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Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

Most of the modern instance segmentation approaches fall into two categories: region-based approaches in which object bounding boxes are detected first and later used in cropping and segmenting instances; and keypoint-based approaches in…

Computer Vision and Pattern Recognition · Computer Science 2020-03-17 Xingqian Xu , Mang Tik Chiu , Thomas S. Huang , Honghui Shi

Instance segmentation in 3D images is a fundamental task in biomedical image analysis. While deep learning models often work well for 2D instance segmentation, 3D instance segmentation still faces critical challenges, such as insufficient…

Computer Vision and Pattern Recognition · Computer Science 2018-07-02 Zhuo Zhao , Lin Yang , Hao Zheng , Ian H. Guldner , Siyuan Zhang , Danny Z. Chen

Weakly supervised instance labeling using only image-level labels, in lieu of expensive fine-grained pixel annotations, is crucial in several applications including medical image analysis. In contrast to conventional instance segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Jayaraman J. Thiagarajan , Satyananda Kashyap , Alexandros Karagyris

Pathologists comprehensive evaluation of donor liver biopsies provides crucial information for accepting or discarding potential grafts. However, rapidly and accurately obtaining these assessments intraoperatively poses a significant…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Liangrui Pan , Xingchen Li , Zhongyi Chen , Ling Chu , Shaoliang Peng

PET-CT lesion segmentation is challenging due to noise sensitivity, small and variable lesion morphology, and interference from physiological high-metabolic signals. Current mainstream approaches follow the practice of one network solving…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Xinglong Liang , Jiaju Huang , Luyi Han , Tianyu Zhang , Xin Wang , Yuan Gao , Chunyao Lu , Lishan Cai , Tao Tan , Ritse Mann

Mitotic figure detection remains a challenging task in computational pathology due to domain variability and morphological complexity. This paper describes our participation in the MIDOG 2025 challenge, focusing on robust mitotic figure…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Euiseop Song , Jaeyoung Park , Jaewoo Park

Extracting single-cell information from microscopy data requires accurate instance-wise segmentations. Obtaining pixel-wise segmentations from microscopy imagery remains a challenging task, especially with the added complexity of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-02 Christoph Reich , Tim Prangemeier , André O. Françani , Heinz Koeppl

The representative instance segmentation methods mostly segment different object instances with a mask of the fixed resolution, e.g., 28*28 grid. However, a low-resolution mask loses rich details, while a high-resolution mask incurs…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Ruihuang Li , Chenhang He , Shuai Li , Yabin Zhang , Lei Zhang

Instance-level human analysis is common in real-life scenarios and has multiple manifestations, such as human part segmentation, dense pose estimation, human-object interactions, etc. Models need to distinguish different human instances in…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Lu Yang , Qing Song , Zhihui Wang , Ming Jiang

Breast cancer is a major concern for women's health globally, with axillary lymph node (ALN) metastasis identification being critical for prognosis evaluation and treatment guidance. This paper presents a deep learning (DL) classification…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Glejdis Shkëmbi , Johanna P. Müller , Zhe Li , Katharina Breininger , Peter Schüffler , Bernhard Kainz

Breast cancer is one of the most common and dangerous cancers in women, while it can also afflict men. Breast cancer treatment and detection are greatly aided by the use of histopathological images since they contain sufficient phenotypic…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Md Ishtyaq Mahmud , Muntasir Mamun , Ahmed Abdelgawad

Objective: A new image instance segmentation method is proposed to segment individual glands (instances) in colon histology images. This process is challenging since the glands not only need to be segmented from a complex background, they…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Yan Xu , Yang Li , Yipei Wang , Mingyuan Liu , Yubo Fan , Maode Lai , Eric I-Chao Chang

Breast cancer is the most common cancer in the world and the second most common type of cancer that causes death in women. The timely and accurate diagnosis of breast cancer using histopathological images is crucial for patient care and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Amira Alotaibi , Tarik Alafif , Faris Alkhilaiwi , Yasser Alatawi , Hassan Althobaiti , Abdulmajeed Alrefaei , Yousef M Hawsawi , Tin Nguyen

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…

It is of great significance to diagnose Invasive Ductal Carcinoma (IDC) in early stage, which is the most common subtype of breast cancer. Although the powerful models in the Computer-Aided Diagnosis (CAD) systems provide promising results,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Yujia Lin , Aiwei Lian , Mingyu Liao , Shuangjie Yuan

Cervical cancer remains a significant global health concern and a leading cause of cancer-related deaths among women. Early detection through Pap smear tests is essential to reduce mortality rates; however, the manual examination is time…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nisreen Albzour , Sarah S. Lam

Image saliency detection has recently witnessed rapid progress due to deep convolutional neural networks. However, none of the existing methods is able to identify object instances in the detected salient regions. In this paper, we present…

Computer Vision and Pattern Recognition · Computer Science 2017-04-13 Guanbin Li , Yuan Xie , Liang Lin , Yizhou Yu

Semantic segmentation of medical images is an essential first step in computer-aided diagnosis systems for many applications. However, given many disparate imaging modalities and inherent variations in the patient data, it is difficult to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Bhavani Sambaturu , Ashutosh Gupta , C. V. Jawahar , Chetan Arora

In this paper, we propose a novel image descriptor called Forming Local Intersections of Projections (FLIP) and its multi-resolution version (mFLIP) for representing histopathology images. The descriptor is based on the Radon transform…

Computer Vision and Pattern Recognition · Computer Science 2020-08-11 Aditya Sriram , Shivam Kalra , Morteza Babaie , Brady Kieffer , Waddah Al Drobi , Shahryar Rahnamayan , Hany Kashani , Hamid R. Tizhoosh