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Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

Neurons and Cognition · Quantitative Biology 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Objective: The detection of epileptic seizures from scalp electroencephalogram (EEG) signals can facilitate early diagnosis and treatment. Previous studies suggested that the Gaussianity of EEG distributions changes depending on the…

Signal Processing · Electrical Eng. & Systems 2021-03-03 Akira Furui , Ryota Onishi , Akihito Takeuchi , Tomoyuki Akiyama , Toshio Tsuji

Objectives: This study examines human Photoplethysmogram (PPG) along with Electrocardiogram (ECG) signals to study cardiac autonomic imbalance in epileptic seizures. The significance and the prevalence of changes in PPG morphological…

Signal Processing · Electrical Eng. & Systems 2019-12-12 Seyede Mahya Safavi , Ninaz Valisharifabad , Robert Sabino , Hsinchung Chen , Ali HeydariGorji , Demi Tran , Jack Lin , Beth Lopour , Pai H. Chou

Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understanding, or even predicting, this neuromodulatory effect is…

Neurons and Cognition · Quantitative Biology 2021-06-29 Christoforos Papasavvas , Peter Neal Taylor , Yujiang Wang

Spontaneous fluctuations of the BOLD (Blood Oxygen Level-Dependent) signal, measured with fMRI (functional Magnetic Resonance Imaging), display a rich and neurobiologically relevant functional connectivity structure. This structure is…

Neurons and Cognition · Quantitative Biology 2012-09-24 Enzo Tagliazucchi , Frederic von Wegner , Astrid Morzelewski , Verena Brodbeck , Helmut Laufs

We assess electrical brain dynamics before, during, and after one-hundred human epileptic seizures with different anatomical onset locations by statistical and spectral properties of functionally defined networks. We observe a concave-like…

Neurons and Cognition · Quantitative Biology 2013-11-25 Kaspar A. Schindler , Stephan Bialonski , Marie-Therese Horstmann , Christian E. Elger , Klaus Lehnertz

Electroencephalogram (EEG) is a common tool used to understand brain activities. The data are typically obtained by placing electrodes at the surface of the scalp and recording the oscillations of currents passing through the electrodes.…

Signal Processing · Electrical Eng. & Systems 2021-02-19 Eddy Kwessi , Lloyd Edwards

Recent studies have shown that seizures can spread and terminate across brain areas via a rich diversity of spatiotemporal patterns. In particular, while the location of the seizure onset area is usually in-variant across seizures in a same…

Neurons and Cognition · Quantitative Biology 2018-05-09 Timothée Proix , Viktor K. Jirsa , Fabrice Bartolomei , Maxime Guye , Wilson Truccolo

In many realistic networks, the edges representing the interactions between the nodes are time-varying. There is growing evidence that the complex network that models the dynamics of the human brain has time-varying interconnections, i.e.,…

Neurons and Cognition · Quantitative Biology 2016-11-29 G Manjunath

The scaling behaviors of the human electroencephalogram (EEG) time series are studied using detrended fluctuation analysis. Two scaling regions are found in nearly every channel for all subjects examined. The scatter plot of the scaling…

Medical Physics · Physics 2013-05-29 Rudolph C. Hwa , Thomas C. Ferree

Repeated epileptic seizures impair around 65 million people worldwide and a successful prediction of seizures could significantly help patients suffering from refractory epilepsy. For two dogs with yearlong intracranial…

Neurons and Cognition · Quantitative Biology 2022-01-13 Hongliu Yang , Matthias Eberlein , Jens Müller , Ronald Tetzlaff

Epilepsy is typically diagnosed through electroencephalography (EEG) and long-term video-EEG (vEEG) monitoring. The manual analysis of vEEG recordings is time-consuming, necessitating automated tools for seizure detection. Recent…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Valerii A. Zuev , Elena G. Salmagambetova , Stepan N. Djakov , Lev V. Utkin

Since the manual detection of electrographic seizures in continuous electroencephalogram (EEG) monitoring is very time-consuming and requires a trained expert, attempts to develop automatic seizure detection are diverse and ongoing. Machine…

Signal Processing · Electrical Eng. & Systems 2019-08-02 Poomipat Boonyakitanont , Apiwat Lek-uthai , Krisnachai Chomtho , Jitkomut Songsiri

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

Neurons and Cognition · Quantitative Biology 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

Epilepsy is one of the most common neurological diseases, characterized by transient and unprovoked events called epileptic seizures. Electroencephalogram (EEG) is an auxiliary method used to perform both the diagnosis and the monitoring of…

Medically uncontrolled epileptic seizures affect nearly 15 million people worldwide, resulting in enormous economic and psychological burdens. Treatment of medically refractory epilepsy is essential for patients to achieve remission,…

Quantitative Methods · Quantitative Biology 2025-12-25 Yaoyue Wang , Arian Ashourvan , Guilherme Ramos , Paul Bogdan , Emily Pereira

Epileptic seizures are neurological disorders characterized by abnormal and excessive electrical activity in the brain, resulting in recurrent seizure events. Electroencephalogram (EEG) signals are widely used for seizure diagnosis due to…

Machine Learning · Computer Science 2026-04-02 Ferdaus Anam Jibon , Fazlul Hasan Siddiqui , F. Deeba , Gahangir Hossain

Inferring strength and direction of interactions from electroencephalographic (EEG) recordings is of crucial importance to improve our understanding of dynamical interdependencies underlying various physiologic and pathophysiologic…

Neurons and Cognition · Quantitative Biology 2016-10-07 Klaus Lehnertz , Henning Dickten

Interictal spikes and sharp waves in human EEG are characteristic signatures of epilepsy. These potentials originate as a result of synchronous, pathological discharge of many neurons. The reliable detection of such potentials has been the…

Biological Physics · Physics 2009-11-10 Miroslaw Latka , Ziemowit Was , Andrzej Kozik , Bruce J. West

Epileptic seizures are one of the most well-known dysfunctions of the nervous system. During a seizure, a highly synchronized behavior of neural activity is observed that can cause symptoms ranging from mild sensual malfunctions to the…

Neurons and Cognition · Quantitative Biology 2011-08-01 Christian Kuehn , Christian Meisel