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Design of experiments is a fundamental topic in applied statistics with a long history. Yet its application is often limited by the complexity and costliness of constructing experimental designs, which involve searching a high-dimensional…

Methodology · Statistics 2022-03-29 Matthew T. Pratola , C. Devon Lin , Peter F. Craigmile

The quality of a model resulting from (black-box) system identification is highly dependent on the quality of the data that is used during the identification procedure. Designing experiments for linear time-invariant systems is well…

Systems and Control · Electrical Eng. & Systems 2024-09-10 Máté Kiss , Roland Tóth , Maarten Schoukens

We propose a computational approach to constructing exact designs on finite design spaces that are optimal for multiresponse regression experiments under a combination of the standard linear and specific 'sparsity' constraints. The linear…

Methodology · Statistics 2026-02-13 Lenka Filová , Pál Somogyi , Radoslav Harman

The network inference problem arises in biological research when one needs to quantitatively choose the best protein-interaction model for explaining a phenotype. The diverse nature of the data and nonlinear dynamics pose significant…

Molecular Networks · Quantitative Biology 2025-12-22 Guy Karlebach

We propose a new method for blind system identification. Resorting to a Gaussian regression framework, we model the impulse response of the unknown linear system as a realization of a Gaussian process. The structure of the covariance matrix…

Systems and Control · Computer Science 2016-05-20 Giulio Bottegal , Riccardo S. Risuleo , Håkan Hjalmarsson

The treatment assignment mechanism in a randomized clinical trial can be optimized for statistical efficiency within a specified class of randomization mechanisms. Optimal designs of this type have been characterized in terms of the…

Methodology · Statistics 2025-09-03 Wei Zhang , Zhiwei Zhang , Aiyi Liu

Many problems arising in control require the determination of a mathematical model of the application. This has often to be performed starting from input-output data, leading to a task known as system identification in the engineering…

Machine Learning · Statistics 2023-03-01 Wenqi Cao , Gianluigi Pillonetto

We consider optimal design of infinite-dimensional Bayesian linear inverse problems governed by partial differential equations that contain secondary reducible model uncertainties, in addition to the uncertainty in the inversion parameters.…

Optimization and Control · Mathematics 2020-06-23 Alen Alexanderian , Noemi Petra , Georg Stadler , Isaac Sunseri

We develop an interpolation-based framework for noisy linear systems with unknown system matrix with bounded norm (implying bounded growth or non-increasing energy), and bounded process noise energy. The proposed approach characterizes all…

Systems and Control · Electrical Eng. & Systems 2025-11-17 Martina Vanelli , Nima Monshizadeh , Julien M. Hendrickx

In this work, we address the exact D-optimal experimental design problem by proposing an efficient algorithm that rapidly identifies the support of its continuous relaxation. Our method leverages a column generation framework to solve such…

Optimization and Control · Mathematics 2026-05-18 Selin Ahipasaoglu , Stefano Cipolla , Jacek Gondzio

Input design is an important issue for classical system identification methods but has not been investigated for the kernel-based regularization method (KRM) until very recently. In this paper, we consider in the time domain the input…

Systems and Control · Computer Science 2017-08-21 Biqiang Mu , Tianshi Chen

This paper develops a data-driven time-limited h2 model reduction method for discrete-time linear time-invariant systems. Specifically, we formulate and solve a regularized time-limited h2 model reduction problem using only noisy impulse…

Systems and Control · Electrical Eng. & Systems 2026-05-01 Hiroki Sakamoto , Kazuhiro Sato

We consider the problem of efficient statistical inference for comparing two regression curves estimated from two samples of dependent measurements. Based on a representation of the best pair of linear unbiased estimators in continuous time…

Methodology · Statistics 2016-01-29 Holger Dette , Kirsten Schorning , Maria Konstantinou

We consider the problem of discounted optimal state-feedback regulation for general unknown deterministic discrete-time systems. It is well known that open-loop instability of systems, non-quadratic cost functions and complex nonlinear…

Systems and Control · Electrical Eng. & Systems 2020-03-31 Alexandros Tanzanakis , John Lygeros

AI planning algorithms have addressed the problem of generating sequences of operators that achieve some input goal, usually assuming that the planning agent has perfect control over and information about the world. Relaxing these…

Artificial Intelligence · Computer Science 2013-02-28 Denise L. Draper , Steve Hanks , Daniel Weld

A common approach to controlling complex networks is to directly control a subset of input nodes, which then controls the remaining nodes via network interactions. While techniques have been proposed for selecting input nodes based on…

Optimization and Control · Mathematics 2014-12-15 Andrew Clark , Basel Alomair , Linda Bushnell , Radha Poovendran

Parametric prediction error methods constitute a classical approach to the identification of linear dynamic systems with excellent large-sample properties. A more recent regularized approach, inspired by machine learning and Bayesian…

Systems and Control · Computer Science 2017-10-12 Johan Wågberg , Dave Zachariah , Thomas B. Schön

We present a probabilistic modeling framework and adaptive sampling algorithm wherein unsupervised generative models are combined with black box predictive models to tackle the problem of input design. In input design, one is given one or…

Machine Learning · Computer Science 2020-02-12 David H. Brookes , Jennifer Listgarten

We consider design issues for toxicology studies when we have a continuous response and the true mean response is only known to be a member of a class of nested models. This class of non-linear models was proposed by toxicologists who were…

Statistics Theory · Mathematics 2010-11-29 Holger Dette , Andrey Pepelyshev , Piter Shpilev , Weng Kee Wong

Most linear experimental design problems assume homogeneous variance although heteroskedastic noise is present in many realistic settings. Let a learner have access to a finite set of measurement vectors $\mathcal{X}\subset \mathbb{R}^d$…

Statistics Theory · Mathematics 2024-09-19 Justin Weltz , Tanner Fiez , Alexander Volfovsky , Eric Laber , Blake Mason , Houssam Nassif , Lalit Jain
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