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Histological analysis of tissue samples is one of the most widely used methods for disease diagnosis. After taking a sample from a patient, it goes through a lengthy and laborious preparation, which stains the tissue to visualize different…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Yair Rivenson , Hongda Wang , Zhensong Wei , Yibo Zhang , Harun Gunaydin , Aydogan Ozcan

Human-machine teaming in medical AI requires us to understand to what degree a trained clinician should weigh AI predictions. While previous work has shown the potential of AI assistance at improving clinical predictions, existing clinical…

Human-Computer Interaction · Computer Science 2024-12-03 Jim Solomon , Laleh Jalilian , Alexander Vilesov , Meryl Mathew , Tristan Grogan , Arash Bedayat , Achuta Kadambi

Timely diagnosis of Intracranial hemorrhage (ICH) on Computed Tomography (CT) scans remains a clinical priority, yet the development of robust Artificial Intelligence (AI) solutions is still hindered by fragmented public data. To close this…

Computer Vision and Pattern Recognition · Computer Science 2025-11-07 Kasra Davoodi , Mohammad Hoseyni , Javad Khoramdel , Reza Barati , Reihaneh Mortazavi , Amirhossein Nikoofard , Mahdi Aliyari-Shoorehdeli , Jaber Hatam Parikhan

Multimodal alignment of histopathology encoders with transcriptomic and genomic data has been shown to significantly improve performance in downstream diagnostic tasks. Hematological cytology is unique in that visual single-cell evaluation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Muhammed Furkan Dasdelen , Fatih Ozlugedik , Ilaria Looser , Rao Muhammad Umer , Christian Pohlkamp , Carsten Marr

Flow cytometry is a technique that measures multiple fluorescence and light scatter-associated parameters from individual cells as they flow a single file through an excitation light source. These cells are labeled with antibodies to detect…

The efficacy of AI agents in healthcare research is hindered by their reliance on static, predefined strategies. This creates a critical limitation: agents can become better tool-users but cannot learn to become better strategic planners, a…

Artificial Intelligence · Computer Science 2025-08-08 Huiya Zhao , Yinghao Zhu , Zixiang Wang , Yasha Wang , Junyi Gao , Liantao Ma

Heart diseases remain a leading cause of morbidity and mortality worldwide, necessitating accurate and trustworthy differential diagnosis. However, existing artificial intelligence-based diagnostic methods are often limited by insufficient…

Acute lymphoblastic leukemia (ALL) is a form of blood cancer that affects the white blood cells. ALL constitutes approximately 25% of pediatric cancers. Early diagnosis and treatment of ALL are crucial for improving patient outcomes. The…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Dimitris Papaioannou , Ioannis Christou , Nikos Anagnou , Aristotelis Chatziioannou

Earlier diagnosis of Leukemia can save thousands of lives annually. The prognosis of leukemia is challenging without the morphological information of White Blood Cells (WBC) and relies on the accessibility of expensive microscopes and the…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Abdul Rehman , Talha Meraj , Aiman Mahmood Minhas , Ayisha Imran , Mohsen Ali , Waqas Sultani

Biomedical imaging and RNA sequencing with single-cell resolution improves our understanding of white blood cell diseases like leukemia. By combining morphological and transcriptomic data, we can gain insights into cellular functions and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Gizem Mert , Ario Sadafi , Raheleh Salehi , Nassir Navab , Carsten Marr

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

Detecting and classifying diseases using X-ray images is one of the more challenging core tasks in the medical and research world. Due to the recent high interest in radiological images and AI, early detection of diseases in X-ray images…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Liora Mayats-Alpay

Hereditary hemolytic anemias are genetic disorders that affect the shape and density of red blood cells. Genetic tests currently used to diagnose such anemias are expensive and unavailable in the majority of clinical labs. Here, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Ario Sadafi , Lucía María Moya Sans , Asya Makhro , Leonid Livshits , Nassir Navab , Anna Bogdanova , Shadi Albarqouni , Carsten Marr

Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Saqib Nazir , Ardhendu Behera

Artificial intelligence-based analysis of lung ultrasound imaging has been demonstrated as an effective technique for rapid diagnostic decision support throughout the COVID-19 pandemic. However, such techniques can require days- or…

Presently, Covid-19 is a serious threat to the world at large. Efforts are being made to reduce disease screening times and in the development of a vaccine to resist this disease, even as thousands succumb to it everyday. We propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Hmrishav Bandyopadhyay , Shuvayan Ghosh Dastidar , Bisakh Mondal , Biplab Banerjee , Nibaran Das

Anomaly detection is an emerging approach in digital pathology for its ability to efficiently and effectively utilize data for disease diagnosis. While supervised learning approaches deliver high accuracy, they rely on extensively annotated…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Keunho Byeon , Jinsol Song , Anh Nguyen , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

Digital pathology enables automatic analysis of histopathological sections using artificial intelligence (AI). Automatic evaluation could improve diagnostic efficiency and help find associations between morphological features and clinical…

Quick and accurate medical diagnosis is crucial for the successful treatment of a disease. Using machine learning algorithms, we have built two models to predict a hematologic disease, based on laboratory blood test results. In one…

Machine Learning · Statistics 2020-06-09 Gregor Gunčar , Matjaž Kukar , Mateja Notar , Miran Brvar , Peter Černelč , Manca Notar , Marko Notar
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