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Safety analyses in terms of adverse events (AEs) are an important aspect of benefit-risk assessments of therapies. Compared to efficacy analyses AE analyses are often rather simplistic. The probability of an AE of a specific type is…

Applications · Statistics 2021-05-20 Regina Stegherr , Claudia Schmoor , Michael Lübbert , Tim Friede , Jan Beyersmann

In topological data analysis, we want to discern topological and geometric structure of data, and to understand whether or not certain features of data are significant as opposed to simply random noise. While progress has been made on…

Computational Geometry · Computer Science 2020-01-10 So Mang Han , Taylor Okonek , Nikesh Yadav , Xiaojun Zheng

Most real-world networks are embedded in latent geometries. If a node in a network is found in the vicinity of another node in the latent geometry, the two nodes have a disproportionately high probability of being connected by a link. The…

Physics and Society · Physics 2024-06-19 Bukyoung Jhun

Topological data analysis has emerged as a powerful tool for extracting the metric, geometric and topological features underlying the data as a multi-resolution summary statistic, and has found applications in several areas where data…

Probability · Mathematics 2024-02-16 Siddharth Vishwanath , Kenji Fukumizu , Satoshi Kuriki , Bharath Sriperumbudur

We use topological data analysis (TDA) to study how data transforms as it passes through successive layers of a deep neural network (DNN). We compute the persistent homology of the activation data for each layer of the network and summarize…

Machine Learning · Computer Science 2022-05-09 Matthew Wheeler , Jose Bouza , Peter Bubenik

Time dependence is a universal phenomenon in nature, and a variety of mathematical models in terms of dynamical systems have been developed to understand the time-dependent behavior of real-world problems. Originally constructed to analyze…

Algebraic Topology · Mathematics 2018-02-14 Zixuan Cang , Elizabeth Munch , Guo-Wei Wei

We develop a topology data analysis-based method to detect early signs for critical transitions in financial data. From the time-series of multiple stock prices, we build time-dependent correlation networks, which exhibit topological…

Mathematical Finance · Quantitative Finance 2017-01-24 Marian Gidea

In crowded scenes, detection and localization of abnormal behaviors is challenging in that high-density people make object segmentation and tracking extremely difficult. We associate the optical flows of multiple frames to capture…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Xinfeng Zhang , Su Yang , Xinjian Zhang , Weishan Zhang , Jiulong Zhang

Understanding feature-outcome associations in high-dimensional data remains challenging when relationships vary across subpopulations, yet standard methods assuming global associations miss context-dependent patterns, reducing statistical…

Methodology · Statistics 2025-11-20 Pawel Gajer , Jacques Ravel

When training transformers on graph-structured data, incorporating information about the underlying topology is crucial for good performance. Topological masking, a type of relative position encoding, achieves this by upweighting or…

Time-to-event analysis often relies on prior parametric assumptions, or, if a non-parametric approach is chosen, Cox's model. This is inherently tied to the assumption of proportional hazards, with the analysis potentially invalidated if…

Methodology · Statistics 2023-03-15 Lucia Ameis , Oliver Kuß , Annika Hoyer , Kathrin Möllenhoff

In topological data analysis, persistent homology characterizes robust topological features in data and it has a summary representation, called a persistence diagram. Statistical research for persistence diagrams have been actively…

Algebraic Topology · Mathematics 2018-10-29 Genki Kusano

Topological data analysis (TDA) is a rapidly developing collection of methods for studying the shape of point cloud and other data types. One popular approach, designed to be robust to noise and outliers, is to first use a smoothing…

Methodology · Statistics 2017-12-27 Chul Moon , Noah Giansiracusa , Nicole A. Lazar

Topological data analysis (TDA) aims to extract noise-robust features from a data set by examining the number and persistence of holes in its topology. We show that a computational problem closely related to a core task in TDA --…

Quantum Physics · Physics 2024-10-29 Casper Gyurik , Alexander Schmidhuber , Robbie King , Vedran Dunjko , Ryu Hayakawa

An important problem in network analysis is predicting a node attribute using both network covariates, such as graph embedding coordinates or local subgraph counts, and conventional node covariates, such as demographic characteristics.…

Methodology · Statistics 2023-02-24 Robert Lunde , Elizaveta Levina , Ji Zhu

We use recurrent-events survival analysis techniques and methods to analyze the duration of Olympic records. The Kaplan-Meier estimator is used to perform preliminary tests and recurrent event survivor function estimators proposed by Wang &…

Applications · Statistics 2012-07-27 Elliott Hollifield , Victoria Trevino , Adam Zarn

Persistent homology is a powerful tool for characterizing the topology of a data set at various geometric scales. When applied to the description of molecular structures, persistent homology can capture the multiscale geometric features and…

Quantitative Methods · Quantitative Biology 2018-07-31 Zixuan Cang , Guo-Wei Wei

Topological features based on persistent homology capture high-order structural information so as to augment graph neural network methods. However, computing extended persistent homology summaries remains slow for large and dense graphs and…

Machine Learning · Computer Science 2022-11-16 Zuoyu Yan , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

Topology identification and inference of processes evolving over graphs arise in timely applications involving brain, transportation, financial, power, as well as social and information networks. This chapter provides an overview of graph…

Signal Processing · Electrical Eng. & Systems 2025-12-12 Gonzalo Mateos , Yanning Shen , Georgios B. Giannakis , Ananthram Swami

This study details an approach for the analysis of social media collected political data through the lens of Topological Data Analysis, with a specific focus on Persistent Homology and the political processes they represent by proposing a…

Computers and Society · Computer Science 2024-05-01 Isabela Rocha
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