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The genetic code has been shown to be very error robust compared to randomly selected codes, but to be significantly less error robust than a certain code found by a heuristic algorithm. We formulate this optimisation problem as a Quadratic…

Quantitative Methods · Quantitative Biology 2015-03-13 Harry Buhrman , Peter T. S. van der Gulik , Steven M. Kelk , Wouter M. Koolen , Leen Stougie

Automated Machine Learning encompasses a set of meta-algorithms intended to design and apply machine learning techniques (e.g., model selection, hyperparameter tuning, model assessment, etc.). TPOT, a software for optimizing machine…

Machine Learning · Computer Science 2018-01-16 Unai Garciarena , Alexander Mendiburu , Roberto Santana

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

Machine Learning · Statistics 2018-09-19 Ioan Gabriel Bucur , Tom van Bussel , Tom Claassen , Tom Heskes

Dynamic gene-regulatory networks are complex since the number of potential components involved in the system is very large. Estimating dynamic networks is an important task because they compromise valuable information about interactions…

Methodology · Statistics 2012-05-15 Antonino Abbruzzo , Ernst Wit

A system-level genetic code is a hypothetical genetic code that exclusively or preferentially codes systems of interacting coadapted parts. System-level genetic codes differ from part-level genetic codes in which each discrete part is coded…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 John F. McGowan

The Folksodriven framework makes it possible for data scientists to define an ontology environment where searching for buried patterns that have some kind of predictive power to build predictive models more effectively. It accomplishes this…

Information Retrieval · Computer Science 2017-01-02 Massimiliano Dal Mas

Evolutionary robot systems are usually affected by the properties of the environment indirectly through selection. In this paper, we present and investigate a system where the environment also has a direct effect: through regulation. We…

Robotics · Computer Science 2025-06-18 Karine Miras , Eliseo Ferrante , A. E. Eiben

Retrieval-Augmented Generation (RAG) offers an effective solution to the issues faced by Large Language Models (LLMs) in hallucination generation and knowledge obsolescence by incorporating externally retrieved knowledge. However, existing…

Computation and Language · Computer Science 2025-07-01 Yongxin Xu , Ruizhe Zhang , Xinke Jiang , Yujie Feng , Yuzhen Xiao , Xinyu Ma , Runchuan Zhu , Xu Chu , Junfeng Zhao , Yasha Wang

Tangled Program Graph (TPG) is a reinforcement learning technique based on genetic programming concepts. On state-of-the-art learning environments, TPGs have been shown to offer comparable competence with Deep Neural Networks (DNNs), for a…

Neural and Evolutionary Computing · Computer Science 2020-12-16 Karol Desnos , Nicolas Sourbier , Pierre-Yves Raumer , Olivier Gesny , Maxime Pelcat

The digital transformation of automation places new demands on data acquisition and processing in industrial processes. Logical relationships between acquired data and cyclic process sequences must be correctly interpreted and evaluated. To…

Neural and Evolutionary Computing · Computer Science 2023-04-13 Marlon Löppenberg , Andreas Schwung

Finding repeated patterns or motifs in a time series is an important unsupervised task that has still a number of open issues, starting by the definition of motif. In this paper, we revise the notion of motif support, characterizing it as…

Machine Learning · Computer Science 2016-12-06 Joan Serrà , Aleksandar Matic , Josep Luis Arcos , Alexandros Karatzoglou

Evolutionary deep intelligence has recently shown great promise for producing small, powerful deep neural network models via the organic synthesis of increasingly efficient architectures over successive generations. Existing evolutionary…

Computer Vision and Pattern Recognition · Computer Science 2018-11-21 Audrey Chung , Paul Fieguth , Alexander Wong

Biological structure and function depend on complex regulatory interactions between many genes. A wealth of gene expression data is available from high-throughput genome-wide measurement technologies, but effective gene regulatory network…

Molecular Networks · Quantitative Biology 2016-03-28 Arwen Vanice Bradley , Ye Henry Li , Bokyung Choi , Wing Hung Wong

Using evolutionary computation algorithms to solve multiple tasks with knowledge sharing is a promising approach. Image feature learning can be considered as a multitask problem because different tasks may have a similar feature space.…

Computer Vision and Pattern Recognition · Computer Science 2021-07-16 Ying Bi , Bing Xue , Mengjie Zhang

This study introduces a novel method that employs tag annotation coupled with the ChatGPT language model to analyze student learning behaviors and generate personalized feedback. Central to this approach is the conversion of complex student…

Artificial Intelligence · Computer Science 2025-01-14 Yizhou Zhou , Mengqiao Zhang , Yuan-Hao Jiang , Xinyu Gao , Naijie Liu , Bo Jiang

Genetic algorithms constitute a family of black-box optimization algorithms, which take inspiration from the principles of biological evolution. While they provide a general-purpose tool for optimization, their particular instantiations can…

Neural and Evolutionary Computing · Computer Science 2023-04-11 Robert Tjarko Lange , Tom Schaul , Yutian Chen , Chris Lu , Tom Zahavy , Valentin Dalibard , Sebastian Flennerhag

The 21st century is presenting humankind with unprecedented environmental and medical challenges. The ability to design novel proteins tailored for specific purposes could transform our ability to respond timely to these issues. Recent…

Biomolecules · Quantitative Biology 2022-08-24 Noelia Ferruz , Birte Höcker

Automated industrial optimization modeling requires reliable translation of natural-language requirements into solver-executable code. However, large language models often generate non-compilable models due to missing declarations, type…

Software Engineering · Computer Science 2026-03-04 Y. Zhong , R. Huang , M. Wang , Z. Guo , YC. Li , M. Yu , Z. Jin

Grammar-Guided Genetic Programming (GGGP) employs a variety of insights from evolutionary theory to autonomously design solutions for a given task. Recent insights from evolutionary biology can lead to further improvements in GGGP…

Neural and Evolutionary Computing · Computer Science 2023-07-13 Stefano Tiso , Pedro Carvalho , Nuno Lourenço , Penousal Machado

Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene…

Quantitative Methods · Quantitative Biology 2025-05-09 Changxi Chi , Jun Xia , Jingbo Zhou , Jiabei Cheng , Chang Yu , Stan Z. Li