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Kidney Exchange Programs (KEPs) promote access to living donor trans- plantation for patients suffering from end stage renal disease. The HLA compatibility between transplant recipients and donors plays an important role when solving the…

Optimization and Control · Mathematics 2025-10-17 Valentina Peralta Clarke , Hans de Ferrante , Francisco Perez Galarce , Joris van de Klundert

In barter exchanges, participants swap goods with one another without exchanging money; exchanges are often facilitated by a central clearinghouse, with the goal of maximizing the aggregate quality (or number) of swaps. Barter exchanges are…

Artificial Intelligence · Computer Science 2020-10-26 Duncan C McElfresh , Michael Curry , Tuomas Sandholm , John P Dickerson

In kidney exchange programs, multiple patient-donor pairs each of whom are otherwise incompatible, exchange their donors to receive compatible kidneys. The Kidney Exchange problem is typically modelled as a directed graph where every vertex…

Computer Science and Game Theory · Computer Science 2024-06-17 Arnab Maiti , Palash Dey

The Kidney Exchange Problem is a prominent challenge in healthcare and economics, arising in the context of organ transplantation. It has been extensively studied in artificial intelligence and optimization. In a kidney exchange, a set of…

Data Structures and Algorithms · Computer Science 2026-05-12 Kangyi Tian , Mingyu Xiao

Kidney exchanges are organized markets where patients swap willing but incompatible donors. In the last decade, kidney exchanges grew from small and regional to large and national---and soon, international. This growth results in more lives…

Artificial Intelligence · Computer Science 2016-12-19 John P. Dickerson , Aleksandr M. Kazachkov , Ariel D. Procaccia , Tuomas Sandholm

Kidney donations from living donors form an attractive alternative to long waiting times on a list for a post-mortem donation. However, even if a living donor for a given patient is found, the donor's kidney might not meet the patient's…

Cryptography and Security · Computer Science 2020-11-11 Malte Breuer , Ulrike Meyer , Susanne Wetzel , Anja Mühlfeld

The kidney exchange mechanism allows many patient-donor pairs who are otherwise incompatible with each other to come together and exchange kidneys along a cycle. However, due to infrastructure and legal constraints, kidney exchange can only…

Data Structures and Algorithms · Computer Science 2026-01-01 Aritra Banik , Sujoy Bhore , Palash Dey , Abhishek Sahu

Motivated by kidney exchange, we study a stochastic cycle and chain packing problem, where we aim to identify structures in a directed graph to maximize the expectation of matched edge weights. All edges are subject to failure, and the…

Artificial Intelligence · Computer Science 2020-07-08 Hoda Bidkhori , John P Dickerson , Duncan C McElfresh , Ke Ren

We introduce the Stackelberg kidney exchange problem. In this problem, an agent (e.g. a hospital or a national organization) has control over a number of incompatible patient-donor pairs whose patients are in need of a transplant. The agent…

Computer Science and Game Theory · Computer Science 2020-07-08 Bart Smeulders , Danny Blom , Frits C. R. Spieksma

In barter exchanges, participants directly trade their endowed goods in a constrained economic setting without money. Transactions in barter exchanges are often facilitated via a central clearinghouse that must match participants even in…

Artificial Intelligence · Computer Science 2018-11-09 Duncan C McElfresh , Hoda Bidkhori , John P Dickerson

This paper introduces a new learning-based approach for approximately solving the Kidney-Exchange Problem (KEP), an NP-hard problem on graphs. The problem consists of, given a pool of kidney donors and patients waiting for kidney donations,…

Machine Learning · Computer Science 2023-04-21 Pedro Foletto Pimenta , Pedro H. C. Avelar , Luis C. Lamb

A kidney exchange is a centrally-administered barter market where patients swap their willing yet incompatible donors. Modern kidney exchanges use 2-cycles, 3-cycles, and chains initiated by non-directed donors (altruists who are willing to…

Computer Science and Game Theory · Computer Science 2017-05-29 Gabriele Farina , John P. Dickerson , Tuomas Sandholm

Kidney transplants are sharply overdemanded in the United States. A recent innovation to address organ shortages is a kidney exchange, in which willing but medically incompatible patient-donor pairs swap donors so that two successful…

Computer Science and Game Theory · Computer Science 2019-12-24 Irena Gao

A kidney exchange program, also called a kidney paired donation program, can be viewed as a repeated, dynamic trading and allocation mechanism. This suggests that a dynamic algorithm for transplant exchange selection may have superior…

Optimization and Control · Mathematics 2023-09-26 Margarida Carvalho , Alison Caulfield , Yi Lin , Adrian Vetta

Kidney exchange is a barter market where patients trade willing but medically incompatible donors. These trades occur via cycles, where each patient-donor pair both gives and receives a kidney, and via chains, which begin with an altruistic…

Data Structures and Algorithms · Computer Science 2016-06-02 Benjamin Plaut , John P. Dickerson , Tuomas Sandholm

To this day, there are still some countries where the exchange of kidneys between multiple incompatible patient-donor pairs is restricted by law. Typically, legal regulations in this context are put in place to prohibit coercion and…

Cryptography and Security · Computer Science 2022-06-03 Malte Breuer , Ulrike Meyer , Susanne Wetzel

The kidney paired donation (KPD) program provides an innovative solution to overcome incompatibility challenges in kidney transplants by matching incompatible donor-patient pairs and facilitating kidney exchanges. To address unequal access…

Methodology · Statistics 2026-01-21 Mingrui Zhang , Xiaowu Dai , Lexin Li

We study an elementary path problem which appears in the pricing step of a column generation scheme solving the kidney exchange problem. The latter aims at finding exchanges of donations in a pool of patients and donors of kidney…

Data Structures and Algorithms · Computer Science 2022-01-24 Lucie Pansart , Hadrien Cambazard , Nicolas Catusse

Motivated by the real-world problem of international kidney exchange (IKEP), recent literature introduced a generalized transferable utility matching game featuring a partition of the vertex set of a graph into players, and analyzed its…

Computer Science and Game Theory · Computer Science 2026-02-24 Gergely Csáji , Tamás Király , Zsuzsa Mészáros-Karkus

Relatives and friends of an end-stage renal disease patient who offer to donate a kidney are often found to be incompatible with their intended recipients. Kidney paired donation matches one patient and his incompatible donor with another…

Computer Science and Game Theory · Computer Science 2017-10-24 Sommer Gentry , Michal Mankowski , T. S. Michael , Dorry Segev