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In recent years, magnetic particle spectroscopy (MPS) has become a highly sensitive and versatile sensing technique for quantitative bioassays. It relies on the dynamic magnetic responses of magnetic nanoparticles (MNPs) for the detection…
Visualization of the in vivo spatial distribution of superparamagnetic iron oxide nanoparticles (SPIONs) is crucial to biomedicine. Magnetic particle imaging (MPI) is one of the most promising approaches for direct measurements of the SPION…
Since the initial patent in 2001, the Magnetic Particle Imaging (MPI) community has been striving to develop an MPI scanner suitable for human applications. Numerous contributions from different research fields, regarding tracer…
Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…
Improving resolution and sensitivity will widen possible medical applications of magnetic particle imaging. Pulsed excitation promises such benefits, at the cost of more complex hardware solutions and restrictions on drive field amplitude…
Transcranial magnetic stimulation (TMS) is widely used for understanding brain function in neurologically intact subjects and for the treatment of various disorders. However, the precise neurophysiological effects of TMS at the site of…
Magnetic stimulation is a standard tool in brain research and many fields of neurology, as well as psychiatry. From a physical perspective, one key aspect of this method is the inefficiency of available setups. Whereas the spatial field…
Compressed sensing has shown great potential in reducing data acquisition time in magnetic resonance imaging (MRI). Recently, a spread spectrum compressed sensing MRI method modulates an image with a quadratic phase. It performs better than…
The flicker-noise spectroscopy (FNS) approach is used to determine the dynamic characteristics of neuromagnetic responses by analyzing the magnetoencephalographic (MEG) signals recorded as the response of a group of control human subjects…
Nuclear Magnetic Resonance (NMR) is an intriguing quantum-mechanical effect that is used for daily life medical diagnostics and chemical analysis alike. Numerous advancements have contributed to the success of the technique, including…
Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…
The objective of this study was to characterize hemodynamic changes during trans-vascular stimulation of the renal nerve and their dependence on stimulation parameters. We employed a stimulation catheter inserted in the right renal artery…
High density neurostimulation systems are coming to market to help spinal cord injury patients by stimulating and recording neuromuscular function. However, the parameter space that these systems have to explore is exceedingly large, and…
Bearing in mind the application to core-collapse supernovae, we study nonlinear properties of the magneto-rotational instability (MRI) by means of three- dimensional simulations in the framework of a local shearing box approximation. By…
Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…
Objective: Closed-loop deep brain stimulation (DBS) may improve current clinical DBS treatment for neurological movement disorders, but control algorithms may perform differently across patients. New metrics are needed for comparing and…
We investigate the stimulus-dependent tuning properties of a noisy ionic conductance model for intrinsic subthreshold oscillations in membrane potential and associated spike generation. On depolarization by an applied current, the model…
Magnetic nanoparticles (MNPs) have been extensively used as contrasts and tracers for bioimaging, heating sources for tumor therapy, carriers for controlled drug delivery, and labels for magnetic immunoassays. Here, we describe a MNP…
In terms of the long-distance communication of a single neuron, interpulse intervals (IPIs) are a possible alternative to rate and binary codes. As a proxy for IPI, the time-to-spike (TTS) for a neuron can be found in the biophysical and…
Electrical stimulation of residual nerves can be used to provide amputees with intuitive sensory feedback. An important aspect of this artificial sensory feedback is the ability to convey the magnitude of tactile stimuli. Using classical…