Related papers: A Hele-Shaw limit without monotonicity
We study the dynamics of the interface between two incompressible 2-D flows where the evolution equation is obtained from Darcy's law. The free boundary is given by the discontinuity among the densities and viscosities of the fluids. This…
We analyze the contact Hele-Shaw problem with zero surface tension of a free boundary in a thin domain $\Omega^{\varepsilon}(t).$ Under suitable conditions on the given data, the one-valued local classical solvability of the problem for…
We consider a class of tumor growth models under the combined effects of density-dependent pressure and cell multiplication, with a free boundary model as its singular limit when the pressure-density relationship becomes highly nonlinear.…
Using formal asymptotic methods we derive a free boundary problem representing one of the simplest mathematical descriptions of the growth and death of a tumour or other biological tissue. The mathematical model takes the form of a closed…
This paper is devoted to the analysis of a singular perturbation problem for a $2$-D incompressible MHD system with density variations and Coriolis force, in the limit of small Rossby numbers. Two regimes are considered. The first one is…
We consider a macroscopic model for the growth of living tissues incorporating pressure-driven dispersal and pressure-modulated proliferation. Assuming a power-law relation between the mechanical pressure and the cell density, the model can…
We develop a numerical method for solving a free boundary problem which describes shape relaxation, by surface tension, of a long and thin bubble of an inviscid fluid trapped inside a viscous fluid in a Hele-Shaw cell. The method of…
A pair of concentric spheres separated by a small gap form a spherical Hele-Shaw cell. In this cell an interfacial instability arises when two immiscible fluids flow. We derive the equation of motion for the interface perturbation…
We present a two-species model with applications in tumour modelling. The main novelty is the coupling of both species through the so-called Brinkman law which is typically used in the context of visco-elastic media, where the velocity…
We develop a systematic method to derive all orders of mode couplings in a weakly nonlinear approach to the dynamics of the interface between two immiscible viscous fluids in a Hele-Shaw cell. The method is completely general. It includes…
We study a quite general family of nonlinear evolution equations of diffusive type with nonlocal effects. More precisely, we study porous medium equations with a fractional Laplacian pressure, and the problem is posed on a bounded space…
In this paper we make rigorous mathematical analysis to a free boundary problem modeling the growth of necrotic tumors. A remarkable feature of this free boundary problem is that it contains two different-type free surfaces: One is the…
The paper deals with homogenization of a model problem describing an immiscible compressible two-phase flow in random statistically homogeneous porous media. We derive the effective (macroscopic) problem and prove the convergence of…
We describe the competitive motion of (N + 1) incompressible immiscible phases within a porous medium as the gradient flow of a singular energy in the space of non-negative measures with prescribed mass endowed with some tensorial…
We address numerical challenges in solving hyperbolic free boundary problems described by spherically symmetric conservation laws that arise in the modeling of tumor growth due to immune cell infiltrations. In this work, we normalize the…
We develop an existence and regularity theory for solutions to a geometric free boundary problem motivated by models of tumor growth. In this setting, the tumor invades an accessible region $D$, its motion is directed along a constant…
We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…
We consider the propagation of nonlinear plane waves in porous media within the framework of the Biot-Coussy biphasic mixture theory. The tortuosity effect is included in the model, and both constituents are assumed incompressible…
We consider a nonlocal approximation of the quadratic porous medium equation where the pressure is given by a convolution with a mollification kernel. It is known that when the kernel concentrates around the origin, the nonlocal equation…
In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…