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Much recent work has explored molecular and population-genetic constraints on the rate of protein sequence evolution. The best predictor of evolutionary rate is expression level, for reasons which have remained unexplained. Here, we…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Allan Drummond , Jesse D. Bloom , Christoph Adami , Claus O. Wilke , Frances H. Arnold

Natural selection imply that any organisms including human being will evolve to improve its fitness advantage and the selected genotype or phenotype in equilibrium state will not vary over the time. However, evolutionary process of…

Populations and Evolution · Quantitative Biology 2024-01-30 Jia-Xu Han , Rui-Wu Wang

The ability of organisms to accurately sense their environment and respond accordingly is critical for evolutionary success. However, exactly how the sensory ability influences fitness is a topic of active research, while the necessity of a…

Populations and Evolution · Quantitative Biology 2020-11-11 Alexander S. Moffett , Nigel Wallbridge , Carrol Plummer , Andrew W. Eckford

Exploiting others is beneficial individually but it could also be detrimental globally. The reverse is also true: a higher cooperation level may change the environment in a way that is beneficial for all competitors. To explore the possible…

Physics and Society · Physics 2018-02-23 Attila Szolnoki , Xiaojie Chen

In complex environments, there are costs to both ignorance and perception. An organism needs to track fitness-relevant information about its world, but the more information it tracks, the more resources it must devote to memory and…

Neurons and Cognition · Quantitative Biology 2018-10-17 Sarah E. Marzen , Simon DeDeo

Concomitant with the evolution of biological diversity must have been the evolution of mechanisms that facilitate evolution, due to the essentially infinite complexity of protein sequence space. We describe how evolvability can be an object…

Populations and Evolution · Quantitative Biology 2009-11-10 David J. Earl , Michael W. Deem

In classical evolutionary theory, genetic variation provides the source of heritable phenotypic variation on which natural selection acts. Against this classical view, several theories have emphasized that developmental variability and…

Populations and Evolution · Quantitative Biology 2011-11-08 Steven A. Frank

We are living in an uncertain and dynamically changing world, where optimal decision-making under uncertainty is directly linked to the survival of species. However, evolutionary selection pressures that shape value-based decision-making…

Populations and Evolution · Quantitative Biology 2018-04-04 Erdem Pulcu

The tempo and mode of an adaptive process is strongly determined by the structure of the fitness landscape that underlies it. In order to be able to predict evolutionary outcomes (even on the short term), we must know more about the nature…

Populations and Evolution · Quantitative Biology 2013-02-28 Bjørn Østman , Christoph Adami

Previous evolutionary studies demonstrated how evaluating evolving agents in variable environmental conditions enable them to develop solutions that are robust to environmental variation. We demonstrate how the robustness of the agents can…

Neural and Evolutionary Computing · Computer Science 2018-03-05 Nicola Milano , Jônata Tyska Carvalho , Stefano Nolfi

A fundamental question for evolutionary biology is why rates of evolution vary dramatically between proteins. Perhaps surprisingly, it is controversial how much a protein's functional importance affects its rate of evolution. In most…

Populations and Evolution · Quantitative Biology 2009-09-20 Ryan N. Gutenkunst

The adaptation rate in theoretical models of biological evolution increases with the mutation rate but only to a point when mutations into lethal states cause extinction. One would expect that removing such states should be beneficial for…

Populations and Evolution · Quantitative Biology 2024-06-27 Viktoria Blavatska , Bartlomiej Waclaw

Competition between individuals drives the evolution of whole species. Although the fittest individuals survive the longest and produce the most offspring, in some circumstances the resulting species may not be optimally fit. Here, using…

Populations and Evolution · Quantitative Biology 2015-09-24 Tim Rogers , Alan J. McKane

Populations of replicating entities frequently experience sudden or cyclical changes in environment. We explore the implications of this phenomenon via a environmental switching parameter in several common evolutionary dynamics models…

Dynamical Systems · Mathematics 2013-06-12 Marc Harper , Dashiell Fryer , Andrew Vlasic

Due to the conventional distinction between ecological (rapid) and evolutionary (slow)timescales, ecological and population models to date have typically ignored the effects of evolution. Yet the potential for rapid evolutionary change has…

Populations and Evolution · Quantitative Biology 2012-11-20 Laura E. Jones , Stephen P. Ellner

We consider evolution of a large population, where fitness of each organism is defined by many phenotypical traits. These traits result from expression of many genes. We propose a new model of gene regulation, where gene expression is…

Populations and Evolution · Quantitative Biology 2016-09-29 John Reinitz , Sergey Vakulenko , Dmitri Grigoriev , Andreas Weber

We propose an evolutionary competition model to investigate the green transition of firms, highlighting the role of adjustment costs, dynamically adjusted transition risk, and green technology progress in this process. Firms base their…

Theoretical Economics · Economics 2024-10-29 Davide Radi , Frank Westerhoff

Learning algorithms need bias to generalize and perform better than random guessing. We examine the flexibility (expressivity) of biased algorithms. An expressive algorithm can adapt to changing training data, altering its outcome based on…

Machine Learning · Statistics 2019-11-13 Julius Lauw , Dominique Macias , Akshay Trikha , Julia Vendemiatti , George D. Montanez

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

We model evolution of plants in a world, made up of different locations, with multiple environments (mutually exclusive and collectively exhaustive subsets of locations). Each environment (landmass) has temperature, rainfall, and other…

Populations and Evolution · Quantitative Biology 2019-05-27 Alexander , Khazatsky , Albert Yu , Zihao Zhao , Gabe Zuckerman
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