Saranathan

Accurate thalamic nuclei segmentation is crucial for understanding neurological diseases, brain functions, and guiding clinical interventions. However, the optimal inputs for segmentation remain unclear. This study systematically evaluates…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Anqi Feng , Zhangxing Bian , Samuel W. Remedios , Savannah P. Hays , Blake E. Dewey , Jiachen Zhuo , Dan Benjamini , Jerry L. Prince

With the advent of convolutional neural networks~(CNN), supervised learning methods are increasingly being used for whole brain segmentation. However, a large, manually annotated training dataset of labeled brain images required to train…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Amod Jog , Andrew Hoopes , Douglas N. Greve , Koen Van Leemput , Bruce Fischl

The thalamus and its constituent nuclei are critical for a broad range of cognitive and sensorimotor processes, and implicated in many neurological and neurodegenerative conditions. However, the functional involvement and specificity of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Brendan Williams , Dan Nguyen , Julie Vidal , Alzheimer's Disease Neuroimaging Initiative , Manojkumar Saranathan

The accurate classification of mass lesions in the adrenal glands (adrenal masses), detected with computed tomography (CT), is important for diagnosis and patient management. Adrenal masses can be benign or malignant and benign masses have…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Lei Bi , Jinman Kim , Tingwei Su , Michael Fulham , David Dagan Feng , Guang Ning

This study systematically investigates the impact of image enhancement techniques on Convolutional Neural Network (CNN)-based Brain Tumor Segmentation, focusing on Histogram Equalization (HE), Contrast Limited Adaptive Histogram…

Image and Video Processing · Electrical Eng. & Systems 2024-04-09 Shoffan Saifullah , Andri Pranolo , Rafał Dreżewski

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Carotid arteries vulnerable plaques are a crucial factor in the screening of atherosclerosis by ultrasound technique. However, the plaques are contaminated by various noises such as artifact, speckle noise, and manual segmentation may be…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Yanchao Yuan , Cancheng Li , Lu Xu , Ke Zhang , Yang Hua , Jicong Zhang

Convolutional Neural Networks (CNNs) work very well for supervised learning problems when the training dataset is representative of the variations expected to be encountered at test time. In medical image segmentation, this premise is…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Neerav Karani , Ertunc Erdil , Krishna Chaitanya , Ender Konukoglu

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Zunaira Rauf , Abdul Rehman Khan , Asifullah Khan
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