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Testing provides means pertaining to assuring software performance. The total aim of software industry is actually to make a certain start associated with high quality software for the end user. However, associated with software testing has…

Software Engineering · Computer Science 2016-12-30 Ahmed Mateen , Marriam Nazir , Salman Afsar Awan

Biological foundation models have shown strong performance in single-cell representation learning by applying transformer architectures directly to gene-expression matrices. However, these approaches predominantly operate in static settings…

Machine Learning · Computer Science 2026-05-28 Manuel Dileo , Andrea Sottoriva

This paper concerns applications of genetic algorithms and genetic programming to tasks for which it is difficult to find a representation that does not map to a highly complex and discontinuous fitness landscape. In such cases the standard…

Neural and Evolutionary Computing · Computer Science 2016-05-06 Michal Gregor , Juraj Spalek

Living organisms must respond to environmental changes. Generally, accurate and rapid responses are provided by simple, unidirectional networks that connect inputs with outputs. Besides accuracy and speed, biological responses should also…

Molecular Networks · Quantitative Biology 2021-09-01 Masayo Inoue , Kunihiko Kaneko

Genetic algorithms have played an important role in engineering optimization. Traditional GAs treat each gene separately. However, biophysical studies of gene regulatory networks revealed direct associations between different genes. It…

Neural and Evolutionary Computing · Computer Science 2024-05-01 Zhaoning Shi , Meng Xiang , Zhaoyang Hai , Xiabi Liu , Yan Pei

Existing genetic programming (GP) methods are typically designed based on a certain representation, such as tree-based or linear representations. These representations show various pros and cons in different domains. However, due to the…

Neural and Evolutionary Computing · Computer Science 2025-05-30 Zhixing Huang , Yi Mei , Fangfang Zhang , Mengjie Zhang , Wolfgang Banzhaf

A genetic programming (GP) variant called traceless genetic programming (TGP) is proposed in this paper. TGP is a hybrid method combining a technique for building individuals and a technique for representing individuals. The main difference…

Neural and Evolutionary Computing · Computer Science 2021-10-06 Mihai Oltean

Motivation: Gene regulatory interactions are of fundamental importance to various biological functions and processes. However, only a few previous computational studies have claimed success in revealing genome-wide regulatory landscapes…

Molecular Networks · Quantitative Biology 2017-02-09 Shupeng Gui , Rui Chen , Liang Wu , Ji Liu , Hongyu Miao

In this paper we propose new solution methods for designing tag sets for use in universal DNA arrays. First, we give integer linear programming formulations for two previous formalizations of the tag set design problem, and show that these…

Data Structures and Algorithms · Computer Science 2007-05-23 Ion I. Mandoiu , Dragos Trinca

The dynamic multi-mode resource-constrained project scheduling problem (DMRCPSP) is of practical importance, as it requires making real-time decisions under changing project states and resource availability. Genetic Programming (GP) has…

Neural and Evolutionary Computing · Computer Science 2026-03-18 Yuan Tian , Yi Mei , Mengjie Zhang

We present new techniques for synthesizing programs through sequences of mutations. Among these are (1) a method of local scoring assigning a score to each expression in a program, allowing us to more precisely identify buggy code, (2)…

Neural and Evolutionary Computing · Computer Science 2023-01-26 Max Vistrup

Genetic Regulatory Networks (GRNs) plays a vital role in the understanding of complex biological processes. Modeling GRNs is significantly important in order to reveal fundamental cellular processes, examine gene functions and understanding…

Computational Engineering, Finance, and Science · Computer Science 2012-05-10 Khalid Raza , Rafat Parveen

We present the Star-Based Automated Single-locus and Epistasis analysis tool - Genetic Programming (StarBASE-GP), an automated framework for discovering meaningful genetic variants associated with phenotypic variation in large-scale genomic…

Neural and Evolutionary Computing · Computer Science 2025-05-30 Jose Guadalupe Hernandez , Attri Ghosh , Philip J. Freda , Yufei Meng , Nicholas Matsumoto , Jason H. Moore

Grammars provide a convenient and powerful mechanism to define the space of possible solutions for a range of problems. However, when used in grammatical evolution (GE), great care must be taken in the design of a grammar to ensure that the…

Neural and Evolutionary Computing · Computer Science 2022-04-18 Grant Dick , Peter A. Whigham

Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

Biomolecules · Quantitative Biology 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

We develop a symbolic regression framework for extracting the governing mathematical expressions from observed data. The evolutionary approach, faiGP, is designed to leverage the properties of a function algebra that have been encoded into…

Neural and Evolutionary Computing · Computer Science 2022-03-18 Shahab Razavi , Eric R. Gamazon

High-quality instruction data is crucial for developing large language models (LLMs), yet existing approaches struggle to effectively control instruction complexity. We present TAG-INSTRUCT, a novel framework that enhances instruction…

Computation and Language · Computer Science 2025-06-03 He Zhu , Zhiwen Ruan , Junyou Su , Xingwei He , Yun Chen , Wenjia Zhang , Guanhua Chen

Transformer Semantic Genetic Programming (TSGP) is a semantic search approach that uses a pre-trained transformer model as a variation operator to generate offspring programs with high semantic similarity to a given parent. Unlike other…

Machine Learning · Computer Science 2026-05-01 Philipp Anthes , Dominik Sobania , Franz Rothlauf

Genetic programming (GP) is a commonly used approach to solve symbolic regression (SR) problems. Compared with the machine learning or deep learning methods that depend on the pre-defined model and the training dataset for solving SR…

Neural and Evolutionary Computing · Computer Science 2022-05-23 Baihe He , Qiang Lu , Qingyun Yang , Jake Luo , Zhiguang Wang

Personalisation in smart phones requires adaptability to dynamic context based on user mobility, application usage and sensor inputs. Current personalisation approaches, which rely on static logic that is developed a priori, do not provide…

Neural and Evolutionary Computing · Computer Science 2014-08-12 Philip Valencia , Aiden Haak , Alban Cotillon , Raja Jurdak
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