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Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

A distinct feature of pancreatic ductal adenocarcinoma (PDAC) is a prominent tumor microenvironment (TME) with remarkable cellular and spatial heterogeneity that meaningfully impacts disease biology and treatment resistance. The dynamic…

Intraductal papillary mucinous neoplasm (IPMN) is a precursor to pancreatic ductal adenocarcinoma. While over half of patients are diagnosed with pancreatic cancer at a distant stage, patients who are diagnosed early enjoy a much higher…

Computer Vision and Pattern Recognition · Computer Science 2019-07-02 Rodney LaLonde , Irene Tanner , Katerina Nikiforaki , Georgios Z. Papadakis , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

Automatic segmentation of medical images is an important task for many clinical applications. In practice, a wide range of anatomical structures are visualised using different imaging modalities. In this paper, we investigate whether a…

Computer Vision and Pattern Recognition · Computer Science 2017-04-12 Pim Moeskops , Jelmer M. Wolterink , Bas H. M. van der Velden , Kenneth G. A. Gilhuijs , Tim Leiner , Max A. Viergever , Ivana Išgum

Pancreatic NEuroendocrine Tumors (pNETs) are very rare endocrine neoplasms that account for less than 5% of all pancreatic malignancies, with an incidence of only 1-1.5 cases per 100,000. Early detection of pNETs is critical for improving…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Wenqi Li , Yingli Chen , Keyang Zhou , Xiaoxiao Hu , Zilu Zheng , Yue Yan , Xinpeng Zhang , Wei Tang , Zhenxing Qian

Timely and accurate diagnosis of appendicitis is critical in clinical settings to prevent serious complications. While CT imaging remains the standard diagnostic tool, the growing number of cases can overwhelm radiologists, potentially…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Chia-Wen Huang , Haw Hwai , Chien-Chang Lee , Pei-Yuan Wu

Manual or automatic delineation of the esophageal tumor in CT images is known to be very challenging. This is due to the low contrast between the tumor and adjacent tissues, the anatomical variation of the esophagus, as well as the…

We present an efficient deep learning approach for the challenging task of tumor segmentation in multisequence MR images. In recent years, Convolutional Neural Networks (CNN) have achieved state-of-the-art performances in a large variety of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Automatic segmentation of abdomen organs using medical imaging has many potential applications in clinical workflows. Recently, the state-of-the-art performance for organ segmentation has been achieved by deep learning models, i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2019-10-16 Jinzheng Cai , Yingda Xia , Dong Yang , Daguang Xu , Lin Yang , Holger Roth

Current state-of-the-art deep learning segmentation methods have not yet made a broad entrance into the clinical setting in spite of high demand for such automatic methods. One important reason is the lack of reliability caused by models…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Jörg Sander , Bob D. de Vos , Jelmer M. Wolterink , Ivana Išgum

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Ran Gu , Guotai Wang , Tao Song , Rui Huang , Michael Aertsen , Jan Deprest , Sébastien Ourselin , Tom Vercauteren , Shaoting Zhang

PET-CT lesion segmentation is challenging due to noise sensitivity, small and variable lesion morphology, and interference from physiological high-metabolic signals. Current mainstream approaches follow the practice of one network solving…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Xinglong Liang , Jiaju Huang , Luyi Han , Tianyu Zhang , Xin Wang , Yuan Gao , Chunyao Lu , Lishan Cai , Tao Tan , Ritse Mann

Accurate and robust segmentation of abdominal organs on CT is essential for many clinical applications such as computer-aided diagnosis and computer-aided surgery. But this task is challenging due to the weak boundaries of organs, the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Yan Wang , Yuyin Zhou , Wei Shen , Seyoun Park , Elliot K. Fishman , Alan L. Yuille

Non-invasive detection of cardiovascular disorders from radiology scans requires quantitative image analysis of the heart and its substructures. There are well-established measurements that radiologists use for diseases assessment such as…

Machine Learning · Statistics 2017-08-04 Aliasghar Mortazi , Jeremy Burt , Ulas Bagci

For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice manner conventionally use the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenxuan Wang , Chen Chen , Jing Wang , Sen Zha , Yan Zhang , Jiangyun Li

With the significantly increasing incidence and prevalence of abdominal diseases, there is a need to embrace greater use of new innovations and technology for the diagnosis and treatment of patients. Although deep-learning methods have…

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

Clinical data elements (CDEs) (e.g., age, smoking history), blood markers and chest computed tomography (CT) structural features have been regarded as effective means for assessing lung cancer risk. These independent variables can provide…

Image and Video Processing · Electrical Eng. & Systems 2021-02-11 Riqiang Gao , Yucheng Tang , Kaiwen Xu , Michael N. Kammer , Sanja L. Antic , Steve Deppen , Kim L. Sandler , Pierre P. Massion , Yuankai Huo , Bennett A. Landman

Chronic Kidney Disease (CKD) constitutes a major global medical burden, marked by the gradual deterioration of renal function, which results in the impaired clearance of metabolic waste and disturbances in systemic fluid homeostasis. Owing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Anas Bin Ayub , Nilima Sultana Niha , Md. Zahurul Haque
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