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We assess the potential of quantum computing to accelerate computation of central tasks in genomics, focusing on often-neglected theoretical limitations. We discuss state-of-the-art challenges of quantum search, optimization, and machine…

Quantum Physics · Physics 2026-01-09 Aurora Maurizio , Guglielmo Mazzola

We discuss the performance of the Search and Fourier Transform algorithms on a hybrid computer constituted of classical and quantum processors working together. We show that this semi-quantum computer would be an improvement over a pure…

Quantum Physics · Physics 2007-05-23 Reinaldo O. Vianna , Wilson R. M. Rabelo , C. H. Monken

The development of tailored materials for specific applications is an active field of research in chemistry, material science and drug discovery. The number of possible molecules that can be obtained from a set of atomic species grow…

The development of advanced quantum-classical algorithms is among the most prominent strategies in quantum computing. Numerous hybrid solvers have been introduced recently. Many of these methods are created ad hoc to address specific use…

Emerging Technologies · Computer Science 2024-12-05 Eneko Osaba , Pablo Miranda-Rodriguez

Quantum computers provide a fundamentally new computing paradigm that promises to revolutionize our ability to solve broad classes of problems. Surprisingly, the basic mathematical structures of gate-based quantum computing, such as unitary…

Quantum Physics · Physics 2019-08-20 Brian R. La Cour , S. Andrew Lanham , Corey I. Ostrove

Quantum computers use the quantum interference of different computational paths to enhance correct outcomes and suppress erroneous outcomes of computations. In effect, they follow the same logical paradigm as (multi-particle)…

Quantum Physics · Physics 2007-05-23 R. Cleve , A. Ekert , L. Henderson , C. Macchiavello , M. Mosca

We propose a quantum heuristic algorithm to solve a traveling salesman problem by generalizing Grover search. Sufficient conditions are derived to greatly enhance the probability of finding the tours with extremal costs, reaching almost to…

Quantum Physics · Physics 2013-01-08 Jeongho Bang , Seokwon Yoo , James Lim , Junghee Ryu , Changhyoup Lee , Jinhyoung Lee

Quantum computing is a new model of computation, based on quantum physics. Quantum computers can be exponentially faster than conventional computers for problems such as factoring. Besides full-scale quantum computers, more restricted…

Formal Languages and Automata Theory · Computer Science 2018-07-05 Andris Ambainis , Abuzer Yakaryılmaz

Quantum computing comes with the potential to push computational boundaries in various domains including, e.g., cryptography, simulation, optimization, and machine learning. Exploiting the principles of quantum mechanics, new algorithms can…

Systems and Control · Electrical Eng. & Systems 2025-12-23 Julian Berberich , Robert L. Kosut , Thomas Schulte-Herbrüggen

Quantum computing is changing the way we think about computing. Significant strides in research and development for managing and harnessing the power of quantum systems has been made in recent years, demonstrating the potential for…

Quantum Physics · Physics 2022-11-15 Suryansh Upadhyay , Mahabubul Alam , Swaroop Ghosh

The Travelling Salesman Problem (TSP) is an important combinatorial optimisation problem, and is usually solved on a quantum computer using a Quadratic Unconstrained Binary Optimisation (QUBO) formulation or a Higher Order Binary…

Quantum Physics · Physics 2024-06-21 Daniel Goldsmith , Joe Day-Evans

Quantum computing is a fascinating interdisciplinary research field that promises to revolutionize computing by efficiently solving previously intractable problems. Recent years have seen tremendous progress on both the experimental…

Systems and Control · Electrical Eng. & Systems 2024-12-04 Julian Berberich , Daniel Fink

We present a quantum annealing-based solution method for topology optimization (TO). In particular, we consider TO in a more general setting, i.e., applied to structures of continuum domains where designs are represented as distributed…

Numerical Analysis · Mathematics 2023-01-30 Zisheng Ye , Xiaoping Qian , Wenxiao Pan

We present a quantum algorithm for combinatorial optimization using the cost structure of the search states. Its behavior is illustrated for overconstrained satisfiability and asymmetric traveling salesman problems. Simulations with…

Quantum Physics · Physics 2007-05-23 Tad Hogg , Dmitriy Portnov

To overcome the physical limitations of scaling monolithic quantum computers, distributed quantum computing (DQC) interconnects multiple smaller-scale quantum processing units (QPUs) to form a quantum network. However, this approach…

Quantum computing has the potential to revolutionize multiple fields by solving complex problems that can not be solved in reasonable time with current classical computers. Nevertheless, the development of quantum computers is still in its…

This paper presents the details and testing of two implementations (in C++ and Python) of the hybrid quantum-classical algorithm Quantum Annealing Learning Search (QALS) on a D-Wave quantum annealer. QALS was proposed in 2019 as a novel…

Emerging Technologies · Computer Science 2022-12-22 Andrea Bonomi , Thomas De Min , Enrico Zardini , Enrico Blanzieri , Valter Cavecchia , Davide Pastorello

The NP-complete problem of the travelling salesman (TSP) is considered in the framework of quantum adiabatic computation (QAC). We first derive a remarkable lower bound for the computation time for adiabatic algorithms in general as a…

Quantum Physics · Physics 2007-05-23 Tien D. Kieu

Quantum computing promises significant speed-ups for certain algorithms but the practical use of current noisy intermediate-scale quantum (NISQ) era computers remains limited by resources constraints (e.g., noise, qubits, gates, and circuit…

Quantum Physics · Physics 2026-03-31 Tobias Fischbach , Pierre Talbot , Pascal Bouvry

Quantum annealing is a computational paradigm in which optimisation problems are mapped onto the energy landscape of an interacting quantum system and explored through its dynamical evolution. By continuously transforming a simple initial…

Quantum Physics · Physics 2026-05-11 Steven Abel , Andrei Constantin , Luca A. Nutricati