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On average the lack of biological markers causes a one year diagnostic delay to detect amyotrophic lateral sclerosis (ALS). To improve the diagnostic process an automatic voice assessment based on acoustic analysis can be used. The purpose…

Sound · Computer Science 2020-03-25 Maxim Vashkevich , Alexander Petrovsky , Yuliya Rushkevich

The analysis of speech measures in individuals with amyotrophic lateral sclerosis (ALS) can provide essential information for early diagnosis and tracking disease progression. However, current methods for extracting speech and pause…

Sound · Computer Science 2022-08-24 Saeid Alavi Naeini , Leif Simmatis , Yana Yunusova , Babak Taati

Automatic prediction of amyotrophic lateral sclerosis (ALS) disease progression provides a more efficient and objective alternative than manual approaches. We propose ALS longitudinal speech transformer (ALST), a neural network-based…

We propose a cloud-based multimodal dialog platform for the remote assessment and monitoring of Amyotrophic Lateral Sclerosis (ALS) at scale. This paper presents our vision, technology setup, and an initial investigation of the efficacy of…

The analysis of speech in individuals with amyotrophic lateral sclerosis is a powerful tool to support clinicians in the assessment of bulbar dysfunction. However, current methods used in clinical practice consist of subjective evaluations…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-28 Francesco Pierotti , Andrea Bandini

Recent advances in Artificial Intelligence (AI) and the exploration of noninvasive, objective biomarkers, such as speech signals, have encouraged the development of algorithms to support the early diagnosis of neurodegenerative diseases,…

Diagnosing autism spectrum disorder (ASD) by identifying abnormal speech patterns from examiner-patient dialogues presents significant challenges due to the subtle and diverse manifestations of speech-related symptoms in affected…

Sound · Computer Science 2024-05-09 Chuanbo Hu , Jacob Thrasher , Wenqi Li , Mindi Ruan , Xiangxu Yu , Lynn K Paul , Shuo Wang , Xin Li

In this study, the development of an automatic algorithm is presented to classify the nocturnal audio recording of an obstructive sleep apnoea (OSA) patient as OSA related snore, simple snore and other sounds. Recent studies has been shown…

Audio and Speech Processing · Electrical Eng. & Systems 2021-03-03 Arun Sebastian , Peter A. Cistulli , Gary Cohen , Philip de Chazal

Amyotrophic Lateral Sclerosis (ALS) constitutes a progressive neurodegenerative disease with varying symptoms, including decline in speech intelligibility. Existing studies, which recognize dysarthria in ALS patients by predicting the…

Machine Learning · Computer Science 2025-03-05 Loukas Ilias , Dimitris Askounis

Autism Spectrum Disorders (ASD) describe a heterogeneous set of conditions classified as neurodevelopmental disorders. Although the mechanisms underlying ASD are not yet fully understood, more recent literature focused on multiple genetics…

Signal Processing · Electrical Eng. & Systems 2025-01-31 Jessica Vacca , Natascia Brondino , Fabio Dell'Acqua , Anna Vizziello , Pietro Savazzi

Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…

Computation and Language · Computer Science 2020-11-21 Mireia Farrús , Joan Codina-Filbà

Lipreading or visually recognizing speech from the mouth movements of a speaker is a challenging and mentally taxing task. Unfortunately, multiple medical conditions force people to depend on this skill in their day-to-day lives for…

Computer Vision and Pattern Recognition · Computer Science 2021-11-04 Bipasha Sen , Aditya Agarwal , Rudrabha Mukhopadhyay , Vinay Namboodiri , C V Jawahar

Autistic Spectrum Disorder (ASD) is a neurological disease characterized by difficulties with social interaction, communication, and repetitive activities. While its primary origin lies in genetics, early detection is crucial, and…

Machine Learning · Computer Science 2023-12-29 Rownak Ara Rasul , Promy Saha , Diponkor Bala , S M Rakib Ul Karim , Md. Ibrahim Abdullah , Bishwajit Saha

Amyotrophic lateral sclerosis (ALS) is a severe disease with a typical survival of 3-5 years after symptom onset. Current treatments offer only limited life extension, and the variability in patient responses highlights the need for…

Machine Learning · Computer Science 2025-11-05 Guillaume Tejedor , Veronika Peralta , Nicolas Labroche , Patrick Marcel , Hélène Blasco , Hugo Alarcan

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

The potential of deep learning in clinical speech processing is immense, yet the hurdles of limited and imbalanced clinical data samples loom large. This article addresses these challenges by showcasing the utilization of automatic speech…

Researches have shown accent classification can be improved by integrating semantic information into pure acoustic approach. In this work, we combine phonetic knowledge, such as vowels, with enhanced acoustic features to build an improved…

Sound · Computer Science 2016-02-25 Zhenhao Ge

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by a rapid motor decline, leading to respiratory failure and subsequently to death. In this context, researchers have sought for models to automatically…

Machine Learning · Computer Science 2019-07-31 Telma Pereira , Sofia Pires , Marta Gromicho , Susana Pinto , Mamede de Carvalho , Sara C. Madeira

Amyotrophic lateral sclerosis (ALS) is a degenerative disorder of the motor neurons that causes progressive paralysis in patients. Current treatment options aim to prolong survival and improve quality of life. However, due to the…

Quantitative Methods · Quantitative Biology 2025-11-20 Christian Marius Lillelund , Sanjay Kalra , Russell Greiner

Automated detection of voice disorders with computational methods is a recent research area in the medical domain since it requires a rigorous endoscopy for the accurate diagnosis. Efficient screening methods are required for the diagnosis…

Quantitative Methods · Quantitative Biology 2018-12-06 Vibhuti Gupta
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