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Despite the growing interest in human-AI decision making, experimental studies with domain experts remain rare, largely due to the complexity of working with domain experts and the challenges in setting up realistic experiments. In this…

Automated grading of prostate cancer histopathology images is a challenging task, with one key challenge being the scarcity of annotations down to the level of regions of interest (strong labels), as typically the prostate cancer Gleason…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Eirini Arvaniti , Manfred Claassen

The Gleason scoring system is the primary diagnostic and prognostic tool for prostate cancer. In recent years, with the development of digitisation devices, the use of computer vision techniques for the analysis of biopsies has increased.…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Julio Silva-Rodríguez , Adrián Colomer , María A. Sales , Rafael Molina , Valery Naranjo

Tissue detection is a crucial first step in most digital pathology applications. Details of the segmentation algorithm are rarely reported, and there is a lack of studies investigating the downstream effects of a poor segmentation…

Background: Artificial intelligence (AI) is improving the efficiency and accuracy of cancer diagnostics. The performance of pathology AI systems has been almost exclusively evaluated on European and US cohorts from large centers. For global…

Histology-based grade classification is clinically important for many cancer types in stratifying patients distinct treatment groups. In prostate cancer, the Gleason score is a grading system used to measure the aggressiveness of prostate…

Computer Vision and Pattern Recognition · Computer Science 2019-11-07 Jingwen Wang , Richard J. Chen , Ming Y. Lu , Alexander Baras , Faisal Mahmood

Multiparametric magnetic resonance imaging (mp-MRI) has shown excellent results in the detection of prostate cancer (PCa). However, characterizing prostate lesions aggressiveness in mp-MRI sequences is impossible in clinical practice, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Audrey Duran , Gaspard Dussert , Olivier Rouvière , Tristan Jaouen , Pierre-Marc Jodoin , Carole Lartizien

Background and objective: Micro-ultrasound (micro-US) is a novel imaging modality with diagnostic accuracy comparable to MRI for detecting clinically significant prostate cancer (csPCa). We investigated whether artificial intelligence (AI)…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Muhammad Imran , Wayne G. Brisbane , Li-Ming Su , Jason P. Joseph , Wei Shao

Prostate cancer (Pca) continues to be a leading cause of cancer-related mortality in men, and the limitations in precision of traditional diagnostic methods such as the Digital Rectal Exam (DRE), Prostate-Specific Antigen (PSA) testing, and…

Artificial intelligence may assist healthcare systems in meeting increasing demand for pathology services while maintaining diagnostic quality and reducing turnaround time and costs. We aimed to investigate the performance of an…

Prostate cancer is one of the most frequently diagnosed malignancies in men worldwide. However, precise prediction of biochemical recurrence (BCR) after radical prostatectomy remains challenging due to the multifocality of tumors…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yesung Cho , Dongmyung Shin , Sujeong Hong , Jooyeon Lee , Seongmin Park , Geongyu Lee , Jongbae Park , Hong Koo Ha

Pancreatic cancers have one of the worst prognoses compared to other cancers, as they are diagnosed when cancer has progressed towards its latter stages. The current manual histological grading for diagnosing pancreatic adenocarcinomas is…

Image and Video Processing · Electrical Eng. & Systems 2022-06-20 Biraja Ghoshal , Bhargab Ghoshal , Allan Tucker

Prostate cancer (PCa) is one of the most common cancers in men around the world. The most accurate method to evaluate lesion levels of PCa is microscopic inspection of stained biopsy tissue and estimate the Gleason score of tissue…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Yi-hong Zhang , Jing Zhang , Yang Song , Chaomin Shen , Guang Yang

Prostate cancer is one of the main diseases affecting men worldwide. The gold standard for diagnosis and prognosis is the Gleason grading system. In this process, pathologists manually analyze prostate histology slides under microscope, in…

Image and Video Processing · Electrical Eng. & Systems 2021-05-24 Julio Silva-Rodríguez , Adrián Colomer , Jose Dolz , Valery Naranjo

The emergence of multi-parametric magnetic resonance imaging (mpMRI) has had a profound impact on the diagnosis of prostate cancers (PCa), which is the most prevalent malignancy in males in the western world, enabling a better selection of…

Active surveillance (AS) is a suitable management option for newly-diagnosed prostate cancer (PCa), which usually presents low to intermediate clinical risk. Patients enrolled in AS have their tumor closely monitored via longitudinal…

We investigate the connection between visual semantic features defined in PI-RADS and associated risk factors, moving beyond abnormal imaging findings, establishing a shared framework between medical and AI professionals by creating a…

Biochemical recurrence (BCR) after radical prostatectomy (RP) is a surrogate marker for aggressive prostate cancer with adverse outcomes, yet current prognostic tools remain imprecise. We trained an AI-based model on diagnostic prostate…

Artificial intelligence systems show promise to aid in the di- agnostic pathway of prostate cancer (PC), by supporting radiologists in interpreting magnetic resonance images (MRI) of the prostate. Most MRI-based systems are designed to…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Erlend Sortland Rolfsnes , Philip Thangngat , Trygve Eftestøl , Tobias Nordström , Fredrik Jäderling , Martin Eklund , Alvaro Fernandez-Quilez

Colorectal cancer is the third most common tumor in men and the second in women, accounting for 10% of all tumors worldwide. It ranks second in cancer-related deaths with 9.4%, following lung cancer. The decrease in mortality rate…

Other Quantitative Biology · Quantitative Biology 2022-09-27 Panagiotis Katrakazas , Aristotelis Ballas , Marco Anisetti , Ilias Spais