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Modern statisticians are often presented with hundreds or thousands of hypothesis testing problems to evaluate at the same time, generated from new scientific technologies such as microarrays, medical and satellite imaging devices, or flow…

Applications · Statistics 2008-12-18 Bradley Efron

Due to the rapidly evolving COVID-19 pandemic caused by the SARS-CoV-2 virus, quick public health investigations of the relationships between behaviours and infection risk are essential. Recently the test-negative design was proposed to…

Methodology · Statistics 2021-02-09 Mireille E. Schnitzer , Daphna Harel , Vikki Ho , Anita Koushik , Joanna Merckx

Marketers often use A/B testing as a tool to compare marketing treatments in a test stage and then deploy the better-performing treatment to the remainder of the consumer population. While these tests have traditionally been analyzed using…

Applications · Statistics 2020-12-03 Elea McDonnell Feit , Ron Berman

In the United States, from the start of the COVID-19 pandemic to December 31, 2020, 341,199 deaths and more than 19,663,976 infections were recorded. Recent literature establishes that communities with poverty-related health problems, such…

Applications · Statistics 2021-02-09 Cesar R. Salas-Guerra

Economies across the globe were brought to their knees due to lockdowns and social restriction measures to contain the spread of the SARS-CoV-2, despite the quick switch to remote working. This downfall may be partially explained by the…

Multiagent Systems · Computer Science 2021-02-01 Peter Hardy , Leandro Soriano Marcolino , José F. Fontanari

In science as elsewhere, attention is a limited resource and scientists compete with one another to produce the most exciting, novel and impactful results. We develop a game-theoretic model to explore how such competition influences the…

Physics and Society · Physics 2025-09-09 Kevin Gross , Carl T. Bergstrom

Strong social distancing restrictions have been crucial to controlling the COVID-19 outbreak thus far, and the next question is when and how to relax these restrictions. A sequential timing of relaxing restrictions across groups is explored…

Populations and Evolution · Quantitative Biology 2020-05-14 Henry Zhao , Zhilan Feng , Carlos Castillo-Chavez , Simon A. Levin

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

The rapid spread of the new SARS-CoV-2 virus triggered a global health crisis disproportionately impacting people with pre-existing health conditions and particular demographic and socioeconomic characteristics. One of the main concerns of…

We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

Quantitative Methods · Quantitative Biology 2014-05-16 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

We present in this work some results from analysing the spread of Covid-19 in different countries and regions around the world and the potential relations with climate, geographical location, and GDP. While the situation remains dynamic, we…

Physics and Society · Physics 2020-04-21 Asit Kumar Mishra , Pawel Wargocki

The causal effect of a randomized job training program, the JOBS II study, on trainees' depression is evaluated. Principal stratification is used to deal with noncompliance to the assigned treatment. Due to the latent nature of the…

Applications · Statistics 2014-01-13 Alessandra Mattei , Fan Li , Fabrizia Mealli

In biology and ecology, individuals or communities of individuals living in unpredictable environments often alternate between different evolutionary strategies to spread and reduce risks. Such behavior is commonly referred to as…

Populations and Evolution · Quantitative Biology 2015-03-11 Jorge Hidalgo , Simone Pigolotti , Miguel A. Munoz

In this work, we aim to understand the influence of the heterogeneity of infection rates on the Susceptible-Infected-Susceptible (SIS) epidemic spreading. Employing the classic SIS model as the benchmark, we study the influence of the…

Physics and Society · Physics 2016-04-06 Bo Qu , Huijuan Wang

In this paper, we provide insights on how much testing and social distancing is required to control COVID-19. To this end, we develop a compartmental model that accounts for key aspects of the disease: 1) incubation time, 2) age-dependent…

Optimization and Control · Mathematics 2020-11-04 Sara Grundel , Stefan Heyder , Thomas Hotz , Tobias K. S. Ritschel , Philipp Sauerteig , Karl Worthmann

We introduce a two-timescale SIRS-type model in which a fraction $\theta$ of infected individuals experiences a severe course of the disease, requiring hospitalization. During hospitalization, these individuals do not contribute to further…

Dynamical Systems · Mathematics 2025-08-08 Jacopo Borsotti

Motivated by the importance of individual differences in risk perception and behavior change in people's responses to infectious disease outbreaks (particularly the ongoing COVID-19 pandemic), we propose a heterogeneous…

Physics and Society · Physics 2020-11-04 Yang Ye , Qingpeng Zhang , Zhongyuan Ruan , Zhidong Cao , Qi Xuan , Daniel Dajun Zeng

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in disjoint communities: each individual participates in a community, and its infection…

Information Theory · Computer Science 2021-03-18 Pavlos Nikolopoulos , Tao Guo , Sundara Rajan Srinivasavaradhan , Christina Fragouli , Suhas Diggavi

The controversy about statistical significance vs. scientific relevance is more than 100 years old. But still nowadays null hypothesis significance testing is considered as gold standard in many empirical fields from economics and social…

Applications · Statistics 2022-11-23 Uwe Hassler

Systemic liquidity risk, defined by the IMF as "the risk of simultaneous liquidity difficulties at multiple financial institutions", is a key topic in macroprudential policy and financial stress analysis. Specialized models to simulate…

Risk Management · Quantitative Finance 2021-12-08 V. Macchiati , G. Brandi , G. Cimini , G. Caldarelli , D. Paolotti , T. Di Matteo
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