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Glioblastoma Multiforme is a high grade, very aggressive, brain tumor, with patients having a poor prognosis. Lower grade gliomas are less aggressive, but they can evolve into higher grade tumors over time. Patient management and treatment…

Computer Vision and Pattern Recognition · Computer Science 2018-11-01 Sergio Pereira , Raphael Meier , Victor Alves , Mauricio Reyes , Carlos A. Silva

Histopathological assessments, including surgical resection and core needle biopsy, are the standard procedures in the diagnosis of the prostate cancer. Current interpretation of the histopathology images includes the determination of the…

Computer Vision and Pattern Recognition · Computer Science 2017-05-12 Naiyun Zhou , Andrey Fedorov , Fiona Fennessy , Ron Kikinis , Yi Gao

Convolutional Neural Networks (CNNs) have been used for automated detection of prostate cancer where Area Under Receiver Operating Characteristic (ROC) curve (AUC) is usually used as the performance metric. Given that AUC is not…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Khashayar Namdar , Isha Gujrathi , Masoom A. Haider , Farzad Khalvati

Drug overdose deaths, including those due to prescription opioids, represent a critical public health issue in the United States and worldwide. Artificial intelligence (AI) approaches have been developed and deployed to help prescribers…

Human-Computer Interaction · Computer Science 2025-02-18 Venkatesh Sivaraman , Yejun Kwak , Courtney Kuza , Qingnan Yang , Kayleigh Adamson , Katie Suda , Lu Tang , Walid Gellad , Adam Perer

Computer-aided segmentation of brain tumors from MRI data is of crucial significance to clinical decision-making in diagnosis, treatment planning, and follow-up disease monitoring. Gliomas, owing to their high malignancy and heterogeneity,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 MD Rashidul Islam , Bakary Gibba

Prostate cancer is the second deadliest cancer for American men. While Magnetic Resonance Imaging (MRI) is increasingly used to guide targeted biopsies for prostate cancer diagnosis, its utility remains limited due to high rates of false…

In 2020, prostate cancer saw a staggering 1.4 million new cases, resulting in over 375,000 deaths. The accurate identification of clinically significant prostate cancer is crucial for delivering effective treatment to patients.…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Chi-en Amy Tai , Alexander Wong

Background: Real-time treatment planning in IMRT is challenging due to complex beam interactions. AI has improved automation, but existing models require large, high-quality datasets and lack universal applicability. Deep reinforcement…

Medical Physics · Physics 2025-02-26 Md Mainul Abrar , Parvat Sapkota , Damon Sprouts , Xun Jia , Yujie Chi

Current prognostic risk scores in cardiac surgery are based on statistics and do not yet benefit from machine learning. Statistical predictors are not robust enough to correctly identify patients who would benefit from Transcatheter Aortic…

Machine Learning · Computer Science 2020-01-09 Marco Mamprin , Jo M. Zelis , Pim A. L. Tonino , Svitlana Zinger , Peter H. N. de With

Spitz tumors are diagnostically challenging due to overlap in atypical histological features with conventional melanomas. We investigated to what extent AI models, using histological and/or clinical features, can: (1) distinguish Spitz…

Comparative diagnostic in brain tumor evaluation makes possible to use the available information of a medical center to compare similar cases when a new patient is evaluated. By leveraging Artificial Intelligence models, the proposed system…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Guillermo Iglesias , Edgar Talavera , Jesús Troya Garcìa , Alberto Díaz-Álvarez , Miguel Gracía-Remesal

This research presents an innovative approach to cancer diagnosis and prediction using explainable Artificial Intelligence (XAI) and deep learning techniques. With cancer causing nearly 10 million deaths globally in 2020, early and accurate…

Artificial Intelligence · Computer Science 2024-12-24 Badaru I. Olumuyiwa , The Anh Han , Zia U. Shamszaman

Lung cancer is the primary cause of cancer-related mortality, claiming approximately 1.79 million lives globally in 2020, with an estimated 2.21 million new cases diagnosed within the same period. Among these, Non-Small Cell Lung Cancer…

Quantitative Methods · Quantitative Biology 2024-02-16 Mahtab Darvish , Ryan Trask , Patrick Tallon , Mélina Khansari , Lei Ren , Michelle Hershman , Bardia Yousefi

Objective: We compared six commonly used logistic regression methods for accommodating missing risk factor data from multiple heterogeneous cohorts, in which some cohorts do not collect some risk factors at all, and developed an online risk…

In recent years, the diagnosis of gliomas has become increasingly complex. Analysis of glioma histopathology images using artificial intelligence (AI) offers new opportunities to support diagnosis and outcome prediction. To give an overview…

Adverse drug reactions considerably impact patient outcomes and healthcare costs in cancer therapy. Using artificial intelligence to predict adverse drug reactions in real time could revolutionize oncology treatment. This study aims to…

Quantitative Methods · Quantitative Biology 2025-05-21 Fatma Zahra Abdeldjouad , Menaouer Brahami , Mohammed Sabri

Northern Europe has the second highest mortality rate of melanoma globally. In 2020, the mortality rate of melanoma rose to 1.9 per 100 000 habitants. Melanoma prognosis is based on a pathologist's subjective visual analysis of the…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Christopher Andreassen , Saul Fuster , Helga Hardardottir , Emiel A. M. Janssen , Kjersti Engan

Accurate prediction of biochemical recurrence (BCR) after radical prostatectomy is critical for guiding adjuvant treatment and surveillance decisions in prostate cancer. However, existing clinicopathological risk models reduce complex…

Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

For head and neck cancer (HNC) patients, prognostic outcome prediction can support personalized treatment strategy selection. Improving prediction performance of HNC outcomes has been extensively explored by using advanced artificial…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Baoqiang Ma , Djennifer K. Madzia-Madzou , Rosa C. J. Kraaijveld , Jin Ouyang
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