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Protein interaction networks aim to summarize the complex interplay of proteins in an organism. Early studies suggested that the position of a protein in the network determines its evolutionary rate but there has been considerable…

Molecular Networks · Quantitative Biology 2007-05-23 Ino Agrafioti , Jonathan Swire , James Abbott , Derek Huntley , Sarah Butcher , Michael P. H. Stumpf

Biological evolution depends on the passing down to subsequent generations of genetic information encoding beneficial traits, and on the removal of unfit individuals by a selection mechanism. However, selection acts on phenotypes, and is…

Populations and Evolution · Quantitative Biology 2026-05-01 Bastien Mallein , Francesco Paparella , Emmanuel Schertzer , Zsófia Talyigás

Evolving systems, be it an antibody repertoire in the face of mutating pathogens or a microbial population exposed to varied antibiotics, constantly search for adaptive solutions in time-varying fitness landscapes. Generalists correspond to…

Biological Physics · Physics 2020-07-01 Shenshen Wang , Lei Dai

The number of ribosomes in a cell is considered as limiting, and gene expression is thus largely determined by their cellular concentration. In this work we develop a toy model to study the trade-off between the ribosomal supply and the…

Subcellular Processes · Quantitative Biology 2020-02-19 Pascal S. Rogalla , Timothy J. Rudge , Luca Ciandrini

We propose a model for co-evolving ecosystems that takes into account two levels of description of an organism, for instance genotype and phenotype. Performance at the macroscopic level forces mutations at the microscopic level. These, in…

adap-org · Physics 2007-05-23 Guillermo Abramson , Jose Luis Vega

Frequency-dependent selection reflects the interaction between different species as they battle for limited resources in their environment. In a stochastic evolutionary game the species relative fitnesses guides the evolutionary dynamics…

Probability · Mathematics 2020-12-29 Lea Popovic , Liam Peuckert

Prion and prion-like molecules are a type of self replicating aggregate protein that have been implicated in a variety of neurodegenerative diseases. Over recent decades the molecular dynamics of prions have been characterized both…

Populations and Evolution · Quantitative Biology 2022-07-06 Saul Acevedo , Alexander J. Stewart

Evolutionary complexity is here measured by the number of trials/evaluations needed for evolving a logical gate in a non-linear medium. Behavioural complexity of the gates evolved is characterised in terms of cellular automata behaviour. We…

Neural and Evolutionary Computing · Computer Science 2010-11-23 Andy Adamatzky , Larry Bull

This paper investigates the influence of genotype size on evolutionary algorithms' performance. We consider genotype compression (where genotype is smaller than phenotype) and expansion (genotype is larger than phenotype) and define…

Neural and Evolutionary Computing · Computer Science 2021-05-26 Lucija Planinic , Marko Djurasevic , Luca Mariot , Domagoj Jakobovic , Stjepan Picek , Carlos Coello Coello

The effect of phenotypic plasticity on evolution, the so-called Baldwin effect, has been studied extensively for more than 100 years. Plasticity is known to influence the speed of evolution towards a specific genetic configuration, but…

Populations and Evolution · Quantitative Biology 2017-12-27 Stefano Bennati , Leonel Aguilar , Dirk Helbing

The mechanisms underlying eco-evolutionary dynamics (the feedback between ecological and evolutionary processes) are often unknown. Here, we propose that classical theory from behavioral ecology can provide a greater understanding of the…

Populations and Evolution · Quantitative Biology 2019-12-23 Kiyoko M. Gotanda , Damien R. Farine , Claudius F. Kratochwil , Kate L. Laskowski , Pierre-Olivier Montiglio

It has been hypothesized that one of the main reasons evolution has been able to produce such impressive adaptations is because it has improved its own ability to evolve -- "the evolution of evolvability". Rupert Riedl, for example, an…

Populations and Evolution · Quantitative Biology 2016-12-20 Loizos Kounios , Jeff Clune , Kostas Kouvaris , Günter P. Wagner , Mihaela Pavlicev , Daniel M. Weinreich , Richard A. Watson

Information theoretic analysis of large evolved programs produced by running genetic programming for up to a million generations has shown even functions as smooth and well behaved as floating point addition and multiplication loose entropy…

Neural and Evolutionary Computing · Computer Science 2021-12-03 W. B. Langdon

This paper attempts to connects the evolution of computer languages with the evolution of life, where the later has been dictated by \emph{theory of evolution of species}, and tries to give supportive evidence that the new languages are…

Programming Languages · Computer Science 2020-07-07 K. R. Chowdhary

Constraints on changes in expression levels across all cell components imposed by the steady growth of cells have recently been discussed both experimentally and theoretically. By assuming a small environmental perturbation and considering…

Populations and Evolution · Quantitative Biology 2018-04-18 Chikara Furusawa , Kunihiko Kaneko

Neural codes appear efficient. Naturally, neuroscientists contend that an efficient process is responsible for generating efficient codes. They argue that natural selection is the efficient process that generates those codes. Although…

Neurons and Cognition · Quantitative Biology 2022-03-21 Han Kim

Dispersal is a well recognized driver of ecological and evolutionary dynamics, and simultaneously an evolving trait. Dispersal evolution has traditionally been studied in single-species metapopulations so that it remains unclear how…

We study the emergence of cell differentiation under the assumption of the existence of a given number of tradeoffs between genes encoding different functions. In the model the viability of colonies is determined by the capability of their…

Populations and Evolution · Quantitative Biology 2017-06-06 André Amado , Paulo R. A. Campos

The relationship between intelligence and evolution is bidirectional: while evolution can help evolve intelligences, the degree of intelligence itself can impact evolution (Baldwin, 1896). In the field of Evolutionary Computation, the…

Neural and Evolutionary Computing · Computer Science 2023-10-17 Lakshwin Shreesha

As input data distributions evolve, the predictive performance of machine learning models tends to deteriorate. In practice, new input data tend to come without target labels. Then, state-of-the-art techniques model input data distributions…

Machine Learning · Computer Science 2023-09-08 Carlos Mougan , Klaus Broelemann , David Masip , Gjergji Kasneci , Thanassis Thiropanis , Steffen Staab