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Background Information: Falls are associated with high direct and indirect costs, and significant morbidity and mortality for patients. Pathological falls are usually a result of a compromised motor system, and/or cognition. Very little…
Background: Many authors have described MELD as a predictor of short-term mortality in the liver transplantation waiting list. However MELD score accuracy to predict long term mortality has not been statistically evaluated. Objective: The…
In this paper, we propose the use of causal inference techniques for survival function estimation and prediction for subgroups of the data, upto individual units. Tree ensemble methods, specifically random forests were modified for this…
Background: Effective allocation of limited donor lungs in cystic fibrosis (CF) requires accurate survival predictions, so that high-risk patients may be prioritized for transplantation. In practice, decisions about allocation are made…
Cox-nnet is a neural-network based prognosis prediction method, originally applied to genomics data. Here we propose the version 2 of Cox-nnet, with significant improvement on efficiency and interpretability, making it suitable to predict…
Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…
A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE…
Kidney stones are a common and debilitating health issue, and genetic factors play a crucial role in determining susceptibility. While Genome-Wide Association Studies (GWAS) have identified numerous single nucleotide polymorphisms (SNPs)…
This study presents a machine learning-based framework for heart disease prediction using the heart-disease dataset, comprising 303 samples with 14 features. The methodology involves data preprocessing, model training, and evaluation using…
Acute kidney injury (AKI) is a serious clinical condition that affects up to 20% of hospitalised patients. AKI is associated with short term unplanned hospital readmission and post-discharge mortality risk. Patient risk and healthcare…
The COVID-19 pandemic has created an urgent need for robust, scalable monitoring tools supporting stratification of high-risk patients. This research aims to develop and validate prediction models, using the UK Biobank, to estimate COVID-19…
The C-Index measures the discrimination performance of survival prediction models. C-Index scores are often well below the upperbound of 1 that represents perfect prediction and closer to 0.5 as achieved by random prediction. Our first…
Wide heterogeneity exists in cancer patients' survival, ranging from a few months to several decades. To accurately predict clinical outcomes, it is vital to build an accurate predictive model that relates patients' molecular profiles with…
In this paper we utilize a survival analysis methodology incorporating Bayesian additive regression trees to account for nonlinear and additive covariate effects. We compare the performance of Bayesian additive regression trees, Cox…
Survival random forest is a popular machine learning tool for modeling censored survival data. However, there is currently no statistically valid and computationally feasible approach for estimating its confidence band. This paper proposes…
Heart disease is one of the most common diseases in middle-aged citizens. Among the vast number of heart diseases, the coronary artery disease (CAD) is considered as a common cardiovascular disease with a high death rate. The most popular…
Coronary Heart Disease affects millions of people worldwide and is a well-studied area of healthcare. There are many viable and accurate methods for the diagnosis and prediction of heart disease, but they have limiting points such as…
Accurate patient mortality prediction enables effective risk stratification, leading to personalized treatment plans and improved patient outcomes. However, predicting mortality in healthcare remains a significant challenge, with existing…
Stroke is the second leading cause of death worldwide. Machine learning classification algorithms have been widely adopted for stroke prediction. However, these algorithms were evaluated using different datasets and evaluation metrics.…
In this modern era of overpopulation disease prediction is a crucial step in diagnosing various diseases at an early stage. With the advancement of various machine learning algorithms, the prediction has become quite easy. However, the…