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Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…

Image and Video Processing · Electrical Eng. & Systems 2019-06-25 Chenyu You , Guang Li , Yi Zhang , Xiaoliu Zhang , Hongming Shan , Shenghong Ju , Zhen Zhao , Zhuiyang Zhang , Wenxiang Cong , Michael W. Vannier , Punam K. Saha , Ge Wang

We study the effect of incorporating self-supervised denoising as a pre-processing step for training deep learning (DL) based reconstruction methods on data corrupted by Gaussian noise. K-space data employed for training are typically…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Asad Aali , Marius Arvinte , Sidharth Kumar , Yamin I. Arefeen , Jonathan I. Tamir

Diffuse Optical Tomography (DOT) is an emerging technology in medical imaging which employs light in the NIR spectrum to estimate the distribution of optical coefficients in biological tissues for diagnostic and monitoring purposes. DOT…

Numerical Analysis · Mathematics 2022-05-27 Alessandro Benfenati , Giuseppe Bisazza , Paola Causin

Limited data and low dose constraints are common problems in a variety of tomographic reconstruction paradigms which lead to noisy and incomplete data. Over the past few years sinogram denoising has become an essential pre-processing step…

Computer Vision and Pattern Recognition · Computer Science 2016-03-15 Faisal Mahmood , Nauman Shahid , Pierre Vandergheynst , Ulf Skoglund

Filtered back projection (FBP) is the most widely used method for image reconstruction in X-ray computed tomography (CT) scanners. The presence of hyper-dense materials in a scene, such as metals, can strongly attenuate X-rays, producing…

Computer Vision and Pattern Recognition · Computer Science 2019-08-02 Muhammad Usman Ghani , W. Clem Karl

Recently, deep learning(DL) methods have been proposed for the low-dose computed tomography(LdCT) enhancement, and obtain good trade-off between computational efficiency and image quality. Most of them need large number of pre-collected…

Computer Vision and Pattern Recognition · Computer Science 2018-08-09 Mingrui Geng , Yun Deng , Qian Zhao , Qi Xie , Dong Zeng , Dong Zeng , Wangmeng Zuo , Deyu Meng

Filtered back projection (FBP) is a classical method for image reconstruction from sinogram CT data. FBP is computationally efficient but produces lower quality reconstructions than more sophisticated iterative methods, particularly when…

Image and Video Processing · Electrical Eng. & Systems 2018-07-09 Dong Hye Ye , Gregery T. Buzzard , Max Ruby , Charles A. Bouman

Restoring high-quality CT images from low dose CT counterparts is an ill-posed, nonlinear problem to which Deep Learning approaches have been giving superior solutions compared to classical model-based approaches. In this article, a…

Image and Video Processing · Electrical Eng. & Systems 2019-10-16 Shabab Bazrafkan , Vincent Van Nieuwenhove , Jan Sijbers

Spectral computed tomography (CT) with photon-counting detectors holds immense potential for material discrimination and tissue characterization. However, under ultra-low-dose conditions, the sharply degraded signal-to-noise ratio (SNR) in…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Peng Peng , Xinrui Zhang , Junlin Wang , Lei Li , Shaoyu Wang , Qiegen Liu

With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhilin Guan , Wei Zhang

Low-dose CT has been a key diagnostic imaging modality to reduce the potential risk of radiation overdose to patient health. Despite recent advances, CNN-based approaches typically apply filters in a spatially invariant way and adopt…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Lu Xu , Yuwei Zhang , Ying Liu , Daoye Wang , Mu Zhou , Jimmy Ren , Jingwei Wei , Zhaoxiang Ye

Recently, Self-supervised learning methods able to perform image denoising without ground truth labels have been proposed. These methods create low-quality images by adding random or Gaussian noise to images and then train a model for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Dongkyu Won , Euijin Jung , Sion An , Philip Chikontwe , Sang Hyun Park

Computed tomography (CT) uses X-ray measurements taken from sensors around the body to generate tomographic images of the human body. Conventional reconstruction algorithms can be used if the X-ray data are adequately sampled and of high…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Ruiwen Xing , Thomas Humphries , Dong Si

Portable, low-field Magnetic Resonance Imaging (MRI) scanners are increasingly being deployed in clinical settings. However, key barriers to their widespread use include low signal-to-noise ratio (SNR), generally low image quality, and long…

High radiation dose in CT scans increases a lifetime risk of cancer and has become a major clinical concern. Recently, iterative reconstruction algorithms with Total Variation (TV) regularization have been developed to reconstruct CT images…

Medical Physics · Physics 2015-05-19 Zhen Tian , Xun Jia , Kehong Yuan , Tinsu Pan , Steve B. Jiang

Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

A major challenge in computed tomography (CT) is to reduce X-ray dose to a low or even ultra-low level while maintaining the high quality of reconstructed images. We propose a new method for CT reconstruction that combines penalized…

Machine Learning · Statistics 2017-07-11 Xuehang Zheng , Zening Lu , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

In the practical applications of computed tomography imaging, the projection data may be acquired within a limited-angle range and corrupted by noises due to the limitation of scanning conditions. The noisy incomplete projection data…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Qifeng Gao , Rui Ding , Linyuan Wang , Bin Xue , Yuping Duan

Image denoising techniques are essential to reducing noise levels and enhancing diagnosis reliability in low-dose computed tomography (CT). Machine learning based denoising methods have shown great potential in removing the complex and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Dufan Wu , Kyungsang Kim , Georges El Fakhri , Quanzheng Li

Recent years have witnessed growing interest in machine learning-based models and techniques for low-dose X-ray CT (LDCT) imaging tasks. The methods can typically be categorized into supervised learning methods and unsupervised or…

Machine Learning · Computer Science 2019-10-29 Zhipeng Li , Siqi Ye , Yong Long , Saiprasad Ravishankar
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