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In this paper, we propose a flexible cure rate model with frailty term in latent risk, which is obtained by incorporating a frailty term in risk function of latent competing causes. The number of competing causes of the event of interest…

We propose a copula based method to handle missing values in multivariate data of mixed types in multilevel data sets. Building upon the extended rank likelihood of \cite{hoff2007extending} and the multinomial probit model, our model is a…

Methodology · Statistics 2017-02-28 Jiali Wang , Bronwyn Loong , Anton H. Westveld , Alan H. Welsh

Recent advances in medical research have improved survival outcomes for patients with life-threatening diseases. As a result, the existence of long-term survivors from these illnesses is becoming common. However, conventional models in…

Applications · Statistics 2025-07-16 Dionisio Silva Neto , Francisco Louzada Neto , Vera Lucia Tomazella

Multivariate datasets are common in various real-world applications. Recently, copulas have received significant attention for modeling dependencies among random variables. A copula-based information measure is required to quantify the…

Methodology · Statistics 2024-08-06 Mohd. Arshad , Swaroop Georgy Zachariah , Ashok Kumar Pathak

In this article, we particularly address the problem of assessing the impact of clinical stage and age on the specific survival times of men with breast cancer when cure is a possibility, where there is also the interest of explaining this…

Methodology · Statistics 2021-05-11 Agatha Rodrigues , Patrick Borges , Bruno Santos

Parametric copula families have been known to flexibly capture various dependence patterns, e.g., either positive or negative dependence in either the lower or upper tails of bivariate distributions. In this paper, our objective is to…

Methodology · Statistics 2025-02-11 Ruyi Pan , Luis E. Nieto-Barajas , Radu Craiu

Although the independent censoring assumption is commonly used in survival analysis, it can be violated when the censoring time is related to the survival time, which often happens in many practical applications. To address this issue, we…

Methodology · Statistics 2024-08-28 Huazhen Yu , Lixin Zhang

Copula mixed models for trivariate (or bivariate) meta-analysis of diagnostic test accuracy studies accounting (or not) for disease prevalence have been proposed in the biostatistics literature to synthesize information. However, many…

Methodology · Statistics 2018-07-12 Aristidis K. Nikoloulopoulos

The Gaussian copula is a powerful tool that has been widely used to model spatial and/or temporal correlated data with arbitrary marginal distributions. However, this kind of model can potentially be too restrictive since it expresses a…

Methodology · Statistics 2023-05-30 Moreno Bevilacqua , Eloy Alvarado , Christian Caamaño-Carrillo

Copulas, generalized estimating equations, and generalized linear mixed models promote the analysis of grouped data where non-normal responses are correlated. Unfortunately, parameter estimation remains challenging in these three…

Methodology · Statistics 2024-10-16 Sarah S. Ji , Benjamin B. Chu , Hua Zhou , Kenneth Lange

This paper introduces a cure rate survival model by assuming that the time to the event of interest follows a beta prime distribution and that the number of competing causes of the event of interest follows a negative binomial distribution.…

Methodology · Statistics 2018-12-20 Jeremias Leão , Marcelo Bourguignon , Manoel Santos-Neto , Helton Saulo

This paper proposes new estimators for the propensity score that aim to maximize the covariate distribution balance among different treatment groups. Heuristically, our proposed procedure attempts to estimate a propensity score model by…

Econometrics · Economics 2020-04-07 Pedro H. C. Sant'Anna , Xiaojun Song , Qi Xu

A semiparametric copula-based two-part quantile regression framework is developed for the analysis of semicontinuous outcomes characterized by a point mass at zero and a continuous positive component. The proposed approach models the…

Methodology · Statistics 2026-03-17 Guanjie Lyu , Mohamed Belalia , Abdulkadir Hussein

Copula-based methods provide a flexible approach to build missing data imputation models of multivariate data of mixed types. However, the choice of copula function is an open question. We consider a Bayesian nonparametric approach by using…

Methodology · Statistics 2019-10-15 Jiali Wang , Anton Westveld , Bronwyn Loong , Alan Welsh

We present a joint copula-based model for insurance claims and sizes. It uses bivariate copulae to accommodate for the dependence between these quantities. We derive the general distribution of the policy loss without the restrictive…

Statistics Theory · Mathematics 2012-09-25 Nicole Kraemer , Eike C. Brechmann , Daniel Silvestrini , Claudia Czado

Analysis of lifetime data from epidemiological studies or destructive testing often involves current status censoring, wherein individuals are examined only once and their event status is recorded only at that specific time point. In…

Methodology · Statistics 2024-10-15 Pavithra Hariharan , P. G. Sankaran

Cure models have been developed as an alternative modelling approach to conventional survival analysis in order to account for the presence of cured subjects that will never experience the event of interest. Mixture cure models, which model…

Methodology · Statistics 2022-07-19 Eni Musta , Valentin Patilea , Ingrid Van Keilegom

This research integrates deep learning, copula functions, and survival analysis to effectively handle highly correlated and right-censored multivariate survival data. It introduces copula-based activation functions (Clayton, Gumbel, and…

Machine Learning · Statistics 2025-07-22 Jong-Min Kim , Il Do Ha , Sangjin Kim

A bivariate copula mixed model has been recently proposed to synthesize diagnostic test accuracy studies and it has been shown that is superior to the standard generalized linear mixed model (GLMM) in this context. Here we call trivariate…

Methodology · Statistics 2017-11-09 Aristidis K. Nikoloulopoulos

Joint modelling of longitudinal and time-to-event data is usually described by a joint model which uses shared or correlated latent effects to capture associations between the two processes. Under this framework, the joint distribution of…

Methodology · Statistics 2022-03-07 Zili Zhang , Christiana Charalambous , Peter Foster