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The application of systems and control theory to membrane physiology is presented here. Modeling efforts have focused on describing those physiologically realistic mechanisms which govern the regulation of membrane permeability in nerve.…

Biological Physics · Physics 2021-09-29 Robert F. Melendy

Experimental evidences have shown that graphene oxide (GO) can be impermeable to liquids, vapors and gases, while it allows a fast permeation of water molecules. The understanding of filtration mechanisms came mostly from studies dedicated…

Mesoscale and Nanoscale Physics · Physics 2017-06-21 Daiane Damasceno Borges , Cristiano F. Woellner , Pedro A. S. Autreto , Douglas S. Galvao

The behaviour of a system of ion channels formed across the cell membrane is presented. The infinite number of channels with an infinite coupling is introduced first as a reference point for the detailed derivation of the…

Biological Physics · Physics 2007-05-23 Adam Rycerz

We combine quantum-chemical calculations and molecular dynamics simulations to consider aqueous ion flow across non-axisymmetric nanopores in monolayer graphene and MoS$_2$. When the pore-containing membrane is subject to uniaxial tensile…

Applied Physics · Physics 2020-04-30 A. Smolyanitsky , A. Fang , A. F. Kazakov , E. Paulechka

Metasurfaces are promising two-dimensional metamaterials that are engineered to provide unique properties or functionalities absent in naturally occurring homogeneous surfaces. Here, we report a type of metasurface for tailored…

Optics · Physics 2014-05-21 Jiao Lin , Qian Wang , Guanghui Yuan , Luping Du , Shan Shan Kou , Xiao-Cong Yuan

Ion channels are membrane proteins responsible for an enormous range of biological functions. Ion selectivity and permeation are based on simple laws of physics and chemistry. Ion channels are therefore ideal candidates for physical…

Biological Physics · Physics 2012-06-14 Janhavi Giri

The extraordinary electronic properties of graphene, such as its continuously gate-variable ambipolar field effect and the resulting steep change in resistivity, provided the main thrusts for the rapid advance of graphene electronics. The…

Ionic transport in nano- to sub-nano-scale pores is highly dependent on translocation barriers and potential wells. These features in the free-energy landscape are primarily the result of ion dehydration and electrostatic interactions. For…

Mesoscale and Nanoscale Physics · Physics 2020-12-01 Subin Sahu , Michael Zwolak

Membranes are present in all cells and tissues. Mathematical models of cells and tissues need a compact mathematical description of membranes with a resolution of about 1 nm. Membranes isolate cells because ions have difficulty penetrating…

Dynamical Systems · Mathematics 2021-06-01 Yi Zhu , Shixin Xu , Robert S. Eisenberg , Huaxiong Huang

Excitability is an attribute of life, and is a driving force in the descent of complexity. Cellular electrical activity as realized by membrane proteins that act as either channels or transporters is the basis of excitability. Electrical…

Biomolecules · Quantitative Biology 2009-11-05 Ashok Palaniappan , Eric Jakobsson

This work introduces a concept of origami electronic membranes that leverages the design and fabrication of flexible electronics and the mechanical behavior of engineering origami to achieve unique multifunctional, shape-reconfigurable, and…

Applied Physics · Physics 2024-06-13 Yao Yao , Guanghui Li , Xin Ning

Synaptic plasticity, the dynamic tuning of signal transmission strength between neurons, serves as a fundamental basis for memory and learning in biological organisms. This adaptive nature of synapses is considered one of the key features…

Mesoscale and Nanoscale Physics · Physics 2024-11-11 Yechan Noh , Alex Smolyanitsky

The suite of highly confined polaritons supported by two-dimensional (2D) materials constitutes a versatile platform for nano-optics, offering the means to channel light on deep-subwavelength scales. Graphene, in particular, has attracted…

Mesoscale and Nanoscale Physics · Physics 2021-08-11 T. P. Rasmussen , P. A. D. Gonçalves , Sanshui Xiao , Sebastian Hofferberth , N. Asger Mortensen , Joel D. Cox

Cellular decision-making based on information received from the external environment is frequently initiated by transmembrane receptors. These receptors are known to propagate such information by triggering a series of irreversible,…

Biological Physics · Physics 2026-05-13 Samuel L. Foley , Margaret E. Johnson

Diffusion rates through a membrane can be asymmetric, if the diffusing particles are spatially extended and the pores in the membrane have asymmetric structure. This phenomenon is demonstrated here via a deterministic simulation of a…

Statistical Mechanics · Physics 2007-05-23 Norman Packard , Rob Shaw

Biological membranes are essential for the cell life and hydration water provides the driving force for their assembly and stability. Here we study the structural properties of water in a phospholipid membrane. We characterize local…

Soft Condensed Matter · Physics 2017-03-24 Fausto Martelli , Hsin-Yu Ko , Carles Calero Borallo , Giancarlo Franzese

Lipid membranes, the barrier defining living cells and many of their sub-compartments, bind to a wide variety of nano- and micro-meter sized objects. In the presence of strong adhesive forces, membranes can strongly deform and wrap the…

The electropermeabilization of biological cell membranes by the application of an external field occurs whenever an applied field exceeds a threshold value. For fields above this threshold value but less than another critical value, the…

Biological Physics · Physics 2007-05-23 William A. Hercules , James Lindesay , Anna Coble , Robert Schmukler

The interaction between nano- or micro-sized particles and cell membranes is of crucial importance in many biological and biomedical applications such as drug and gene delivery to cells and tissues. During their cellular uptake, the…

Membrane proteins constitute a large portion of the human proteome and perform a variety of important functions as membrane receptors, transport proteins, enzymes, signaling proteins, and more. The computational studies of membrane proteins…

Biological Physics · Physics 2017-04-25 Li Xiao , Jianxiong Diao , D Artagnan Greene , Junmei Wang , Ray Luo