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Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

Finding meaningful clusters in drive-by-download malware data is a particularly difficult task. Malware data tends to contain overlapping clusters with wide variations of cardinality. This happens because there can be considerable…

Cryptography and Security · Computer Science 2021-04-26 Renato Cordeiro de Amorim , Carlos David Lopez Ruiz

The explosion in the amount of data available for analysis often necessitates a transition from batch to incremental clustering methods, which process one element at a time and typically store only a small subset of the data. In this paper,…

Machine Learning · Computer Science 2014-06-26 Margareta Ackerman , Sanjoy Dasgupta

The objective of clusterability evaluation is to check whether a clustering structure exists within the data set. As a crucial yet often-overlooked issue in cluster analysis, it is essential to conduct such a test before applying any…

Machine Learning · Computer Science 2025-01-07 Lianyu Hu , Junjie Dong , Mudi Jiang , Yan Liu , Zengyou He

Variational inference has been widely used in machine learning literature to fit various Bayesian models. In network analysis, this method has been successfully applied to solve the community detection problems. Although these results are…

Machine Learning · Statistics 2024-05-22 Xuezhen Li , Can M. Le

Similarity-based clustering methods separate data into clusters according to the pairwise similarity between the data, and the pairwise similarity is crucial for their performance. In this paper, we propose {\em Clustering by Discriminative…

Machine Learning · Computer Science 2022-06-24 Yingzhen Yang , Ping Li

Subset selection is an important component in evolutionary multiobjective optimization (EMO) algorithms. Clustering, as a classic method to group similar data points together, has been used for subset selection in some fields. However,…

Neural and Evolutionary Computing · Computer Science 2021-08-31 Weiyu Chen , Hisao Ishibuchi , Ke Shang

We introduce a new clustering method for the classification of functional data sets by their probabilistic law, that is, a procedure that aims to assign data sets to the same cluster if and only if the data were generated with the same…

Methodology · Statistics 2023-12-29 Antonio Galves , Fernando Najman , Marcela Svarc , Claudia D. Vargas

In regression and causal inference, controlled subgroup selection aims to identify, with inferential guarantees, a subgroup (defined as a subset of the covariate space) on which the average response or treatment effect is above a given…

Methodology · Statistics 2025-10-31 Nathan Cheng , Asher Spector , Lucas Janson

Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni…

Econometrics · Economics 2025-07-29 Sebastian Calonico , Sebastian Galiani

We study a statistical framework for replicability based on a recently proposed quantitative measure of replication success, the sceptical $p$-value. A recalibration is proposed to obtain exact overall Type-I error control if the effect is…

Methodology · Statistics 2023-11-10 Charlotte Micheloud , Fadoua Balabdaoui , Leonhard Held

Classification and clustering are both important topics in statistical learning. A natural question herein is whether predefined classes are really different from one another, or whether clusters are really there. Specifically, we may be…

Machine Learning · Statistics 2015-09-22 Qiyi Lu , Xingye Qiao

Variable selection in cluster analysis is important yet challenging. It can be achieved by regularization methods, which realize a trade-off between the clustering accuracy and the number of selected variables by using a lasso-type penalty.…

Methodology · Statistics 2016-12-23 Marbac Matthieu , Sedki Mohammed

The applicability of agglomerative clustering, for inferring both hierarchical and flat clustering, is limited by its scalability. Existing scalable hierarchical clustering methods sacrifice quality for speed and often lead to over-merging…

In the analysis of single-cell RNA sequencing data, researchers often characterize the variation between cells by estimating a latent variable, such as cell type or pseudotime, representing some aspect of the individual cell's state. They…

Methodology · Statistics 2022-10-19 Anna Neufeld , Lucy L. Gao , Joshua Popp , Alexis Battle , Daniela Witten

The problem of hierarchical clustering items from pairwise similarities is found across various scientific disciplines, from biology to networking. Often, applications of clustering techniques are limited by the cost of obtaining…

Machine Learning · Statistics 2012-07-20 Brian Eriksson

Clustering is a core task in machine learning with wide-ranging applications in data mining and pattern recognition. However, its unsupervised nature makes it inherently challenging. Many existing clustering algorithms suffer from critical…

Machine Learning · Computer Science 2025-07-29 Ahmed Shokry , Ayman Khalafallah

Generalized linear mixed models (GLMM) are commonly used to analyze clustered data, but when the number of clusters is small to moderate, standard statistical tests may produce elevated type I error rates. Small-sample corrections have been…

Methodology · Statistics 2023-11-07 Hongxiang Qiu , Andrea J. Cook , Jennifer F. Bobb

Discovering statistically significant patterns from databases is an important challenging problem. The main obstacle of this problem is in the difficulty of taking into account the selection bias, i.e., the bias arising from the fact that…

Machine Learning · Statistics 2016-03-10 Shinya Suzumura , Kazuya Nakagawa , Mahito Sugiyama , Koji Tsuda , Ichiro Takeuchi

We define the notion of a well-clusterable data set combining the point of view of the objective of $k$-means clustering algorithm (minimising the centric spread of data elements) and common sense (clusters shall be separated by gaps). We…

Machine Learning · Computer Science 2020-04-07 Mieczysław A. Kłopotek
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