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Computational text phenotyping is the practice of identifying patients with certain disorders and traits from clinical notes. Rare diseases are challenging to be identified due to few cases available for machine learning and the need for…

Tumor documentation in Germany is largely done manually, requiring reading patient records and entering data into structured databases. Large language models (LLMs) could potentially enhance this process by improving efficiency and…

Computation and Language · Computer Science 2025-08-08 Stefan Lenz , Arsenij Ustjanzew , Marco Jeray , Meike Ressing , Torsten Panholzer

Annotating lidar point clouds for autonomous driving is a notoriously expensive and time-consuming task. In this work, we show that the quality of recent self-supervised lidar scan representations allows a great reduction of the annotation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Nermin Samet , Gilles Puy , Oriane Siméoni , Renaud Marlet

Imperfect labels limit the quality of predictions learned by deep neural networks. This is particularly relevant in medical image segmentation, where reference annotations are difficult to collect and vary significantly even across expert…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Eugene Vorontsov , Samuel Kadoury

Data collection from manual labeling provides domain-specific and task-aligned supervision for data-driven approaches, and a critical mass of well-annotated resources is required to achieve reasonable performance in natural language…

Computation and Language · Computer Science 2023-11-09 Zhengyuan Liu , Hai Leong Chieu , Nancy F. Chen

Radiology report annotation is essential for clinical NLP, yet manual labeling is slow and costly. We present RadAnnotate, an LLM-based framework that studies retrieval-augmented synthetic reports and confidence-based selective automation…

Computation and Language · Computer Science 2026-03-18 Saisha Pradeep Shetty , Roger Eric Goldman , Vladimir Filkov

Longitudinal information in radiology reports refers to the sequential tracking of findings across multiple examinations over time, which is crucial for monitoring disease progression and guiding clinical decisions. Many recent automated…

Computation and Language · Computer Science 2026-01-26 Xinyi Wang , Grazziela Figueredo , Ruizhe Li , Xin Chen

Training neural networks using limited annotations is an important problem in the medical domain. Deep Neural Networks (DNNs) typically require large, annotated datasets to achieve acceptable performance which, in the medical domain, are…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Bethany H. Thompson , Gaetano Di Caterina , Jeremy P. Voisey

A major limitation in applying deep learning to artificial intelligence (AI) systems is the scarcity of high-quality curated datasets. We investigate strong augmentation based self-supervised learning (SSL) techniques to address this…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 John D. Miller , Vignesh A. Arasu , Albert X. Pu , Laurie R. Margolies , Weiva Sieh , Li Shen

The accurate extraction of clinical information from electronic medical records is particularly critical to clinical research but require much trained expertise and manual labor. In this study we developed a robust system for automated…

The exploration of cellular heterogeneity within the tumor microenvironment (TME) via single-cell RNA sequencing (scRNA-seq) is essential for understanding cancer progression and response to therapy. Current scRNA-seq approaches, however,…

Genomics · Quantitative Biology 2025-02-06 Yu-An Huang , Yue-Chao Li , Hai-Ru You , Jie Pan , Xiyue Cao , Xinyuan Li , Zhi-An Huang , Zhu-Hong You

There is a common belief that the successful training of deep neural networks requires many annotated training samples, which are often expensive and difficult to obtain especially in the biomedical imaging field. While it is often easy for…

Computer Vision and Pattern Recognition · Computer Science 2019-12-11 Tony C. W Mok , Albert C. S Chung

Real-world domain experts (e.g., doctors) rarely annotate only a decision label in their day-to-day workflow without providing explanations. Yet, existing low-resource learning techniques, such as Active Learning (AL), that aim to support…

Computation and Language · Computer Science 2023-10-24 Bingsheng Yao , Ishan Jindal , Lucian Popa , Yannis Katsis , Sayan Ghosh , Lihong He , Yuxuan Lu , Shashank Srivastava , Yunyao Li , James Hendler , Dakuo Wang

Accurate brain tumor segmentation from MRI is limited by expensive annotations and data heterogeneity across scanners and sites. We propose a semi-supervised teacher-student framework that combines an uncertainty-aware pseudo-labeling…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Jiaming Liu , Cheng Ding , Daoqiang Zhang

Objective. Annotation is expensive but essential for clinical note review and clinical natural language processing (cNLP). However, the extent to which computer-generated pre-annotation is beneficial to human annotation is still an open…

Computational pathology methods have the potential to improve access to precision medicine, as well as the reproducibility and accuracy of pathological diagnoses. Particularly the analysis of whole-slide-images (WSIs) of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Philippe Weitz , Viktoria Sartor , Balazs Acs , Stephanie Robertson , Daniel Budelmann , Johan Hartman , Mattias Rantalainen

Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

Clinical Text Notes (CTNs) contain physicians' reasoning process, written in an unstructured free text format, as they examine and interview patients. In recent years, several studies have been published that provide evidence for the…

Computation and Language · Computer Science 2022-08-19 Hlynur D. Hlynsson , Steindór Ellertsson , Jón F. Daðason , Emil L. Sigurdsson , Hrafn Loftsson

It is desirable to coarsely classify short scientific texts, such as grant or publication abstracts, for strategic insight or research portfolio management. These texts efficiently transmit dense information to experts possessing a rich…

Artificial Intelligence · Computer Science 2024-07-09 Harsh Sakhrani , Naseela Pervez , Anirudh Ravi Kumar , Fred Morstatter , Alexandra Graddy Reed , Andrea Belz

Response evaluation criteria in solid tumors (RECIST) is the standard measurement for tumor extent to evaluate treatment responses in cancer patients. As such, RECIST annotations must be accurate. However, RECIST annotations manually…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Youbao Tang , Adam P. Harrison , Mohammadhadi Bagheri , Jing Xiao , Ronald M. Summers