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The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

Multi-human parsing is the task of segmenting human body parts while associating each part to the person it belongs to, combining instance-level and part-level information for fine-grained human understanding. In this work, we demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Laura Bragagnolo , Matteo Terreran , Leonardo Barcellona , Stefano Ghidoni

Recently, deep learning has started to play an essential role in healthcare applications, including image search in digital pathology. Despite the recent progress in computer vision, significant issues remain for image searching in…

Image and Video Processing · Electrical Eng. & Systems 2023-04-19 Pooria Mazaheri , Azam Asilian Bidgoli , Shahryar Rahnamayan , H. R. Tizhoosh

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu

Recently, self-supervised Masked Autoencoders (MAE) have attracted unprecedented attention for their impressive representation learning ability. However, the pretext task, Masked Image Modeling (MIM), reconstructs the missing local patches,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Feng Liang , Yangguang Li , Diana Marculescu

Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Piumi Sandarenu , Julia Chen , Iveta Slapetova , Lois Browne , Peter H. Graham , Alexander Swarbrick , Ewan K. A. Millar , Yang Song , Erik Meijering

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Richard J. Chen , Rahul G. Krishnan

Histopathology whole slide images (WSIs) are being widely used to develop deep learning-based diagnostic solutions, especially for precision oncology. Most of these diagnostic softwares are vulnerable to biases and impurities in the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Abhijeet Patil , Harsh Diwakar , Jay Sawant , Nikhil Cherian Kurian , Subhash Yadav , Swapnil Rane , Tripti Bameta , Amit Sethi

Self-supervised representation learning methods often fail to learn subtle or complex features, which can be dominated by simpler patterns which are much easier to learn. This limitation is particularly problematic in applications to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Lucas Farndale , Paul Henderson , Edward W Roberts , Ke Yuan

Learning discriminative representations of unlabelled data is a challenging task. Contrastive self-supervised learning provides a framework to learn meaningful representations using learned notions of similarity measures from simple pretext…

Computer Vision and Pattern Recognition · Computer Science 2023-01-04 Nicklas Boserup , Raghavendra Selvan

Self-supervised pretraining followed by supervised fine-tuning has seen success in image recognition, especially when labeled examples are scarce, but has received limited attention in medical image analysis. This paper studies the…

This paper presents an autoencoder-based neural network architecture to compress histopathological images while retaining the denser and more meaningful representation of the original images. Current research into improving compression…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Agnes Barsi , Suvendu Chandan Nayak , Sasmita Parida , Raj Mani Shukla

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Medical experts often manually segment images to obtain diagnostic statistics and discard the resulting annotations. We aim to train segmentation models to alleviate this burden, but constrained to the retained summary statistics (e.g., the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Omkar Kulkarni , Edward Raff , Tim Oates

Is self-supervised deep learning (DL) for medical image analysis already a serious alternative to the de facto standard of end-to-end trained supervised DL? We tackle this question for medical image classification, with a particular focus…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Maximilian Nielsen , Laura Wenderoth , Thilo Sentker , René Werner

At the most basic level, pixels are the source of the visual information through which we perceive the world. Pixels contain information at all levels, ranging from low-level attributes to high-level concepts. Autoencoders represent a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Lihe Yang , Shang-Wen Li , Yang Li , Xinjie Lei , Dong Wang , Abdelrahman Mohamed , Hengshuang Zhao , Hu Xu

Interpretation of medical images for diagnosis and treatment of complex disease from high-dimensional and heterogeneous data remains a key challenge in transforming healthcare. In the last few years, both supervised and unsupervised deep…

Image and Video Processing · Electrical Eng. & Systems 2018-12-20 Khalid Raza , Nripendra Kumar Singh

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Deep-learning methods have recently started being employed for addressing surface-defect detection problems in industrial quality control. However, with a large amount of data needed for learning, often requiring high-precision labels, many…

Computer Vision and Pattern Recognition · Computer Science 2021-04-21 Jakob Božič , Domen Tabernik , Danijel Skočaj

In the recent years, convolutional neural networks have transformed the field of medical image analysis due to their capacity to learn discriminative image features for a variety of classification and regression tasks. However, successfully…

Computer Vision and Pattern Recognition · Computer Science 2019-07-08 Wenjia Bai , Chen Chen , Giacomo Tarroni , Jinming Duan , Florian Guitton , Steffen E. Petersen , Yike Guo , Paul M. Matthews , Daniel Rueckert