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Pooling specimens, a well-accepted sampling strategy in biomedical research, can be applied to reduce the cost of studying biomarkers. Even if the cost of a single assay is not a major restriction in evaluating biomarkers, pooling can be a…

Applications · Statistics 2012-03-01 Enrique F. Schisterman , Albert Vexler , Aijun Ye , Neil J. Perkins

Two distinct effects that polymers exhibit are shear thinning and viscoelasticity. The shear thinning effect is important as the polymers used in chemical enhanced oil recovery usually have this property. We propose a novel approach to…

Fluid Dynamics · Physics 2023-05-10 Prabir Daripa , Rohit Mishra

When injected through a contraction, high molecular weight polymer solutions exhibit a sharp increase of apparent viscosity which originates from stretching polymer chains above a critical extension rate. This chain stretching can also…

Fluid Dynamics · Physics 2020-04-22 Sandeep Garrepally , Stephane Jouenne , Peter D. Olmsted , Francois Lequeux

Flow-based generative models parameterize probability distributions through an invertible transformation and can be trained by maximum likelihood. Invertible residual networks provide a flexible family of transformations where only…

Machine Learning · Statistics 2020-07-27 Ricky T. Q. Chen , Jens Behrmann , David Duvenaud , Jörn-Henrik Jacobsen

We review some recent coarse-graining and multi-scale methods, but also put forward some new ideas for addressing such issues. We find that, if one is guided by nonequilibrium statistical mechanics and thermodynamics, it is possible to…

Soft Condensed Matter · Physics 2009-11-06 Patrick Ilg , Vlasis Mavrantzas , Hans Christian Öttinger

Density level sets can be estimated using plug-in methods, excess mass algorithms or a hybrid of the two previous methodologies. The plug-in algorithms are based on replacing the unknown density by some nonparametric estimator, usually the…

Statistics Theory · Mathematics 2016-11-26 A. Rodríguez-Casal , P. Saavedra-Nieves

We present a mathematical approach to optimize the material distribution for fluid transport in unsaturated porous media. Our benchmark problem is a simplified diaper model as an exemplary liquid absorber. Our model has up to three…

Computational Physics · Physics 2019-10-02 Fabian Wein , Nan Chen , Naveed Iqbal , Michael Stingl , Marc Avila

We propose an improved viscosity model accounting for experiments of emulsions of two immiscible liquids at arbitrary volume fractions and low shear rates. The model is based on a recursive-differential method formulated in terms of the…

Soft Condensed Matter · Physics 2009-04-01 Carlos I. Mendoza , I. Santamaria-Holek

Machine learning (ML) models for predicting gas permeability through polymers have traditionally relied on experimental data. While these models exhibit robustness within familiar chemical domains, reliability wanes when applied to new…

Materials Science · Physics 2024-06-24 Brandon K. Phan , Kuan-Hsuan Shen , Rishi Gurnani , Huan Tran , Ryan Lively , Rampi Ramprasad

The translocation of a polymer through a pore in a membrane separating fluids of different viscosities is studied via several computational approaches. Starting with the polymer halfway, we find that as a viscosity difference across the…

Soft Condensed Matter · Physics 2013-04-17 Hendrick W. de Haan , Gary W. Slater

This paper is concerned with singular shocks for a system of conservation laws modeling incompressible two-phase fluid flow. We prove the existence of viscous profiles using the Geometric Singular Perturbation Theory. Weak convergence and…

Analysis of PDEs · Mathematics 2016-11-09 Ting-Hao Hsu

Drag reduction by polymers in turbulent wall-bounded flows exhibits universal and non-universal aspects. The universal maximal mean velocity profile was explained in a recent theory. The saturation of this profile and the crossover back to…

Chaotic Dynamics · Physics 2016-09-08 Roberto Benzi , Victor S. L'vov , Itamar Procaccia , Vasil Tiberkevich

The estimation problem in a high regression model with structured sparsity is investigated. An algorithm using a two steps block thresholding procedure called GR-LOL is provided. Convergence rates are produced: they depend on simple…

Statistics Theory · Mathematics 2012-07-10 Mathilde Mougeot , Dominique Picard , Karine Tribouley

The structure and function of polymers in confined environments, e.g., biopolymers in the cytoplasm of a cell, are strongly affected by macromolecular crowding. To explore the influence of solvent quality on conformations of crowded…

Soft Condensed Matter · Physics 2018-09-27 Wyatt J. Davis , Alan R. Denton

Drag reduction by polymers in turbulent flows raises an apparent contradiction: the stretching of the polymers must increase the viscosity, so why is the drag reduced? A recent theory proposed that drag reduction in agreement with…

The performance of flow matching and diffusion models can be greatly improved at inference time using reward alignment algorithms, yet efficiency remains a major limitation. While several algorithms were proposed, we demonstrate that a…

Machine Learning · Computer Science 2026-02-12 Peter Holderrieth , Uriel Singer , Tommi Jaakkola , Ricky T. Q. Chen , Yaron Lipman , Brian Karrer

We present a phenomenological model for the mixing length used in turbulence models. It has the advantage of naturally accounting for the object's geometry while satisfying the standard symmetries of the Navier-Stokes equations. We employ…

Selective targeting of membranes with a specific receptor profile is an ongoing challenge in targeted drug delivery. We investigate the adsorption of copolymers on a multicomponent receptor-covered surface using grand-canonical Monte Carlo…

Soft Condensed Matter · Physics 2026-05-27 Vid Ravnik , Urban Bren , Tine Curk

Multi-component polymer systems are of interest in organic photovoltaic and drug delivery applications, among others where diverse morphologies influence performance. An improved understanding of morphology classification, driven by…

Computational Engineering, Finance, and Science · Computer Science 2020-08-27 Pavan Inguva , Lachlan Mason , Indranil Pan , Miselle Hengardi , Omar K. Matar

Probabilistic graphical models (PGMs) are tools for solving complex probabilistic relationships. However, suboptimal PGM structures are primarily used in practice. This dissertation presents three contributions to the PGM literature. The…

Machine Learning · Computer Science 2022-05-27 Simon Streicher